Colorectal cancer epidemiology

The incidence of early-onset colorectal cancer (EOCRC, diagnosed in patients under the age of 50 years) has been increasing around the world. Here, we aimed to systematically identify distinctive features of EOCRC.

9p vishanshan 27-06-2024 2 1   Download

Challenges in colorectal cancer provides the most up-to-date information on the new and emerging treatments. The second edition looks at the total patient management of this condition and is aimed at the entire medical team caring for those with colorectal cancer. It also contains the latest guidelines on epidemiology and prevention of colorectal cancer, and the application of molecular genetics.

295p vimeyers 29-05-2024 2 2   Download

Heritable factors are well known to increase the risk of cancer in families. Known susceptibility genes account for a small proportion of all colorectal cancer cases. The aim of this study was to identify the genetic background in a family suggested to segregate a dominant cancer syndrome with a high risk of rectal- and gastric cancer.

8p vinarcissa 21-03-2023 3 1   Download

In Scotland colorectal cancer (CRC) is the third most common cancer and a leading cause of cancer death. Epidemiological studies have reported conflicting associations between statins and CRC risk and there is one published report of the association between statins and CRC survival.

10p viirene2711 03-10-2020 14 2   Download

Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are persistent environmental contaminants that affect metabolic regulation, inflammation, and other factors implicated in the development and progression of colorectal cancer (CRC).

15p vijennie2711 25-09-2020 63 1   Download

Over two decades ago, a proposal was that two different colorectal cancer (CRC) entities existed, based on tumour location either proximal (right) or distal (left) of the splenic flexure. Proximal and distal tumours exhibit different clinical, epidemiological, and biological characteristics

7p virose2711 22-09-2020 11 2   Download

Since the publication of two randomized controlled trials (RCT) in 1996 demonstrating the effectiveness of fecal occult blood test (FOBT) in reducing colorectal cancer (CRC) mortality, several public health initiatives have been introduced in Ontario to promote FOBT participation.

7p vilisa271 22-09-2020 7 0   Download

Recent epidemiological studies indicate the rate of gastrointestinal (GI) malignancies among younger patients is increasing, mainly due to colorectal cancer. There is a paucity of data regarding the magnitude of treatment-related symptoms, psychosocial issues and potential unmet needs in this population.

8p vimale2711 25-08-2020 6 1   Download

Venous thromoboembolism (VTE) is a frequent and burdensome complication of metastatic colorectal cancer (CRC). However, the epidemiology of VTE in patients with localized CRC after surgery in curative intent is incompletely understood.

8p vidhaka2711 31-07-2020 6 1   Download

Aspirin has been proposed as a novel adjuvant agent in colorectal cancer (CRC). Six observational studies have reported CRC-specific survival outcomes in patients using aspirin after CRC diagnosis but the results from these studies have been conflicting.

8p vibaku2711 22-07-2020 12 2   Download

Physical activity is consistently associated with a reduced risk of colorectal cancer in epidemiologic studies. This association among higher risk subgroups, such as those with a first-degree family history of colorectal cancer or high body mass index remains unclear.

15p vibaku2711 22-07-2020 17 2   Download

To revise the American Joint Committee on Cancer TNM staging system for colorectal cancer (CRC) based on a nomogram analysis of Surveillance, Epidemiology, and End Results (SEER) database, and to prove the rationality of enhancing T stage’s weighting in our previously proposed T-plus staging system.

9p vibaku2711 22-07-2020 13 2   Download

Surveillance, Epidemiology, and End Results (SEER) public research database does not include chemotherapy data due to concerns for incomplete ascertainment. To compensate for perceived lack of data quality many researchers use SEER-Medicare linked data, limiting studies to persons over age 65.

8p vibaku2711 22-07-2020 14 3   Download

Data on the long-term risks of non-AIDS defining cancers (NADCs) are limited, especially in Asians. The incidence of NADCs may correlate with the epidemiological trend of cancers or oncogenic infection in each country, and thus the target cancers would be different between Western and Asian countries.

9p vimanila2711 25-06-2020 10 0   Download

Epidemiological studies and cardiovascular prevention trials have shown that low-dose aspirin can reduce colorectal cancer (CRC) incidence and mortality, including inhibition of distant metastases.

9p viputrajaya2711 22-06-2020 13 1   Download

Approximately one third of all patients with CRC present with, or subsequently develop, colorectal liver metastases (CRLM). The objective of this population-based analysis was to assess the impact of resection of liver only, lung only and liver and lung metastases on survival in patients with metastatic colorectal cancer (mCRC) and resected primary tumor.

9p vijakarta2711 09-06-2020 9 1   Download

Recent data suggest that the risk of young-onset colorectal cancer (yCRC), in adults less than 50 years of age, is increasing. To confirm findings and identify contemporary trends worldwide, we conducted a systematic review of studies examining population-level trends in yCRC epidemiology.

14p vijakarta2711 09-06-2020 7 0   Download

(bq) “abc of colorectal cancer” has contents: epidemiology, molecular basis for risk factors, the role of clinical genetics in management, the role of primary care, primary treatment – does the surgeon matter, adjuvant therapy,… and other contents.

49p tieu_vu15 07-09-2018 20 2   Download

Document introduction of content: Introduction, methodology and literature review; epidemiology of colorectal cancer; screening tests and evidence - Stool tests, occult blood, and DNA; screening tests and evidence - Endoscopy and CT colonography, cost-Effectiveness of CRC screening; cascades – Tooling up for screening, where to get help, useful web sites, guidelines and selected references.

18p vovanvovan2013 13-05-2016 36 1   Download

The longer migrants live and adapt to their destination country, the more their cancer rates converge towards those in that country. This has been shown for stomach, colon and prostate cancer (McKay, 2003). Migrants from non-western countries to Europe were found to be more prone to cancers that are related to infections experienced in early life, such as liver, cervical and stomach cancer. In contrast, migrants of non-western origin were less likely to suffer from cancers related to a western lifestyle, e.g. colorectal and breast cancer (Arnold et al., 2010)....

550p ti_du_hoang 13-08-2012 60 7   Download