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Clinical treatment strategy
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Breast cancer (BrCa) is a predominant malignancy, with metastasis occurring in one in eight patients, nearly half of which target the bone, leading to serious complications such as pain, fractures, and compromised mobility. This study aims to assess the efficacy of CTRA in monitoring osteolytic lesions’ progression and response to therapy, suggesting its potential superiority over existing methodologies in guiding treatment strategies.
13p
vishanshan
27-06-2024
1
1
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Predicting tumor responses to neoadjuvant chemotherapy (NAC) is critical for evaluating prognosis and designing treatment strategies for patients with breast cancer; however, there are no reliable biomarkers that can effectively assess tumor responses. Therefore, we aimed to evaluate the clinical feasibility of using extracellular vesicles (EVs) to predict tumor response after NAC.
12p
vikoch
27-06-2024
1
1
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Prevention, diagnosis and treatment are the watchwords in stroke research, for basic neuroscientists and clinicians alike. This 2002 book, from the 22nd Princeton Conference on Cerebrovascular Disease, contains contributions from outstanding investigators on numerous topics in stroke research. The contents cover the status and future directions of stroke pathophysiology, diagnosis and treatment, with special emphasis on the molecular and cellular mechanisms of ischaemic cell death and repair, and clinical issues including imaging, risk factors and therapeutic strategies in stroke.
456p
vimeyers
29-05-2024
4
2
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Ebook "Communicable diseases of the developing world" reviews the current strategies and challenges for the treatment of bacterial, fungal, parasitic and viral infectious diseases in developing countries. Contributing authors present expert analysis on the transmission, epidemiology, bacteriology, pathogenesis and treatment of Neglected Tropical Bacterial Diseases such as Leprosy, Buruli ulcer, and Trachoma. Particular attention is also given to current antifungal agents, their spectrum of activity, mode of action, limitations, and current challenges in antifungal therapy.
258p
tracanhphuonghoa1007
22-04-2024
5
3
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Ebook "Male infertility: Contemporary clinical approaches, andrology, ART & antioxidants" offers a comprehensive review of well-established, current diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based resource incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies involving antioxidants for male infertility.
511p
cotieubac1004
15-03-2024
7
0
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Ebook "Antibiofilm agents: From diagnosis to treatment and prevention (Volume 8)" provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections.
495p
manmanthanhla0201
26-02-2024
2
1
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Ebook "Photodynamic therapy: From theory to application" brings attention to an exceptional treatment strategy, which until now has not achieved the recognition and breadth of applications it deserves. The authors, all experts and pioneers in their field, discuss the history and basic principles of PDT, as well as the fundamentals of the theory, methods, and instrumentation of clinical diagnosis and treatment of cancer.
317p
nhanphanguyet
28-01-2024
5
2
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Part 2 book "Handbook of foodborne diseases" includes content: Plesiomonas, proteus, pseudomonas, salmonella, serratia, shigella - insights into the clinical features, pathogenesis, diagnosis, and treatment strategies, vibrio, yersinia candida, debaryomyces, encephalitozoon, enterocytozoon, mucor and mucormycosis, saccharomyces cerevisiae, acanthamoeba castellanii, balantidium coli; blastocystis,... and other contents.
346p
muasambanhan04
11-01-2024
9
1
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Ebook "Hepatitis B virus: Methods and protocols" details protocols and techniques ranging from cell culture studies to in vivo and clinical immunology. The chapters in this book discuss treatments of in vitro infection systems, analysis and quantification of cccDNA and its mutations; in vitro polymerase activity assays; cellular trafficking of core proteins; intracellular calcium metabolism; detection, cloning, and sequencing of HBV markers; and new strategies aimed at exploiting new mechanisms for drug discovery.
301p
lucchinguyen
28-12-2023
5
2
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Nutritional support, including nutritional counseling and oral nutritional supplements (ONS), has been recommended as a first-line strategy in patients with non-small cell lung cancer (NSCLC). Evidence on the efficacy of immunonutrition during immunotherapy in these patients is positive, but still limited some secondary endpoints, such as treatment toxicity and tolerance.
10p
vileonardodavinci
23-12-2023
4
2
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This study aimed to develop an innovative inflammation-nutrition biomarker score (INS) system to stratify the prognoses of patients with cancer. The INS system based on inflammation and nutrition biomarkers is a simple and effective prognostic stratification tool for patients with cancer, which can provide a valuable reference for clinical prognosis assessment and treatment strategy formulation.
9p
vileonardodavinci
23-12-2023
7
2
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We compared the clinical characteristics and survival outcomes after radical radiotherapy between nasopharyngeal carcinoma (NPC) with early and late metastases based on a relatively large cohort, which provides valuable data for the planning of clinical surveillance strategies.
9p
vileonardodavinci
23-12-2023
10
2
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Currently, main treatment strategies for early-stage non-small cell lung cancer (ES-NSCLC) disease are surgery or stereotactic body radiation therapy (SBRT), with successful local control rates for both approaches.
7p
vileonardodavinci
23-12-2023
2
2
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Novel strategies are needed to combat multidrug resistance in pancreatic ductal adenocarcinoma (PDAC). We applied genomic approaches to understand mechanisms of resistance in order to better inform treatment and precision medicine. Altered function of chromatin remodeling complexes contribute to chemoresistance.
14p
vileonardodavinci
23-12-2023
6
2
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Estrogen receptor-positive and progesterone receptor-negative (ER+/PR-) breast cancer comprise a special type. More than 10% breast cancer patients belonged to ER+/PR-. In this study, we identified the clinical and genetic characteristics of ER+/PR- breast cancer patients in China. Distinct PR statuses indicated different biological processes of ER+breast cancer and survival outcomes. Future treatment strategies may need to be tailored for ER+/PR- patients.
11p
vileonardodavinci
23-12-2023
6
2
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Shared decision-making has become of increased importance in choosing the most suitable treatment strategy for early rectal cancer, however, clinical decision-making is still primarily based on physicians’ perspectives. Balancing quality of life and oncological outcomes is difficult, and guidance on patients’ involvement in this subject in early rectal cancer is limited.
13p
vileonardodavinci
23-12-2023
6
4
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Brain metastases (BMs) are the most frequent intracranial tumours associated with poor clinical outcomes. Radiotherapy is essential in the treatment of these tumours, although the optimal radiation strategy remains controversial. The present study aimed to assess whether whole brain radiation therapy with a simultaneous integrated boost (WBRT + SIB) provides any therapeutic beneft over WBRT alone.
12p
vileonardodavinci
23-12-2023
6
3
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This study aims to analyse infuencing factors on health-related quality of life (HRQoL), such as treatment strategies, participation in a clinical trial and patient characteristics like anxiety, depression, gender, and age.
9p
vialfrednobel
23-12-2023
5
3
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Previous studies on cancer of unknown primary (CUP) mainly focus on treatment and prognosis in western populations and lacked clinical evaluation of different IHC markers, so this study aimed to evaluate characteristics of CUP and recommend a diagnostic strategy from a single center in China.
10p
vialfrednobel
23-12-2023
2
2
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Nanoliposomal irinotecan plus fluorouracil/leucovorin (5-FU/LV) is a standard second-line therapy for patients with pancreatic cancer. Identification of biomarkers is important to determine appropriate treatment strategies. We investigated the clinical practice outcomes and biomarkers associated with the nanoliposomal irinotecan plus 5-FU/LV regimen.
8p
vischultz
20-10-2023
3
1
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