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Comparative evaluation
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Triple-negative breast cancer (TNBC) is a life-threatening subtype of breast cancer with limited treatment options. Therefore, this network meta-analysis (NMA) aimed to evaluate and compare the effect of various neoadjuvant chemotherapy (NCT) options on the long-term survival of patients with TNBC.
16p
vishanshan
27-06-2024
1
1
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Macroscopic vascular invasion (MVI) significantly impacts survival in patients with hepatocellular carcinoma (HCC), warranting systemic therapy over locoregional therapy. Despite novel approaches, HCC with MVI has a poor prognosis compared to early-to intermediate-stage HCC. This study aimed to evaluate the safety and efficacy of carbon-ion radiotherapy (C-ion RT) for HCC characterized by MVI.
9p
vishanshan
27-06-2024
2
1
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Dose-escalated radiotherapy is known to improve progression free survival in patients with localized prostate cancer, and recent advances have led to the standardization of ultrahypofractionated stereotactic ablative radiotherapy (SABR) delivered in just 5-fractions. This study aims to evaluate the safety, efficacy, and non-inferiority of generalizable 2-fraction SABR compared to the current 5-fraction regimen.
10p
vishanshan
27-06-2024
1
1
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The need for intelligent and effective treatment of diseases and the increase in drug design costs have raised drug repurposing as one of the effective strategies in biomedicine. There are various computational methods for drug repurposing, one of which is using transcription signatures, especially single-cell RNA sequencing (scRNAseq) data, which show us a clear and comprehensive view of the inside of the cell to compare the state of disease and health.
11p
vishanshan
27-06-2024
1
1
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Our findings demonstrate the presence of distinct metabolites in the serum of gastric cancer patients compared to healthy individuals. Lysophosphatidic acid, triglycerides, lysine, sphingosine1-phosphate, phosphatidylcholine, oxidized ceramide, and phosphatidylglycerol hold potential as biomarkers for evaluating postoperative efficacy and monitoring recurrence in gastric cancer patients.
12p
vishanshan
27-06-2024
1
1
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To explore challenges of liquid-based cytology (LBC) specimens for next-generation sequencing (NGS) in lung adenocarcinoma and evaluate the efficacy of targeted therapy. Methods A retrospective analysis was conducted on the NGS test of 357 cases of advanced lung adenocarcinoma LBC specimens and compared with results of histological specimens to assess the consistency. The impact of tumor cellularity on NGS test results was evaluated.
8p
vikoch
27-06-2024
1
1
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Anti-vascular endothelial growth factor monoclonal antibody (anti-VEGF) or immune checkpoint inhibitors (ICIs) combined with chemotherapy are commonly administered to cancer patients. Although cancer patients receiving anti-VEGF or ICIs have been reported to experience an increased risk of acute kidney injury (AKI), comparative studies on the AKI incidence have not been evaluated.
9p
vikoch
27-06-2024
1
1
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Novel antibody-drug conjugates (ADCs) drugs present a promising anti-cancer treatment, although survival benefits for HER2-positive advanced breast cancer (BC) remain controversial. The aim of this meta-analysis was to evaluate the comparative effect of ADCs and other anti-HER2 therapy on progression-free survival (PFS) and overall survival (OS) for treatment of HER2-positive locally advanced or metastatic BC.
10p
vikoch
27-06-2024
1
1
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Methylation of the promoters of SHOX2 and RASSF1A (LungMe®) exhibits promise as a potential molecular biomarker for diagnosing lung cancer. This study sought to assess the aberrant methylation of SHOX2 and RASSF1A in broncho-exfoliated cells (BEC) and compare it with conventional cytology, histology examination, immunohistochemistry, and serum tumor markers to evaluate the overall diagnostic efficiency for lung cancer.
14p
vikoch
27-06-2024
3
1
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This study aimed to investigate the role of chemo- and radiotherapy in the formation of tumor necrosis and to evaluate the influence of tumor necrosis on overall survival and local recurrence-free survival. Data from BS patients and patients who did not receive neoadjuvant therapy were compared.
9p
vikoch
27-06-2024
2
1
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Cemiplimab, a novel PD-1 inhibitor, exhibits significant antitumor activity against advanced non-small cell lung cancer (NSCLC). This study aimed to assess the cost-effectiveness of cemiplimab plus chemotherapy compared to chemotherapy for the treatment of advanced NSCLC, from the perspective of the United States payer.
11p
vikoch
27-06-2024
2
1
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The efficacy and safety of subxiphoid thoracoscopic thymectomy (SVATS) for early thymoma are unknown. The purposes of this meta-analysis were to evaluate the effectiveness and safety of SVATS for early thymoma, to compare it with unilateral intercostal approach video thoracoscopic surgery (IVATS) thymectomy, and to investigate the clinical efficacy of modified subxiphoid thoracoscopic thymectomy (MSVATS) for early anterior mediastinal thymoma.
13p
vikoch
27-06-2024
3
1
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The study aims to evaluate the safety of early - release radial compression time in patients with radial air-inflated pressure devices and to compare the efficacy of early - release radial compression time in patients with radial air - inflated pressure devices with standard methods.
6p
visergeyne
18-06-2024
0
0
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The rest of this paper is organized as follows: In Section 2, previous studies related to risk measure are mentioned in the literature. Section 3 presents research methodology including AS index and EPM methodology which are applied for evaluating all ETF funds performance. Then, the result and discussion between them are compared in section 4. The final section will conclude.
9p
leminhvu111
07-06-2024
0
0
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Ebook "Comparative evaluations of innovative fisheries management: Global experiences and European prospects" begins with a look at four places outside the European Union known for innovative management. Then the focus shifts to the success criteria related to specific disciplines including biological and social robustness, economic efficiency and impacts on management costs. Hypotheses are tested using data capable of generating useful results.
285p
giangdongdinh
28-05-2024
2
1
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"Numerical modeling of creep concrete beam and slab with boltzmann superposition principle" using this integral method, the creep model for Timoshenko beam and Mindlin plate will be evaluated by the Finite Element Method (FEM) combined Prony's series interpolation through MATLAB program. The creep datas used for Prony's series interpolation are based on international standards. These results obtained by FEM will be compared with available referred results and the results of the analytical method.
9p
dathienlang1012
03-05-2024
1
0
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In this study, three-dimensional crystal plasticity finite element method (CPFEM) simulations of the nanoindentation test on zinc single crystal have been implemented in the finite element code Abaqus using a user material subroutine. The basics of deformation mechanisms of zinc, nanoindentation test and crystal plasticity theory will be presented.
10p
dathienlang1012
03-05-2024
0
0
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This study is to evaluate the precision of some new global Earth Gravitational Models in the East Vietnam Sea, selecting the best model. The method and the program for calculating Free air gravity anomaly from the global earth gravitational model have been researched and developed. Evaluation of the precision of the models is done by comparing the models with ship-derived gravity anomalies. Data with anomalous signs are detected and removed when the deviation exceeds three times the root mean square deviation.
13p
dianmotminh02
03-05-2024
1
1
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The outcomes are to be compared with typical drugs given that compounds are examined against gram-positive and gram-negative strains of bacteria and fungus. Against bacterial strains, products with nitro, methyl, and bromo substituents in the p-position of the benzene ring, as well as products with the nitro group at the m-position, showed very excellent activities against bacterial strains, while compounds with chloro substituent at p-position and m-position demonstrated good activity against the fungal strains Aspergillus niger and Fusarium javanicum.
8p
dianmotminh02
03-05-2024
2
1
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In this study, we evaluated and compared the effectiveness of four different protocols (D, MJ, MA, and S) for separating MPs from water of different types (brackish, marine, and river). Known combinations of MP particles (polyethylene (PE), polyethylene terephthalate (PET), polystyrene (PS) and polyvinyl chloride (PVC) with size ranging between 150 μm and 700 μm were spiked into water samples. Our results showed that the average recovery effectiveness of microplastics using four studied methods ranged from 53% to 86%.
10p
dianmotminh02
03-05-2024
2
1
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