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Clinical reporting
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The tripartite motif (TRIM) proteins have been reported to play crucial roles in various malignancies. However, the clinical significance of TRIM proteins in colorectal cancer (CRC) remains controversial. This study aimed to evaluate the association between TRIM proteins and the clinicopathological features and survival outcomes in patients with CRC.
9p
vishanshan
27-06-2024
1
1
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The impact of tumor-infiltrating neutrophils (TINs) on clinical outcomes has been reported in various cancer types, but their role in hepatocellular carcinoma (HCC) has not been fully evaluated. The aim of this study was to investigate the prognostic values for TINs in HCC patients undergoing curative resection.
8p
vishanshan
27-06-2024
1
1
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Nervous system toxicity (NST) is one of the most frequent and dangerous side effects of chimeric antigen receptor T-cell (CAR-T) therapy, which is an effective treatment for related tumors in most relapsed/refractory (r/r) hematologic malignancies. Current clinical trial data do not fully reflect the real-world situation. Therefore, this study evaluated the NST of CAR-T therapy using the FDA Adverse Event Reporting System (FAERS).
11p
vishanshan
27-06-2024
2
1
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Preclinical in vivo cancer models are essential tools for investigating tumor progression and response to treatment prior to clinical trials. Although treatment modalities are regularly assessed in mice upon tumor growth in vivo, surgical resection remains challenging, particularly in the orthotopic site. Here, we report a successful surgical resection of glioblastoma (GBM) in patient-derived orthotopic xenografts (PDOXs).
14p
vishanshan
27-06-2024
3
1
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Previous studies found that documentation of comorbidities differed when Veterans received care within versus outside Veterans Health Administration (VHA). Changes to medical center funding, increased attention to performance reporting, and expansion of Clinical Documentation Improvement programs, however, may have caused coding in VHA to change.
8p
vishanshan
27-06-2024
1
1
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Patient-centred measurement (PCM) emphasizes a holistic approach wherein the voices of patients are reflected in the standardized use of patient-reported outcome and experience measures and are represented throughout the continuum of measurement activities. Given the challenges of routinely integrating patient self reports into clinical care decisions, the perspectives of all healthcare system stakeholders, especially patients, is necessary to advance the science of PCM.
13p
vishanshan
27-06-2024
1
1
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Patient-centredness has become a central quality indicator for oncology care. Elements include shared decision-making, patient navigation and integration of psychosocial care, which impact patient-reported and clinical outcomes. Despite efforts to promote patient-centred care in Germany in recent decades, implementation remains fragmented.
10p
vishanshan
27-06-2024
2
1
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In healthcare, regulation of professions is an important tool to protect the public. With increasing regulation however, professions fnd themselves under increasing scrutiny. Recently there has also been considerable concern with regulator performance, with high profile reports pointing to cases of ineficiency and bias.
14p
vishanshan
27-06-2024
1
1
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To compare the diagnostic performance of the Node-RADS scoring system and lymph node (LN) size in preoperative LN assessment for rectal cancer (RC), and to investigate whether the selection of size as the primary criterion whereas morphology as the secondary criterion for LNs can be considered the preferred method for clinical assessment.
13p
vikoch
27-06-2024
1
1
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Our aim was to develop a validated Patient Reported Experience Measure (PREM) to capture patient and carer experience during participation in experimental cancer medicine trials (ECM): called PREM-ECM.
14p
vikoch
27-06-2024
3
1
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Genitourinary sarcomas are rare in adults and few large-scale studies on adult genitourinary sarcoma are reported. We aimed to elucidate the clinical characteristics, survival outcomes, and prognostic factors for overall survival of adult genitourinary sarcoma in Japan.
6p
vikoch
27-06-2024
1
1
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EGFR inhibitor and immunotherapy have been approved for adjuvant treatment in resectable nonsmall cell lung cancer (NSCLC). Limited reports of molecular and clinical characteristics as prognostic factors in NSCLC have been published.
14p
vikoch
27-06-2024
3
1
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There are limited and no standard therapies for recurrent glioblastoma. We herein report the antitumour activity and safety of sintilimab, bevacizumab and temozolomide (TMZ) in recurrent glioblastoma.
10p
vikoch
27-06-2024
1
1
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Isodicentric Y is one of the most common structural abnormalities of the Y chromosome. It is unstable during cell division, can generate various types of cell lines. Most reported patients are chromosomal mosaics, generally including a 45,X cell line.
6p
vicarlos
11-06-2024
1
0
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Various textbooks on stereotactic neurosurgery have been published during the last few years (Riechert 1980, Schaltenbrand and Walker 1982, Spiegel 1982), all of them dealing with functional stereo tactics as the major subject in the field. Diagnostic and therapeutic stereotactic interventions are only briefly described, whereas localization techniques are not yet mentioned. Since 1980, however, an increasing number of reports has been published on CT guided and computer monitored stereotactic performances which enable the surgeon to combine diagnostic and therapeutic efforts in one session.
290p
vimeyers
29-05-2024
2
2
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Duodenal diverticulum is a relatively common finding that can be incidentally found in upper gastrointestinal endoscopy in up to 20% of cases. Most duodenal diverticula are asymptomatic, and perforation of a duodenal diverticulum is extremely rare.
4p
viambani
21-05-2024
3
1
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To describe some clinical characteristics of adult patients with closed proximal humerus fracture (PHF), treated by osteosynthesis method with locking plate. Subjects and methods: Adult patients who were closed PHF treated by open reduction and locking plate fixation at Military hospital 175. Report of a retrospective study conducted on 42 clinical cases.
5p
vicarlos
16-05-2024
3
1
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Soft tissue defects in the calcaneal region represent a reconstructive challenge because of their complexity and the lack of local flaps. We report a clinical case of using the medial plantar free flap to cover of this area. The advantages of the flaps will be discussed.
4p
vijaychest
16-05-2024
1
1
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In particular, immuno-histopathological analysis of biopsies sample from breast tumor showed an overexpressing of vimentin marker (68.1%) in cells which indicated status of malignant metastasis. The metastatic tumor cells in breast tumor might cause the change in blood biochemical parameters together with sepsis, thus the dog was not eligible for surgery.
4p
visergey
02-04-2024
5
0
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A comprehensive understanding of cancer has been furthered with technological improvements and decreasing costs of next-generation sequencing (NGS). However, the complexity of interpreting genomic data is hindering the implementation of high-throughput technologies in the clinical context: increasing evidence on gene–drug interactions complicates the task of assigning clinical significance to genomic variants.
15p
vibransone
28-03-2024
3
2
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