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Chronic obstructive pulmonary disease emphysema
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Establishment of a mouse model is important for investigating the mechanism of chronic obstructive pulmonary disease (COPD). In this study, we observed and compared the evolution of the pathology in two mouse models of COPD induced by cigarette smoke (CS) exposure alone or in combination with lipopolysaccharide (LPS).
10p
vijichoo2711
31-05-2021
16
1
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Chronic obstructive pulmonary disease (COPD) is a respiratory condition characterised by dyspnoea, excessive sputum production, chronic cough, bronchitis and emphysema. Functionally, exercise tolerance is poor for people with COPD and is linked to difficulty in performing daily tasks.
6p
vianthony2711
16-04-2021
9
1
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C-Kit + lung stem cells have been described in the human healthy lung. Their potential relation with smoking and/or chronic obstructive pulmonary disease (COPD) is unknown. The adult human lung contains a mixture of c-Kit+ cells, unlikely to be lung stem cells, which are independent of smoking status and/or presence of COPD.
7p
vimontana2711
05-04-2021
13
2
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Chronic obstructive pulmonary disease (COPD) with carbon dioxide retention is associated with a worsening clinical condition and the beginning of pulmonary ventilation decompensation. This study aimed to identify the factors associated with carbon dioxide retention.
9p
vimontana2711
05-04-2021
10
1
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The fractal dimension characterizing the cumulative size distribution of low attenuation area (LAA) clusters, identified with a fixed threshold such as − 950 Hounsfield Units (HU), on computed tomography (CT) sensitively detects parenchymal destruction in chronic obstructive pulmonary disease (COPD) even when the percent LAA (LAA%), a standard emphysema index, is unchanged.
10p
vimontana2711
05-04-2021
8
1
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The imbalance between proteases and antiproteases has been proposed to participate to the pathogenesis of chronic obstructive pulmonary disease (COPD) and emphysema. Gene level variation in different metalloproteinases, metalloproteinase inhibitors, and cytokines affecting them may contribute to this imbalance and destruction of the lung parenchyma.
10p
vimontana2711
05-04-2021
7
2
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Dynamic gas compression during forced expiration has an influence on conventional flow-volume spirometry results. The extent of gas compression in different pulmonary disorders remains obscure. Utilizing a flow plethysmograph we determined the difference between thoracic and mouth flows during forced expiration as an indication of thoracic gas compression in subjects with different pulmonary diseases characterized by limitations in pulmonary mechanics.
9p
vimontana2711
05-04-2021
15
2
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There is a need for agents that suppress inflammation and progression of chronic obstructive pulmonary disease. p38 mitogen-activated protein kinase (p38 MAPK) has been associated with this disorder, and several inhibitors of this cascade are in clinical trials for its treatment, but their efficacy and utility are unknown.
14p
vimontana2711
05-04-2021
9
2
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Technology offers opportunities to improve healthcare, but little is known about Internet use by COPD patients. We tested two hypotheses: Internet access is associated with socio-demographic disparities and frequency of use is related to perceived needs.
11p
vimontana2711
05-04-2021
8
1
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Chronic obstructive pulmonary disease (COPD) has been classically divided into blue bloaters and pink puffers. The utility of these clinical subtypes is unclear. However, the broader distinction between airway-predominant and emphysema-predominant COPD may be clinically relevant.
11p
vimontana2711
05-04-2021
8
2
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Increased small airway resistance and decreased lung elasticity contribute to the airflow limitation in chronic obstructive pulmonary disease (COPD). The lesion that corresponds to loss of lung elasticity is emphysema; the small airway obstruction is due to inflammatory narrowing and obliteration. Despite their convergence in altered physiology, different mechanisms contribute to these processes.
11p
vimontana2711
05-04-2021
12
1
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This study assessed the effects of ursolic acid (UA) on airway-vessel remodeling and muscle atrophy in cigarette smoke (CS)-induced emphysema rats and investigated potential underlying mechanisms.
11p
vimaine2711
26-03-2021
14
2
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Lung cancer is a frequent comorbidity of chronic obstructive pulmonary disease (COPD). However, the local risk of developing lung cancer related to regional emphysema distribution and clinical outcome has not been investigated. Our aim was to evaluate the impact of regional emphysema score (RES) on tumor location and prognosis in non-small cell lung cancer (NSCLC) patients.
9p
vimichigan2711
26-03-2021
8
2
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Emphysema and chronic obstructive pulmonary disease (COPD) are well known independent risk factors for lung cancer. However, the developmental mechanisms between emphysema/COPD and lung cancer remain unknown. The purpose of this study was to evaluate PD-L1, FGFR1, PIK3CA, PTEN, and p16 expression in squamous cell carcinoma (SCC) associated with emphysema/COPD.
7p
vimaine2711
26-03-2021
10
2
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Chronic obstructive pulmonary disease (COPD) is a spectrum of airway diseases that has chronic bronchitis at one end and emphysema at other end. COPD is the major cause of morbidity and mortality worldwide. Most of the episodes (80%) of AECOPD are triggered by infections mainly affecting the lower respiratory tract by respiratory viruses, atypical bacteria and aerobic Gram positive and Gram negative bacteria.
7p
quenchua2
15-12-2019
20
1
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(BQ) Continued part 1, part 2 of the document Pulmonary and cardiovascular radiology with thoracic imaging (Third edition) has contents: The trachea, chronic obstructive pulmonary disease and emphysema, diffuse cystic lung diseases, the pleura and pleural disease,... and other contents. Invite you to refer.
1234p
thuongdanguyetan06
06-06-2019
16
1
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part 2 book “high-resolution ct of the lung” has contents: pulmonary edema and acute respiratory distress syndrome, emphysema and chronic obstructive pulmonary disease, cystic lung diseases, airways diseases, pulmonary hypertension and pulmonary vascular disease, drug-induced lung diseases and radiation pneumonitis,… and other contents.
391p
tieu_vu13
06-08-2018
29
1
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Objectives: To evaluate the results of one-way valve placement in treatment severe emphysema in chronic obstructive pulmonary disease. Subjects and methods: This study was a prospective, randomized clinical trial and carried out on 33 stable chronic obstructive pulmonary disease (COPD) patients with localized advanced emphysema.
11p
jangni3
20-04-2018
24
0
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Objectives: To identify the correlation between the severity of emphysema on chest CT with clinical characteristics, FEV1 and chest X-ray in stable COPD patients. Subjects: 112 COPD patients in stable stage, managed at the Respiratory Consultation Unit of Cantho Central Hospital.
7p
jangni3
20-04-2018
11
0
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