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Collagen genes resulting
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Osteogenesis imperfecta (OI), commonly known as “brittle bone disease”, is an autosomal dominant disorder characterized by bone fragility and abnormalities in connective tissue. Biochemical and molecular genetic studies have shown that the vast majority of affected individuals have mutations in either the COL1A1 or COL1A2 genes that encode chains of type I procollagen.
7p
quenchua1
04-11-2019
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