Compounds from culture broth

Ophiocordyceps sinensis (O. sinensis) – commonly known as Dong Chong Xia Cao, is a medicinal fungus that contains valuable bioactive compounds such as cordycepin, polysaccharide…,in which, the exopolysaccharide (EPS) obtained from the cultured medium is a polysaccharide that has been convinced to have various bioactivities such as antioxidant, antibacterial, etc.

8p vipriyankagandhi 27-07-2022 4 2   Download

Seven compounds were isolated and characterized from the culture broth of the marine bacteria Nocardiopsis sp. (strain G057), which was isolated from sediment collecting at Cô Tô – Quảng Ninh. Their structures were determined by spectroscopic analysis including MS and 2D NMR, as well as by comparison with reported data in the literature. All compounds were evaluated for their antimicrobial activity against a panel of clinically significant microorganisms. Compounds 1, 2 and 7 selectively inhibited Escherichia coli with a MIC value of 32, 64, 8 μg/mL, respectively.

5p cothumenhmong11 10-05-2021 8 1   Download

Five secondary metabolites including three flavonoids, 6-lavandulyl-5,7,2′,4′-tetrahydroxyflavanone (1), 5′- lavandulyl-2′-methoxy-2,4,4′,6′-tetrahydroxychalcone (2), 6-lavandulyl-7-methoxy-5,2′,4′-trihydroxyflavanone (3), and two alkaloids, tryptoline (4), and norharman (5) were isolated from the culture broth of Streptomyces sp. C011. Their structures were determined by spectral data analysis, including MS, 2D NMR, and CD spectrum. All the separated compounds were evaluated for their antimicrobial activities. Compounds 1, 2, 3 and 5 exhibited antimicrobial activity...

5p cothumenhmong11 06-05-2021 13 2   Download

In a recent study, we described two new lavandulylated flavonoids, along with eight known compounds from the culture broth of a Streptomyces sp. (strain G246), isolated from the sponge Halichondria panicea, collected in the sea of Son Tra peninsula (Da Nang). A comparison study was conducted to differentiate between solid and liquid fermentation technique for secondary metabolites production of strain G246. In this paper, we report the isolation and structural characterization of nine secondary metabolites (1-9) from strain G246 by solid state fermentation.

8p nguaconbaynhay10 19-02-2021 12 2   Download

Five compounds L-phenyl alanine (1), 1-methyl-6-acetyl-α-D-glucopyranoside (2), thymine (3), uracil (4), and (2R,3S)-butane-2,3-diol (5) were isolated and characterized from the culture broth of the marine bacterium Micromospora sp. (G047 strain), which was isolated from the sediment collecting from the coast of Co To – Quang Ninh. The structures of all isolates were determined by spectroscopic analysis including MS and 2D NMR, as well as by comparison with reported data in the literature.

4p giesumanh 10-11-2018 31 1   Download

Nine compounds (1-9) were isolated and characterized from the culture broth of the marine bacteria Micromonospora sp. (strain G068), which was isolated from sediment collected at Co To – Quang Ninh. Their structures were determined by spectroscopic analysis including MS, 1D NMR and 2D NMR, as well as by comparison with reported data in the literature. All compounds were evaluated for their antimicrobial activities against a panel of . Compounds 1, 6, and 9 selectively inhibited Escherichia coli with MIC values of 128, 128 and 64 μg/mL, respectively.

7p cumeo3000 01-08-2018 23 0   Download