Combinatorial indexing

Ebook "The mathematics and topology of fullerenes (The mathematics and topology of fullerenes, Volume 04)" presents a comprehensive overview of scientific and technical innovations in theoretical and experimental studies.

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Ebook "The blood brain barrier (BBB)" covers all relevant aspects of drug research, e.g.

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Single-cell sequencing technologies are revolutionizing biology, but they are limited by the need to dissociate live samples. Here, we present ACME (ACetic-MEthanol), a dissociation approach for single-cell transcriptomics that simultaneously fixes cells. ACME-dissociated cells have high RNA integrity, can be cryopreserved multiple times, and are sortable and permeable.

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The recent boom in microfluidics and combinatorial indexing strategies, combined with low sequencing costs, has empowered single-cell sequencing technology. Thousands—or even millions—of cells analyzed in a single experiment amount to a data revolution in single-cell biology and pose unique data science problems.

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The practical use of graph-based reference genomes depends on the ability to align reads to them. Performing substring queries to paths through these graphs lies at the core of this task. The combination of increasing pattern length and encoded variations inevitably leads to a combinatorial explosion of the search space.

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The principle known as 'free indexation' plays an important role in the determination of the referential properties of noun phrases in the principleand-parameters language framework. First, by investigating the combinatorics of free indexation, we show that the problem of enumerating all possible indexings requires exponential time. Secondly, we exhibit a provably optimal free indexation algorithm. In (1), the pronominal "him" can be interpreted as being coreferential with "John", or with some other person not named in (1), but not with "Bill". ...

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Recent results have established that there is a family of languages that is exactly the class of languages generated by three independently developed grammar formalisms: Tree Adjoining Grammm~, Head Grammars, and Linear Indexed Grammars. In this paper we show that Combinatory Categorial Grammars also generates the same class of languages. We discuss the slruclm'al descriptions produced by Combinawry Categorial Grammars and compare them to those of grammar formalisms in the class of Linear Context-Free Rewriting Systems. ...

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Combinatory Categorial Grammars, CCGs, (Steedman 1985) have been shown by Weir and loshi (1988) to generate the same class of languages as Tree-Adjoining Grammars (TAG), Head Grammars (HG), and Linear Indexed Grammars (LIG). In this paper, I will discuss the effect of using variables in lexical category assignments in CCGs. It will be shown that using variables in lexical categories can increase the weak generative capacity of CCGs beyond the class of grammars listed above.

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Contents Techniques r Introduction to Algorithms r Data Structures and Sorting r Breaking Problems Down r Graph Algorithms r Combinatorial Search and Heuristic Methods r Intractable Problems and Approximations r How to Design Algorithms Resources r A Catalog of Algorithmic Problems r Algorithmic Resources References Index About this document

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Liver fibrosis ranks as the second cause of death in México's productive-age population. This pathology is characterized by acummulation of fibrillar proteins in hepatic parenchyma causing synthetic and metabolic disfunction. Remotion of excessive fibrous proteins might result in benefit for subjects increasing survival index. The goal of this work was to find whether the already known therapeutical effect of human urokinase Plasminogen Activator and human Matrix Metalloprotease 8 extends survival index in cirrhotic animals.

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