Cases of pulmonary tuberculosis
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Several studies have compared the diagnostic value of sputum induction (SI) with flexible fiberoptic bronchoscopy (FOB) in diagnosing pulmonary tuberculosis; however, these investigations yield an inconsistent conclusion. This study aims to evaluate the role of acid-fast bacilli (AFB) testing of SI and bronchoalveolar lavage (BAL) samples in suspected pulmonary tuberculosis cases.
7p vikissinger 21-12-2023 3 2 Download
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Tuberculosis (TB) is caused by Mycobacterium tuberculosis and most commonly occurs in the lung. Only 10-15% of all cases of tuberculosis occur outside the respiratory system. Whereas secondary tuberculosis of the tonsil, where there is sputum-positive pulmonary TB, has been well documented, primary tuberculosis of the tonsil without pulmonary TB is rare, and only a few cases have been reported up to now.
3p viintuit 26-09-2023 1 0 Download
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Patients with drug resistant tuberculosis (DR-TB) with comorbidities and drug toxicities are difficult to treat. Guidelines recommend such patients to be managed in consultation with a multidisciplinary team of experts (the “TB consilium”) to optimise treatment regimens.
8p vimackenziebezos 29-11-2021 8 1 Download
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Despite incarcerated population being at an increased risk of tuberculosis (TB) and serving as a potential source of TB transmission for the general population, prison TB remains understudied. Given its adverse impact on progress towards TB elimination, World Health Organization (WHO) has identified prison TB research as a top priority to guide TB treatment/control interventions.
8p vimackenziebezos 29-11-2021 7 1 Download
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Tuberculosis, as a communicable disease, is an ongoing global epidemic that accounts for high burden of global mortality and morbidity. Globally, with an estimated 10 million new cases and around 1.4 million deaths, TB has emerged as one of the top 10 causes of morbidity and mortality in 2019.
14p vimackenziebezos 29-11-2021 5 1 Download
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Intravesical instillation of bacillus Calmette–Guérin (BCG) as a treatment for superfcial bladder cancer rarely causes pulmonary complications. While published cases have been pathologically characterized by multiple granulomatous lesions due to disseminated infection, no case presenting as a solitary pulmonary nodule has been reported.
5p vianthony2711 16-04-2021 19 2 Download
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Sputum smear conversion is a key indicator of treatment response and reduced infectivity among bacteriologically confrmed pulmonary tuberculosis (PTB) patients. This study aimed at estimating sputum smear conversion and identifying factors hindering sputum smear conversion among bacteriologically confrmed PTB cases in East Gojjam Zone, Northwest Ethiopia.
10p vianthony2711 16-04-2021 24 1 Download
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2′-5′-Oligoadenylate synthetase 1 (OAS1) plays an important role in inflammatory immune reactions. OAS1 polymorphisms have been associated with increased susceptibility to various diseases. We investigated the association of polymorphisms in OAS1 with tuberculosis (TB).
10p vimontana2711 05-04-2021 5 2 Download
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Extra-pulmonary tuberculosis (EPTB) is defined as any bacteriologically confirmed or clinically diagnosed case of TB involving organs other than the lungs. It is frequently a diagnostic and therapeutic challenge with paucity of data available.
7p vimontana2711 05-04-2021 8 1 Download
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F-fluorodeoxyglucose positron emission tomography (FDG-PET) is increasingly used to investigate for malignancy in the evaluation of pulmonary nodules, yet both active tuberculosis (TB) and malignancy have high uptake of FDG. Definitive diagnosis of TB can be further hindered in patients without growth of the organism from sputum.
5p vimontana2711 05-04-2021 17 2 Download
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Being a contact of a pulmonary tuberculosis (TB) case is a risk factor for active and latent TB. The objective of this study is to determine the contact tracing yield using two different programmatic definitions of close contact in the city of Rio de Janeiro, Brazil.
8p vimontana2711 05-04-2021 11 1 Download
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The management and control of pulmonary bacteriologically confirmed (PBC) tuberculosis (TB) also known as infectious TB is important not only to monitor for resistance but also to check for severity, treatment response and limit its spread.
8p vimaine2711 26-03-2021 8 2 Download
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Hepatitis in young children with tuberculosis (TB) outside miliary TB is not well described and represents a challenge because of the hepatotoxicity associated with first-line anti-TB treatment.
4p vimichigan2711 26-03-2021 10 2 Download
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Granulomatous polyangiitis (GPA) is a rare multisystem autoimmune disease of unknown aetiology that is pathologically characterised by necrotising vasculitis, tissue necrosis and granulomatous inflammation, typically in the presence of anti-neutrophil cytoplasmic antibodies (ANCA).
5p vimichigan2711 26-03-2021 17 2 Download
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Secondary organizing pneumonia (SOP) is difficult to distinguish from cryptogenic organizing pneumonia (COP) considering various clinical situations. SOP caused by Mycobacterium tuberculosis is rare; indeed, it has not been reported as a sequela of disseminated tuberculosis.
9p vimichigan2711 26-03-2021 13 2 Download
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The aim of the present study was to evaluate the association of NRAMP1 -3′UTR, 274-CT,VDR- Fok1 VDR-Taq1 Polymorphisms with the risk of pulmonary tuberculosis. 3′UTR-NRAMP1 gene and VDR-Taq1 gene Polymorphisms are statistically associated with the susceptibility of TB in Andhra Pradesh Population in India.
6p vimaine2711 26-03-2021 9 1 Download
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Tracheobronchial stenosis is a known complication of endobronchial tuberculosis. Despite antituberculous and steroid therapy, the development of bronchial stenosis is usually irreversible and requires airway patency to be restored by either bronchoscopic or surgical interventions.
6p vimaine2711 26-03-2021 4 1 Download
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Acute fibrinous and organizing pneumonia (AFOP) is a very rare form of acute or subacute lung injury, which is characterized by patches of “fibrin balls” distributed within the alveoli. Given the lack of typical clinical manifestations, AFOP is often misdiagnosed as pneumonia, tuberculosis, etc. Definitive diagnosis is obtained from a lung biopsy. Corticosteroids are usually effective.
6p vimaine2711 26-03-2021 12 2 Download
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Each year, more than 13.7 million people became an active case of tuberculosis and more than 1.5 million cases of TB patient will die. The association between TB and malnutrition is bi-directional, TB leads the patient to malnutrition, and malnutrition increases the risk of developing active TB by 6 to 10 times.
9p vimaine2711 26-03-2021 13 3 Download
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The failure of current Standard Short-Course Chemotherapy (SCC) in new and previously treated cases with tuberculosis (TB) was mainly due to drug resistance development. But little is known on the characteristics of acquired drug resistant TB during SCC and its correlation with SCC failure.
9p vimaine2711 26-03-2021 15 1 Download