Central nervous system adverse effects

Gabapentin is commonly prescribed for the treatment of neuropathic pain, restless leg syndrome, and partial-onset seizures. Although the most frequent side effects of gabapentin are associated with the central nervous system, gabapentin can also affect the cardiovascular system.

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Ebook "Herbal products: Toxicology and clinical pharmacology" builds upon the informative foundation laid by its predecessor. This fully revised and expanded second edition boasts over 200 new references that document efficacy studies and adverse effects and four new chapters devoted to dietary products. Practitioners and researchers will find that this volume is a comprehensive resource for objective clinical information about the potential uses, efficacy, and safety of herbal medicines.

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Efavirenz (EFV) therapeutic response and toxicity are associated with high inter-individual variability attributed to variation in its pharmacokinetics. Plasma concentrations below 1 μg/ml may result in virologic failure and above 4 μg/ml, may result in central nervous system adverse effects.

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Prescribed medication taken in conjunction with alcohol can cause adverse side effects and generally, older people are advised not to drink when they are taking other drugs. Problems caused by using alcohol and other drugs concurrently may include a diminished effect of the drugs in an individual who drinks regularly and the increased sensitivity to drugs conferred by malnutrition and severe liver damage, for example cirrhosis. Alcohol in moderate amounts can depress the rate of drug metabolism so that the action of some drugs is exaggerated, such as benzodiazipines.

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