Chemotherapeutic development strategies

Part 2 book "Antiparasitic and antibacterial drug discovery - From molecular targets to drug candidates" includes content: In search of trypanocidal drugs, trypanosomatid protein kinases as potential drug targets, chemotherapeutic development strategies for schistosomiasis, searching new antiparasitics in virtual space, chemical optimization of anthelmintic compounds – a case study,.... and other contents.

255p oursky04 14-09-2023 4 3   Download

Strongylid nematode infections may negatively affect both animal health and welfare, with deleterious consequences for livestock productivity. Many farmers in recent decades have relied on anthelmintics as the sole strategy of control, but the intensive use of these chemotherapeutics has led to the development of anthelmintic resistance (AR).

11p vidarwin 23-02-2022 11 1   Download

Cancer is a disease characterized by the continuous growth of cells without adherence to the rules that healthy normal cells obey. Carbonic anhydrase I and II (CA I and CA II) inhibitors are used for the treatment of some diseases. The available drugs in the market have limitations or side effects, which bring about the need to develop new drug candidate compound(s) to overcome the problems at issue.

35p tudichquannguyet 29-11-2021 5 1   Download

The overzealous and indiscriminate use of most of the synthetic fungicides has created different types of environmental and toxicological problems. Recently, in different parts of the world, attention has been paid towards exploitation of higher plant products as novel chemotherapeutants in plant protection. Pyrethroids, and neem products are well established commercially as botanical pesticides and recently some essential oils of higher plants and animals products have also been used as antimicrobials against diseases.

21p cothumenhmong3 22-02-2020 25 1   Download