Cell polarity

Recent studies have shown that blue light-emitting diode (LED) light has anti-tumor effects, suggesting the possibility of using visible light in cancer therapy. However, the effects of blue light irradiation on cells in the tumor microenvironment, including tumor-associated macrophages (TAMs), are unknown.

10p vikoch 27-06-2024 2 1   Download

Ebook "p53 Protocols (Second edition)" expert researchers in the field detail many of the methods that address the challenging questions of the p53 field. These methods include the identification of the target genes and binding partners of gain of function p53 mutants, methods to determine stress response, autophagy or senescence induced by p53, cell cycle analysis, analysis of different phases of DNA replication modified by p53, and generation of pluripotent stem cells.

251p dongmelo 27-05-2024 3 2   Download

Ebook "Biology of the fungal cell: Volume VIII (2nd edition)" provides readers with contents including: the endomembrane system of the fungal cell; motile tubular vacuole systems; the fungal woronin body; a molecular and genomic view of the fungal cell wall; the cytoskeleton and polarized growth of filamentous fungi; polarised growth in fungi; signal transduction and morphogenesis in candida albicans;...

353p ladongphongthanh1008 22-04-2024 5 1   Download

Ebook "Cell polarity 2: Role in development and disease" provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer).

228p ladongphongthanh1008 22-04-2024 2 1   Download

Ebook "Pluripotency in domestic animal cells" addresses why we need large animal models for regenerative medicine. It also describes early embryo development with a careful and specific analysis of the regulatory mechanisms driving cleavage, polarization and genome activation in domestic species. How pluripotency is compartmentalized in domestic species as well as the different aspects that make the derivation of stem cells in domestic species very difficult are also addressed.

52p manmanthanhla0201 26-02-2024 2 1   Download

Ebook "Cell polarity 1: Biological role and basic mechanisms" provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 1 addresses cell polarity and cell migration (front-rear polarity), cell polarity and barrier formation (apico-basal polarity) and neuronal polarity. It particularly focuses on cell polarity at the molecular level and the underlying molecular mechanisms. It also elaborates the common principles and mechanisms that regulate cellular polarization in different cell types and contexts.

396p manmanthanhla0201 26-02-2024 3 1   Download

Ebook "Fluorescence spectroscopy in biology: Advanced methods and their applications to membranes, proteins, dna, and cells" focuses on two new approaches in cell fluorescence microscopy. R. Brock shows how to characterize diffusion in cells by fluorescence correlation spectroscopy. The last two contributions by S. Rosenthal and O. Minet are devoted to photophysics and the use of quantum dots in cell imaging.

315p manmanthanhla0201 27-02-2024 3 2   Download

Ebook "Endocytosis in plants" presents an overview of our current knowledge of endocytosis in plants with a main focus on the key molecules undergoing and regulating endocytosis. It also provides up to date methodological approaches as well as principles of protein, structural lipid, sugar and microbe internalization in plant cells. The individual chapters describe clathrin-mediated and fluid-phase endocytosis, as well as flotillin-mediated endocytosis and internalization of microbes.

337p tachieuhoa 28-01-2024 7 2   Download

Exosomes are a new way of the communication between the tumor cell and macrophage in the micro-environment. The macrophage can be induced to different phenotypes according to the different tumors. In the present study, long-chain noncoding RNA HOTAIR (lncRNA HOTAIR) was highly expressed in LSCC and exosomes. The pathway of exosomal lncRNA HOTAIR inducing macrophage to M2 polarization in the LSCC was investigated.

13p vileonardodavinci 23-12-2023 4 3   Download

Recapitulating the tumor microenvironment (TME) in vitro remains a major hurdle in cancer research. In recent years, there have been significant strides in this area, particularly with the emergence of 3D spheroids as a model system for drug screening and therapeutics development for solid tumors. However, incorporating macrophages into these spheroid cultures poses specific challenges due to the intricate interactions between macrophages and cancer cells.

17p vileonardodavinci 23-12-2023 4 2   Download

Tumor-associated macrophages (TAMs) are the most abundant types of immune cells in the tumor microenvironment (TME) of breast cancer (BC). TAMs usually exhibit an M2 phenotype and promote tumor progression by facilitating immunosuppression. This study aimed to investigate the effect of CAA-derived IL-6 on macrophage polarization in promoting BC progression.

15p vischultz 20-10-2023 1 1   Download

Part 2 book "Encyclopedia of immunobiology (Vol 1 - Development and phylogeny of the immune system)" includes content: TCR affinity and signaling during thymocyte selection, control of migration during intrathymic T cell development, development of regulatory Y cells in the thymus, macrophage activation and polarization, kupffer cells in immunity, mast cells in allergy, host defense, and immune regulation,.... and other contents.

275p oursky06 17-10-2023 4 3   Download

Cathodic polarization is investigated as a technique for CRUD build-up mitigation in simulated primary pressurized water reactor conditions and accelerated flow. This investigation showed that the application of 3 V could induce a 67% reduction in surface deposition whilst 30 V cell voltage completely prevented the formation of surface deposits.

6p vironald 15-12-2022 8 3   Download

Using chemicals known as inhibitors of chromatin remodeling enzymes is a useful approach in understanding the regulation machinery that contributes to the maintenance of or conversion to a pluri- and totipotent states of the cells in multicellular organisms. They can serve as tools to reveal the molecular and cellular mechanisms required for reprogramming. A deeper understanding of reprogramming pathways that drive the cell into a dedifferentiated state might help us enhance plant micropropagation and green biotechnology applications.

9p tudichquannguyet 29-11-2021 12 1   Download

A low tissue oxygen level, < 1% O2, is a typical characteristic inside of solid tumors in head and neck cancer (HNSCC) affecting a wide array of cell populations, such as macrophages. However, the mechanisms of how hypoxia influences macrophages are not yet fully elucidated.

13p vimahuateng 26-11-2021 14 1   Download

Breast cancer is the leading cause of cancer-related deaths in females worldwide. Formin-like protein 2 (FMNL2) is a member of formin family that governs cytokinesis, cell polarity, morphogenesis and cell division. To our knowledge, the function of FMNL2 in breast cancer proliferation still remains uncovered.

13p vimahuateng 26-11-2021 12 1   Download

Consequently, a polarizationconversion mode is obtained with a high cross-polarization reflection in a broadband region (where the cross-polarization coefficient reaches up to 75 % in the frequency-range of 12.5 - 16.5 GHz). The polarization conversion was verified by experiment and the mechanism was clarified by the simulation of induced electric and magnetic fields. Our work could contribute to metamaterial-based multifunctional devices such as filter and polarization modulators.

9p spiritedaway36 25-11-2021 10 1   Download

Caenorhabditis elegans can endure long periods of environmental stress by altering their development to execute a quiescent state called “dauer”. Previous work has implicated LKB1 - the causative gene in the autosomal dominant, cancer pre-disposing disease called Peutz-Jeghers Syndrome (PJS), and its downstream target AMPK, in the establishment of germline stem cell (GSC) quiescence during the dauer stage.

19p vibeauty 23-10-2021 11 1   Download

The emergence of epithelia was the foundation of metazoan expansion. Epithelial tissues are a hallmark of metazoans deeply rooted in the evolution of their complex developmental morphogenesis processes. However, studies on the epithelial features of non-bilaterians are still sparse and it remains unclear whether the last common metazoan ancestor possessed a fully functional epithelial toolkit or if it was acquired later during metazoan evolution.

15p vibeauty 23-10-2021 8 1   Download

Root hair, a special type of tubular-shaped cell, outgrows from root epidermal cell and plays important roles in the acquisition of nutrients and water, as well as interactions with biotic and abiotic stress. Although many genes involved in root hair development have been identified, genetic basis of natural variation in root hair growth has never been explored.

11p vitzuyu2711 29-09-2021 5 1   Download