Cardiac malformations

Left-sided lesions (LSLs) account for an important fraction of severe congenital cardiovascular malformations (CVMs). The genetic contributions to LSLs are complex, and the mutations that cause these malformations span several diverse biological signaling pathways: TGFB, NOTCH, SHH, and more.

10p vioraclene 31-03-2024 8 2   Download

Part 1 book "Feline cardiology" includes content: Heart murmurs and gallop heart sounds, exercise intolerance and syncope; pleural effusion; dyspnea and cough; cardiopulmonary arrest and cardiopulmonary cerebral resuscitation, radiography; echocardiography; cardiac biomarkers; electrocardiography; congenital heart malformations; hypertrophic cardiomyopathy; restrictive unclassified cardiomyopathy; dilated cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; cardiac neoplasia; miscellaneous myocardial disease.

205p oursky10 04-12-2023 5 3   Download

Intracranial hemorrhage, including subarachnoid hemorrhage (SAH), is associated with many cardiac effects, including cardiac rhythm abnormalities, ischemic electrocardiographic (ECG) changes, elevated cardiac troponin levels, and regional wall motion abnormalities on echocardiogram.

6p viwhitewolf 03-07-2023 4 2   Download

Loss of proprotein convertase subtilisin/kexin type 5 (Pcsk5) results in multiple developmental anomalies including cardiac malformations, caudal regression, pre-sacral mass, renal agenesis, anteroposterior patterning defects, and tracheo-oesophageal and anorectal malformations, and is a model for VACTERL/caudal regression/Currarino syndromes (VACTERL association - Vertebral anomalies, Anal atresia, Cardiac defects, Tracheoesophageal fistula and/or Esophageal atresia, Renal & Radial anomalies and Limb defects).

10p viwyoming2711 16-12-2020 11 1   Download

13q33–q34 microdeletions are rare chromosomal aberrations associated with a high risk of developmental disability, facial dysmorphism, cardiac defects and other malformation of organs. It is necessary to collect and report evidence of this rare chromosome mutation to improve the prognosis of this rare disease.

6p vimanama2711 28-07-2020 13 2   Download

Tuberous sclerosis complex (TSC) is an autosomal-dominant tumor suppressor gene syndrome that is characterized by the development of distinctive benign tumors and malformations in multiple organ systems (N Eng J Med 355:1345-1356, 2006).

5p vichengna2711 25-02-2020 15 1   Download

Congenital heart disease (CHD) is the most prevalent congenital malformation affecting 1 in 100 newborns. While advances in early diagnosis and postnatal management have increased survival in CHD children, worrying long-term outcomes, particularly neurodevelopmental disability, have emerged as a key prognostic factor in the counseling of these pregnancies.

10p vidublin2711 13-01-2020 28 1   Download

(BQ) Part 2 of the document Cerebral angiography normal anatomy and vascular pathology presents the following contents: Vascular malformations of the central nervous system, dural arteriovenous fistulas, arteriovenous fistulas, ischemic stroke, spontaneous dissection of carotid and vertebral arteries,...

205p thangnamvoiva4 01-07-2016 51 3   Download

Congenital heart defects occur in approximately 1% of newborns and are a major cause of morbidity and mortality in infants and children. Many adult cardiac diseases also have developmental basis, such as heart valve malformations, among others. Therefore, dissecting the developmental and molecular mechanisms underlying such defects in embryos is of great importance in prevention and developing therapeutics for heart diseases that manifest in infants or later in adults.

356p thienbinh1311 13-12-2012 51 4   Download

For much of the early history of medicine, the heart was considered to be the most sacred and mystical of all human organs. As a General Pediatrician, I tend to expect that the children I care for will have strong, properly functioning hearts. However, in situations where the heart is congenitally malformed or affected by inflammation or myopathy, it is reassuring and important to have a pediatric cardiologist and cardiac surgeon at my side to help me with decisions about further diagnostic testing and imaging, instituting medical therapy, and assessing the need for surgical intervention....

382p bachduong1311 10-12-2012 65 6   Download

As one ascends rapidly to 3000 m (~10,000 ft), the reduction of the O 2 content of inspired air (FIO2) leads to a decrease in alveolar PO2 to about 60 mmHg, and a condition termed high-altitude illness develops (see above). At higher altitudes, arterial saturation declines rapidly and symptoms become more serious; and at 5000 m, unacclimatized individuals usually cease to be able to function normally.

5p ongxaemnumber1 29-11-2010 82 3   Download