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CAS assay
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We evaluated the performance of single-nucleotide polymorphism (SNP) genotyping arrays OncoScan (Thermo Fisher Scientific, San Diego, CA) and Infinium CytoSNP-850K (CytoSNP; Illumina, Waltham, MA) for assessing homologous recombination deficiency (HRD) genomic instability.
9p
vileonardodavinci
23-12-2023
4
3
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Với mục tiêu phân lập, tuyển chọn và khảo sát đặc điểm sinh học của các dòng thực khuẩn thể làm tiền đề cho những nghiên cứu ứng dụng để kiểm soát bệnh xuất huyết trên cá tra gây ra do A. hyrophila, 26 dòng thực khuẩn thể đã được phân lập bằng phương pháp Plaque Assay từ 100 mẫu nước ao nuôi cá ở tỉnh Tiền Giang.
5p
viclerkmaxwel
16-02-2022
18
3
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Cancer is a disease characterized by the continuous growth of cells without adherence to the rules that healthy normal cells obey. Carbonic anhydrase I and II (CA I and CA II) inhibitors are used for the treatment of some diseases. The available drugs in the market have limitations or side effects, which bring about the need to develop new drug candidate compound(s) to overcome the problems at issue.
35p
tudichquannguyet
29-11-2021
5
1
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Mucin-1 is known to be over-expressed by various human carcinomas and is shed into the circulation where it can be detected in patient’s serum by specific anti-Mucin-1 antibodies, such as the tumour marker assays CA 15–3 and CA 27.29. The prognostic value of Mucin-1 expression in ovarian carcinoma remains uncertain.
9p
vijisoo2711
30-09-2020
4
0
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African American (AA) colon cancer patients have a worse prognosis than Caucasian (CA) colon cancer patients, however, reasons for this disparity are not well understood. To determine if tumor biology might contribute to differential prognosis, we measured recurrence risk and gene expression using the Oncotype DX® Colon Cancer Assay (12-gene assay) and compared the Recurrence Score results and gene expression profiles between AA patients and CA patients with stage II colon cancer.
7p
vinaypyidaw2711
26-08-2020
11
1
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In the presence of sufficient iron, the Escherichia coli protein Fur (Ferric Uptake Regulator) represses genes controlled by the Fur box, a consensus sequence near or within promoters of target genes. De-repression of Fur-controlled genes occurs upon iron deprivation.
11p
vihamax2711
21-04-2020
12
1
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Cơ sở dữ liệu về trình tự promoter đã chứng minh trình tự ADN đích CCTCCTCC có mặt phổ biến trong các promoter cảm ứng với điều kiện stress của các gen chức năng liên quan đến stress như hạn, mặn và lạnh. Ngoài ra, các nghiên cứu phân tích chức năng của hai promoter cảm ứng với stress cho thấy promoter JRC0332 biểu hiện đặc trưng trong điều kiện lạnh và promoter JRC0528 biểu hiện trong điều kiện mặn, hạn, lạnh và có mặt ABA. Cả hai promoter này đều có chứa trình tự đích.
9p
trinhthamhodang
24-10-2019
29
1
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Preparation and characterisation of attenuated cold-adapted influenza A reassortants derived from the A/Leningrad/134/17/57 donor strain presents the assay was capable of detecting interference where the infectivity ratio for A/Len/17 and A/Beij/32 was 1:7. Progeny viruses were characterised genetically by amplification of defined regions within each of the six internal genes by PCR and identification of the products by restriction enzyme analysis.
9p
thuyancn
01-06-2015
39
4
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As recently demonstrated by overlay assays using calseque-strin-peroxidase conjugates, the major 63 kDa Ca 2+ -bind-ing protein of the sarcoplasmic reticulum forms complexes with itself, and with junctin (26 kDa), triadin (94 kDa) and the ryanodine receptor (560 kDa) [Glover, L., Culligan, K., Cala, S., Mulvey, C. & Ohlendieck, K. (2001)Biochim. Biophys. Acta1515, 120–132].
10p
research12
23-04-2013
29
1
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The effect of gadolinium ions on the sarcoplasmic reticulum (SR) calcium release channel⁄ryanodine receptor (RyR1) was studied using heavy SR (HSR) vesicles and RyR1 isolated from rabbit fast twitch muscle. In the [ 3 H]ryanodine binding assay, 5lmGd 3+ increased the Kd of the [ 3 H]ry-anodine binding of the vesicles from 33.8 nmto 45.6 nmwhileBmax, refer-ring to the binding capacity, was not affected significantly. In the presence of 18 nm[ 3 H]ryanodine and 100lmfree Ca 2+ ,Gd 3+ inhibited the binding of the radiolabeled ryanodine with an apparentKd value of 14.
0p
awards
05-04-2013
30
2
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In the search for a new framework, we have come to believe strongly in emerging management principles based on the “new science” of complexity that exploit an understanding of autonomous human behavior gained from the study of living systems in nature. Specifically, we have begun to build the notion of complex adaptive systems (CAS) into our management assumptions and practices. Complexity scientists have studied the collective behavior of living systems in nature such as the flocking of birds, schooling of fish, marching of ants and the swarming of bees.
8p
tay_thi_le
21-02-2013
54
3
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Small samples and study area covering only 2 DOTS centers are some of the study limitations. Other limitations include exclusion of testing for latent TB infection (LTBI). This was as a result of shortcomings associated with use of the only available diagnostic tool- Tuberculin (Mantoux) skin test (TST). These include invasive nature of the test, the need for the patient to come back for follow up TST reading, cross-reactivity with environmental mycobacteria and previous BCG vaccination.
5p
taisaocothedung
12-01-2013
44
1
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Chẩn đoán và phát hiện CMV (Cucumber Mosaic Virus), TMV (Tobacco Mosaic Virus) và TSWV (Tomato Spotted Wilt Virus) trong mẫu lá nghi ngờ bệnh virus bằng kỹ thuật DAS - ELISA (double antibody sanwich - enzyme linked immunosorbent assay). Từ đó, đánh giá tình hình bệnh ở khu vực nghiên cứu.
12p
zues02
18-06-2011
206
22
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Lung Cancer Chest x-ray and sputum cytology have been evaluated in randomized lung cancer screening trials. No reduction in lung cancer mortality has been seen, although all the controlled trials have had low statistical power. Even screening of high-risk subjects (smokers) has not proven beneficial. Spiral CT can diagnose lung cancers at early stages; however, false-positive rates are high. Spiral CT screening increases the number of lesions detected and increases the number of diagnostic and therapeutic procedures. However, its capacity to save lives is unproven.
8p
konheokonmummim
03-12-2010
123
2
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