Childhood brain tumors

In children, the central nervous system tumors are exceeded in incidence only by leukemia and are more common than any of the other malignancies of childhood. Childhood central nervous system tumors encompass a range of histologic varieties from the histologically benignappearing pilocytic astrocytoma to the extremely malignant-appearing glioblastoma multiforme and the undifferentiated primitive neuroectodermal tumors. Similarly, the biologic behavior of childhood brain tumors varies not only according to histology but also with location of the tumor and age.

518p vimeyers 29-05-2024 2 2   Download

Neuroblastoma (NB) is a childhood malignant tumor,50% of high-risk NB children still have recurrence, and the long-term survival rate is very low. NB tumors expressing high levels of BDNF/TrkB are associated with poor survival outcomes.In this study, we show that the trends of serum concentration of BDNF at different growth stages after birth, and explore the relationship with NB replase.

9p vioracle 29-09-2023 3 2   Download

Down’s syndrome is the most common chromosomal abnormality in humans. It has been associated with central nervous system tumors such as primary acute lymphoblastic leukemia and germinomas, but desmoplastic infantile astrocytoma has not yet been reported with Down’s syndrome.

9p vigamora 23-05-2023 5 2   Download

Medulloblastoma is the most common malignant brain tumor of childhood. Although the clinical outcome for medulloblastoma patients has improved significantly, children afflicted with the disease frequently suffer from debilitating side effects related to the aggressive nature of currently available therapy.

11p vijisoo2711 30-09-2020 12 0   Download

Cancer survival comes at a price: pediatric cancer survivors bear a high risk for a wide range of cognitive difficulties. Therefore, interventions targeting these difficulties are required. The aim of the present clinical trial is to extend empirical evidence about efficacy of cognitive and physical training in pediatric cancer survivors.

10p vibaku2711 22-07-2020 7 1   Download

Advances in the treatment of childhood brain tumors have significantly improved survival rates. With improved survival rates, long-term treatment-related toxicities have become important, and the resulting complications can affect patients’ emotion and behavior.

10p vivalanbo2711 19-03-2020 9 1   Download

There are two main types of brain cancer. Primary brain cancer starts in the brain. Metastatic brain cancer starts somewhere else in the body and moves to the brain. According to the American Brain Tumor Association, brain tumors are the most common of the solid tumors in children, and the second most frequent malignancy of childhood. Brain tumors are the second leading cause of cancer-related deaths in males under 40 and the second leading cause of cancer-related deaths in females under age 20.

17p yasuyidol 02-04-2013 44 4   Download