Clinical point
-
Multiple studies have indicated that patients with high body mass index (BMI) may have favourable survival outcomes following treatment with an immune checkpoint inhibitor (ICI). However, this evidence is limited by several factors, notably the minimal evidence from randomised controlled trials (RCTs), the use of categorised BMI with inconsistent cut point definitions, and minimal investigation of contemporary combination ICI therapy.
8p vishanshan 27-06-2024 1 1 Download
-
The rapid evolution, complexity, and specialization of oncology treatment makes it challenging for physicians to provide care based on the latest and best evidence. We hypothesized that physicians would use evidencebased trusted care pathways if they were easy to use and integrated into clinical workfow at the point of care.
8p vishanshan 27-06-2024 2 1 Download
-
Smoking is a major risk factor for multiple gastrointestinal cancers, and adversely affects peptic ulcer disease, gastroesophageal reflux, pancreatitis and Crohn’s disease. Despite key recommendations for diagnosing and treating tobacco use disorder in healthcare settings, the degree to which this is implemented in Gastroenterology (GI) clinics is unknown.
10p vishanshan 27-06-2024 1 1 Download
-
In healthcare, regulation of professions is an important tool to protect the public. With increasing regulation however, professions fnd themselves under increasing scrutiny. Recently there has also been considerable concern with regulator performance, with high profile reports pointing to cases of ineficiency and bias.
14p vishanshan 27-06-2024 1 1 Download
-
The result pointed out that only 5 g of soft tissue from N. glans (equivalent to 2–3 specimens) containing maximum toxicity detected in the present study may cause human death if consumed. Fhe first time, this study identified TTXs in the gastropods as a causative toxin in the poisoning in Vietnam. Moreover, 65.5% of studied specimens with high toxicity higher than 100 MU/g, including 16.1%, showing extremely high toxicity (> 1,000 MU/g). The results suggested that this gastropod is quite dangerous for human consumption and should be alerted to public awareness.
6p dianmotminh02 03-05-2024 3 1 Download
-
Ebook "Perinatal tissue-derived stem cells: Alternative sources of fetal stem cells" covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations.
246p tracanhphuonghoa1007 22-04-2024 3 2 Download
-
Ebook "Stem cell biology and regenerative medicine in ophthalmology" provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease.
196p cotieubac1004 15-03-2024 4 0 Download
-
Whole genome sequencing is increasingly being used for the diagnosis of patients with rare diseases. However, the diagnostic yields of many studies, particularly those conducted in a healthcare setting, are often disap‑ pointingly low, at 25–30%. This is in part because although entire genomes are sequenced, analysis is often confined to in silico gene panels or coding regions of the genome.
25p vicwell 29-02-2024 3 1 Download
-
We present a case of primary biliary cholangitis diagnosed during pregnancy. Diagnosis of this entity in pregnancy is infrequent, and when everything seemed to point to a simple obstetric cholestasis, close attention to the details of the clinical history was required to raise suspicion of the true diagnosis.
6p vigojek 02-02-2024 5 1 Download
-
Part 1 book "Point-of-care ultrasound techniques for the small animal practitioner" includes content: Introduction, basic ultrasound physics, basic ultrasound artifacts, basic ultrasound scanning, top ultrasound mistakes during global FAST, introduction and image acquisition, afast – clinical integration, liver and gallbladder, spleen, kidney, urinary bladder, gastrointestinal tract and pancreas,....and other contents.
574p oursky08 06-11-2023 8 3 Download
-
The TROIKA trial established that HD201 and trastuzumab were equivalent in terms of primary end-points (total pathological complete response) following neoadjuvant treatment. The objective of the present analysis was to compare survival outcomes and final safety.
9p vischultz 20-10-2023 1 1 Download
-
Part 1 book "A practical guide to fascial manipulation" includes content: History of fascial manipulation, anatomy of the fascia from the clinical point of view, physiology of the fascia from the clinical point of view.
108p oursky06 13-10-2023 7 3 Download
-
Pulmonary pleomorphic carcinoma is a very rare histological type of primary lung cancer, and usually provides aggressive clinical courses. A 65-year-old Japanese woman was diagnosed by transbronchial biopsy of the primary tumor as c-stage IV (cT4N3M1b) of adenocarcinoma harboring L858R point mutation in the exon 21 of epidermal growth factor receptor (EGFR).
5p viintuit 26-09-2023 3 0 Download
-
Part 1 book "Clinical applications pf PCR" includes content: A targeted Q-PCR-Based method for point mutation testing by analyzing circulating DNA for cancer management care, PCR-Based detection of DNA copy number variation, quantitative PCR for plasma epstein barr virus loads in cancer diagnostics,... and other contents.
90p oursky05 20-09-2023 3 1 Download
-
Part 1 of ebook "Veterinary laser therapy in small animal practice (First edition)" provides readers with content including: light’s actions in the body; light is just the catalyst; blood and light; anti-inflammatory effect; analgesic effect; tissue healing; pointing the light into the patient; light’s path to all these places in the body; pointing light at soft tissue: clinical applications; different flavors (frequencies) for different tissues;...
171p lytamnguyet 04-08-2023 6 2 Download
-
We created a system using a triad of change management, electronic surveillance, and algorithms to detect sepsis and deliver highly sensitive and specific decision support to the point of care using a mobile application. The investigators hypothesized that this system would result in a reduction in sepsis mortality.
8p visteverogers 24-06-2023 2 2 Download
-
To determine the effect of availability of clinical information from an integrated electronic health record system on pregnancy outcomes at the point of care. Materials and methods: We used provider interviews and surveys to evaluate the availability of pregnancyrelated clinical information in ambulatory practices and the hospital, and applied multiple regression to determine whether greater clinical information availability is associated with improvements in pregnancy outcomes and changes in care processes.
8p visteverogers 24-06-2023 5 3 Download
-
To better understand clinician information needs and learning opportunities by exploring the use of best-practice algorithms across different training levels and specialties. CPM usage varied widely across topics, specialties, and individual clinicians. Frequently viewed and recurrently viewed topics might warrant special attention. Specialists usually view topics within their specialty and may have unique information needs.
8p visteverogers 24-06-2023 3 2 Download
-
Many point-of-care laboratory tests are manually entered into the electronic health record by ambulatory clinic staff, but the rate of manual transcription error for this testing is poorly characterized. Using a dataset arising from a duplicated workflow that created a set of paired interfaced and manually entered point-of-care glucose measurements, we found that 260 of 6930 (3.7%) manual entries were discrepant from their interfaced result.
4p visteverogers 24-06-2023 4 3 Download
-
Decentralized privacy-preserving predictive modeling enables multiple institutions to learn a more generalizable model on healthcare or genomic data by sharing the partially trained models instead of patientlevel data, while avoiding risks such as single point of control. State-of-the-art blockchain-based methods remove the “server” role but can be less accurate than models that rely on a server.
12p visteverogers 24-06-2023 7 2 Download