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Care chemotherapy
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The current standard of care in the neoadjuvant setting for high-risk HER2-positive (HER2+) breast cancer is to combine systemic chemotherapy with dual HER2 blockade, trastuzumab and pertuzumab. Targeted therapies have significantly improved outcomes for patients with HER2-positive breast cancer.
8p
vikoch
27-06-2024
1
1
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Oxaliplatin-based chemotherapy represents a standard of care in the treatment of metastatic colorectal cancer. We report a rare case of fulminant oxaliplatin-induced thrombotic microangiopathy, clinically suggestive of hemolytic–uremic syndrome, occurring in a female patient with a prolonged history of exposure to oxaliplatin for the treatment of metastatic colon cancer.
6p
vitiki
30-01-2024
6
2
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We describe the association between initial treatment and end-of-life (EOL) outcomes among patients with pancreatic ductal adenocarcinoma (PDAC). Receiving cancer-directed therapies was associated with higher survival, fewer healthcare visits, lower odds of dying in an institution and hospitalization at EOL, fewer palliative care visits, and higher odds of receiving chemotherapy at EOL.
9p
vileonardodavinci
23-12-2023
7
3
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Urothelial carcinoma (UC) is the ninth most commonly diagnosed cancer worldwide, with a 3.8/1 male to female ratio. Platinum-based chemotherapy is the first line standard of care for ft patients with advanced UC.
11p
vileonardodavinci
23-12-2023
4
3
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For patients with acute myeloid leukaemia (AML), the only potentially curative treatment is intensive chemotherapy (IC). This is highly toxic, particularly for patients>60 years, potentially leading to prolonged hospitalisations requiring intensive supportive care, and sometimes treatment-related death. This also results in extensive healthcare costs and negatively impacts quality of life (QoL).
13p
vileonardodavinci
23-12-2023
3
3
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The objective of this study was to investigate the tolerance of capecitabine, an example of oral chemotherapy, among older adults with cancer and explore factors associated with capecitabine-related side effects and treatment changes, to enhance supportive care.
14p
vialfrednobel
23-12-2023
5
4
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Radiotherapy of head-and-neck cancer (SCCHN) is often associated with acute toxicity. In a previous trial, daily reminders by staff members to perform skin care resulted in less dermatitis. This randomized trial investigated whether a mobile application can replace these reminders.
9p
vialfrednobel
23-12-2023
4
3
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Part 1 book "Oncology for veterinary technicians and nurses" includes content: Introduction to clinical veterinary oncology, causes of cancer in pets, diagnosis of cancer; staging of cancer; general principles of veterinary cancer treatment; surgery in veterinary oncology; radiation therapy; chemotherapy; biotherapy and photodynamic therapy; complementary and alternative medical (CAM) therapies; comfort, pain management, and physical rehabilitation; gastrointestinal and nutritional support; hematologic support; euthanasia and end of life patient care.
146p
oursky09
12-11-2023
10
5
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Up to 70% of breast cancer patients report symptoms of insomnia during and after treatment. Despite the ubiquity of insomnia symptoms, they are under-screened, under-diagnosed and poorly managed in breast cancer patients. Sleep medications treat symptoms but are ineffective to cure insomnia.
12p
visharma
20-10-2023
5
2
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Surgical resection followed by adjuvant mFOLFIRINOX (5-fluorouracil with leucovorin, irinotecan, and oxaliplatin) is currently the standard of care for patients with resectable pancreatic cancer. The main concern regarding adjuvant chemotherapy is that only half of patients actually receive adjuvant treatment.
8p
vioracle
29-09-2023
4
2
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Small-cell lung cancer (SCLC) is a highly aggressive and lethal malignancy that accounts for 10–15% of lung cancers, and it is generally divided into limited and extensive stage. The standard of care for patients with newly diagnosed extensive-stage SCLC (ES-SCLC) is still platinum-based chemotherapy and as maintenance therapy scheme.
11p
vioracle
29-09-2023
5
3
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Non-metastatic breast cancer treatment is mainly based on surgery, with or without chemotherapy, radiotherapy and/or hormone therapy. To reduce the risk of hormone receptor positive (HR+) disease recurrence, hormone therapy is prescribed for at least 5 years.
10p
vioracle
29-09-2023
7
3
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The incidence of peripherally inserted central catheter (PICC)-related complications is higher in cancer patients than in noncancer patients. However, the pattern of specific complication occurrence over time remains unclear.
11p
vioracle
29-09-2023
3
2
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Heart rate variability (HRV) is widely used to demonstrate the vagal function and sympathetic function of the autonomic nervous system and evaluate autonomic dysregulation. Current literature demonstrated that the HRV of women who have gone through breast cancer, surgery and chemotherapy stays low for possibly up to a year or more.
8p
viintuit
26-09-2023
4
0
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Unique features and treatment effects of trabectedin are presented in consideration of soft tissue sarcoma management. A prolonged time on trabectedin through 59 cycles is shown. This is one of the longer reported uses of trabectedin successfully to control disease.
4p
viintuit
26-09-2023
2
0
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Ebook Otorhinolaryngology head and neck surgery (Vol 3, 8th edition): Part 1 includes content: Aetiology of head and neck cancer, epidemiology of head and neck carcinoma, staging of head and neck cancer, rehabilitation after total laryngectomy, metastatic neck disease, palliative care for head and neck cancer, transoral laser microsurgery, principles of chemotherapy.
665p
oursky02
06-08-2023
6
2
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Concurrent chemoradiotherapy is currently the standard of care for patients with locally advanced cervical cancer. However, even with the application of modern radiotherapy techniques, a considerable number of patients still develop distant metastases. PD-L1 inhibitors show good efficacy in cervical cancer.
9p
vikolindagrabar
27-07-2022
8
1
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Radio-chemotherapy with 5-fluorouracil (5-FU) is the standard of care treatment for patients with colorectal can‑ cer, but it is only effective for a third of them. Despite our understanding of the mechanism of action of 5-FU, drug resistance remains a significant limitation to the clinical use of 5-FU, as both intrinsic and acquired chemoresistance represents the major obstacles for the success of 5-FU-based chemotherapy.
19p
vikolindagrabar
27-07-2022
5
1
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Postoperative adjuvant cisplatin-based chemotherapy had been the standard care in patients with completely resected high-risk stage IB to IIIA non-small cell lung cancer (NSCLC) for decades. However, the survival benefits were far from satisfactory in clinical practice.
15p
vikolindagrabar
27-07-2022
6
4
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Both modified FOLFIRINOX (mFFX) and gemcitabine/nab-paclitaxel chemotherapy regimens have been shown to improve clinical outcomes in patients with pancreatic cancer, and are often used interchangeably as the standard of care.
11p
viangelamerkel
27-07-2022
8
2
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