Compounded growth

his study focused on finding alkaloid compounds collected from Chemfaces database that inhibit HER2 enzyme employing computational methods such as molecular docking and ADMET prediction. Out of 118 phytochemicals docked to the ATP binding site of the HER2 kinase domain, 10 alkaloid compounds exhibited higher binding affinity than the reference inhibitor and satisfied the Lipinski’s rule of five. All compounds have good pharmacokinetic properties.

10p dianmotminh02 03-05-2024 4 3   Download

Epidermal growthfactor receptor(EGFR) and human epithelium receptor-2(HER2) are members of the epidermal growth factor receptor (EGFR/ErbB) family implicated in the development of many types of carcinoma. Zanthoxylum simulans Hance has the effect of inhibiting growth and causing the death of many types of cancer cells. In this study, the molecular docking method and molecular dynamics simulations were used to evaluate the inhibition abilities of EGFR and HER2 receptors of 120 compounds in Zanthoxylum simulans Hance.

12p dianmotminh02 03-05-2024 3 2   Download

Ebook "Structure-property relationships in non-linear optical crystals II: The IR region" is devoted to the IR region with four review-type chapters that were written by five of our faculty members who are the leading scientists in their field. Prof. G.-C. Guo reviews the crystal growth of large crystals and new mid-infrared second-order NLO pnictide, chalcogenide, and halide materials. Prof. K.-C. Wu discusses the simulation and design of IR second-order NLO metal cluster compounds...

151p coduathanh1122 27-03-2024 4 1   Download

Ebook "Salt stress in plants: Signalling, omics and adaptations" will shed light on the effect of salt stress on plants development, proteomics, genomics, genetic engineering, and plant adaptations, among other topics. The book will cover around 25 chapters with contributors from all over the world. ​​The interactions of salts with mineral nutrition may result in nutrient imbalances and deficiencies. The consequence of all these can ultimately lead to plant death as a result of growth arrest and molecular damage.

517p manmanthanhla0201 26-02-2024 5 1   Download

Ebook "Wine microbiology: Practical applications and procedures" addresses real world problems such as characterization and enumeration of yeast, bacteria and molds common to juice and wine environments and their impact on wine quality and stability. In addition, the potential of solving processing problems through rapid, real-time molecular methods and new applications for using starter cultures of non-Saccharomyces yeast are discussed. The book is a great resource for professionals and students in the field of enology and viticulture.

408p manmanthanhla0201 27-02-2024 4 2   Download

Part 2 book "Fundamentals of solid state engineering" includes content: Semiconductor P-N and metal semiconductor junctions; optical properties of semiconductors; solar energy harvesting; thermal and photothermal energy harvesting; photo thermovoltaics; electron electron interactions - screening; semiconductor heterostructures and low dimensional quantum structures; quantum transport; compound semiconductors and crystal growth techniques; semiconductor characterization techniques; defects.

365p muasambanhan06 03-02-2024 5 1   Download

Ebook "Plant biotechnology for health: From secondary metabolites to molecular farming" emphasis will be put in the relevance of Plant Biotechnology for producing compounds of pharmaceutical and industrial relevance specifically the contribution of in vitro plant cell cultures for producing recombinant proteins (molecular farming) and compounds produced by plants useful for human and animal health (secondary metabolites) will be discussed.

174p nhanphanguyet 28-01-2024 3 2   Download

Ebook "Sulfur assimilation and abiotic stress in plants" discusses the aspects of sustainable crop production with sulfur, the importance of sulfur metabolites and sulfur metabolizing enzymes in abiotic stress management in plants. Sulfur is one of the four major essential elements necessary for the plant life cycle. Its assimilation in higher plants and its reduction in metabolically important sulfur compounds are crucial factors determining plant growth and vigor and resistance to stresses.

373p tachieuhoa 28-01-2024 3 2   Download

Ebook "Prokaryotic cell wall compounds: Structure and biochemistry" provides an up-to-date knowledge of the prokaryotic cell wall, including its structure, composition, synthesis, assembly, and some surface interactions. Topics concerning bacterial and archaeal polymeric cell wall structures, biological activities, growth and inhibition, cell wall interactions and the applications of cell wall components, especially in the field of nanobiotechnology, are presented.

518p tachieuhoa 28-01-2024 5 2   Download

Ebook "Plant growth and health promoting bacteria" to cope with the increasing problems created by agrochemicals such as plant fertilizers, pesticides and other plant protection agents, biological alternatives have been developed over the past years. These include biopesticides, such as bacteria for the control of plant diseases, and biofertilizer to improve crop productivity and quality.

453p tachieuhoa 28-01-2024 7 3   Download

The optimal duration of anti-PD-1 for cancer therapy has not been tested, especially when using combination therapy. Epidermal growth factor receptor (EGFR) pathway blocker was the top compound that enhanced T-cell killing of tumor cells in a high-throughput immune-oncology screen, possibly by stimulate the antigen presentation machinery and other mechanisms.

9p vileonardodavinci 23-12-2023 2 2   Download

Ebook "Key concepts in accounting and finance" is one of a range of comprehensive glossaries with entries arranged alphabetically for easy reference. All major concepts, terms, theories and theorists are incorporated and cross-referenced. Additional reading and Internet research opportunities are identified. More complex terminology is made clearer with numerous diagrams and illustrations.

271p tuongnhuoclan 28-11-2023 7 5   Download

This study aimed to quantify the phenolic contents and the antioxidant capacities of leaf extract powders from three Myrtaceae plants, namely Cleistocalyx operculatus (Vietnamese name: Vối), Psidium guajava (Ổi), and Rhodomyrtus tomentosa (Sim), investigate their inhibitive activities on the growth of bacteria isolated from spoiled shrimps, and evaluate their values as preservative agents in the cold storage of Pacific whiteleg shrimps (Penaeus vannamei).

15p viengels 25-08-2023 7 2   Download

The current experiment aimed to determine the effects of peptidoglycan, known as a prebiotic compound, on the growth, feed efficiency, and disease resistance in Nile tilapia. Fish at an initial body weight of 22.6 ± 0.3g were distributed into a 100 L-glass tank system.

10p viengels 25-08-2023 7 2   Download

The induced magnetic properties and the interaction between the electrons in the valence and the conduction bands affect the positions of the energy band and the band-gap in DMS. The growth technology of DMS is quite sophisticated and the magnetic properties mainly depend on the impurity concentrations of the properly grown multicomponent compounds.

6p viberbers 09-08-2023 5 4   Download

After completing this chapter, students will be able to: Extend the analysis of trade beyond the traditional static models of international trade and analyze the relationship between international trade and economic growth; show how the power of compounding makes international trade’s effect on economic growth much more important for human welfare than the static gains in welfare;...

15p haojiubujain04 27-07-2023 6 3   Download

Melatonin (MT) is considered as a plant growth regulator, has extensive functions and plays a prominent role in ripening and fruit senescence. However, there has been no report regarding the influence of melatonin on biochemical changes of avocado fruit (Persea americana Mill.) during ripening.

10p vicaptainmarvel 21-04-2023 4 2   Download

Endophytic fungi, microfungi that internally infect living plant tissues, are reported to have the ability to synthesize many enzymes, plant growth hormones and pharmaceutically active compounds similar to those in their hosted plants. This has opened a potential path of using endophytic fungi as a bioreactor for mass production of bioactive compounds at a lower cost.

10p vicaptainmarvel 21-04-2023 6 2   Download

Quinazoline derivatives are a class of important antitumor drugs known as small molecule inhibitors that include epidermal growth factor receptor (EGFR) inhibitors. Based on the structure of poziotinib, a series of 6-aryloxyl substituted quinazoline derivatives were designed and synthesized. The molecular docking results suggested that compound 4m has different binding modes to the wild-type and mutated EGFR.

37p lyhuyenthu 31-01-2023 4 2   Download

As part of a research aiming at the isolation of bacteria secreting growth-inhibiting compounds, cultures of Francisella tularensis were implanted in environmental samples and monitored for inhibition zones on agar.

4p vihagrid 30-01-2023 13 3   Download