Comprehensive treatment

Rectal cancer treatment has transformed in recent years, with neoadjuvant treatment (NT) and total neoadjuvant treatment (TNT) aiming to enhance pathological responses. This pioneering study in our country delves into rectal cancer management, offering crucial insights by examining pathological outcomes in patients treated with the NT and TNT approach, shaping the evolving landscape.

9p vishanshan 27-06-2024 1 1   Download

The need for intelligent and effective treatment of diseases and the increase in drug design costs have raised drug repurposing as one of the effective strategies in biomedicine. There are various computational methods for drug repurposing, one of which is using transcription signatures, especially single-cell RNA sequencing (scRNAseq) data, which show us a clear and comprehensive view of the inside of the cell to compare the state of disease and health.

11p vishanshan 27-06-2024 1 1   Download

Guidance on tailored precision therapy with consideration of genomic mutations was possible for some patients with information provided by F1CDx. Clinicians should consider using F1CDx at turning points in the course of the disease.

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The influence of mobility and travel distance on access to BC care is multifaceted and should consider the complex interplay of geographic barriers, sociodemographic factors, health system issues, and policy-related challenges. Further research is needed to comprehensively understand the variables impacting access to health services, particularly in LATAM countries, where the challenges women face during treatment remain understudied.

11p vishanshan 27-06-2024 1 1   Download

Radiotherapy delivery regimens can vary between a single fraction (SF) and multiple fractions (MF) given daily for up to several weeks depending on the location of the cancer or metastases. With limited evidence comparing fractionation regimens for oligometastases, there is support to explore toxicity levels to nearby organs at risk as a primary outcome while using SF and MF stereotactic ablative radiotherapy (SABR) as well as explore differences in patient-reported quality of life and experience.

14p vikoch 27-06-2024 1 1   Download

An excellent reference for the experienced breast surgeon is now available in Plastic and reconstructive breast surgery: An atlas. It assumes that the reader has a solid foundation in plastic surgery and is familiar with various operative methods. It describes the complete range of breast surgery: augmentation and reduction mammaplasty, anomalies, the treatment of primary breast cancer and breast reconstruction.

200p vimeyers 29-05-2024 3 2   Download

This volume will be of value to research investigators and practitioners within the behavioral sciences and medicine. Critical and comprehensive reviews of the assessment, treatment, and prevention of medical disorders are provided. Thus, the volume will be especially useful for teaching purposes both within medical and university settings and will serve as a source ebook for scholars and practitioners.

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This book provides a comprehensive treatment of all aspects of local budgeting needed to develop sound fiscal administration such as setting priorities, planning, financial control over inputs, management of operations and accountability to citizens.

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This book is the first academic treatment of family business issues within the tourism and hospitality industry. It provides comprehensive assessment of ownership, management and family-related concerns across the entire business and family life cycle. Many new international case studies of real family businesses are used to illustrate key points. The book will be of significant interest to researchers and students in tourism and hospitality, small business and entrepreneurship studies, as well as to owners and potential investors in family businesses.

232p vimeyers 29-05-2024 7 1   Download

Ebook "Advanced agent-based environmental management systems" presents a comprehensive reference of state-of-the-art efforts. Specifically, it presents current and future ways in which adaptive information technologies, techniques, protocols and architectures, such as software agent technologies and multi-agent systems, can be used to support the development of real-world agent-based systems in the area of e-Environment.

174p giangdongdinh 28-05-2024 2 1   Download

This study addresses the elevated prevalence of skin and soft tissue infections (SSTIs) within the pediatric demographic, necessitating a comprehensive inquiry into their varied clinical manifestations. The primary objectives involve the assessment of clinical and laboratory characteristics of SSTIs in children and an exploration of their correlation with treatment efficacy.

5p viambani 21-05-2024 5 1   Download

Ebook "Notch signaling in embryology and cancer" is to comprehensively cover a highly readable overview on our present knowledge of the role of Notch signalling for embryology and cancer, with a focus on new findings in molecular biology. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in cellular and molecular pathology to new concepts for prophylaxis and treatment of cancer.

346p ladongphongthanh1008 22-04-2024 2 1   Download

Ebook "Cancer biology and the nuclear envelope: Recent advances may elucidate past paradoxes" presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer.

610p tracanhphuonghoa1007 22-04-2024 2 1   Download

This study investigates the impact of karaoke activities on English pronunciation by engaging 27 English major students in five karaoke-based pronunciation learning sessions. Both pretests and posttests, along with survey questionnaires and interviews, were employed to assess changes in participants' pronunciation competency before and after the treatment.

9p vilarry 01-04-2024 3 0   Download

A comprehensive understanding of cancer has been furthered with technological improvements and decreasing costs of next-generation sequencing (NGS). However, the complexity of interpreting genomic data is hindering the implementation of high-throughput technologies in the clinical context: increasing evidence on gene–drug interactions complicates the task of assigning clinical significance to genomic variants.

15p vibransone 28-03-2024 3 2   Download

Gastric cancer is among the most lethal human malignancies. Previous studies have identified molecular aberrations that constitute dynamic biological networks and genomic complexities of gastric tumors. However, the clinical translation of molecular-guided targeted therapy is hampered by challenges. Notably, solid tumors often harbor multiple genetic alterations, complicating the development of effective treatments.

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Tumor cell-intrinsic mechanisms and complex interactions with the tumor microenvironment contribute to therapeutic failure via tumor evolution. It may be possible to overcome treatment resistance by developing a personalized approach against relapsing cancers based on a comprehensive analysis of cell typespecific transcriptomic changes over the clinical course of the disease using single-cell RNA sequencing (scRNA-seq).

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Gastric cancer (GC) is a heterogenous disease consisted of several subtypes with distinct molecular traits. The clinical implication of molecular classification has been limited especially in association with treatment efficacy of ramucirumab or various targeted agents.

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Ebook "Environmental analysis by electrochemical sensors and biosensors - Volume 1: Fundamentals" presents an exhaustive overview of electrochemical sensors and biosensors for the analysis and monitoring of the most important analytes in the environmental field, in industry, in treatment plants and in environmental research. The chapters give the reader a comprehensive, state-of-the-art picture of the field of electrochemical sensors suitable to environmental analytes, from the theoretical principles of their design to their implementation, realization and application.

714p tudohanhtau1006 29-03-2024 2 1   Download

Ebook "Isoconversional kinetics of thermally stimulated processes" is to create the first comprehensive resource on the theory and applications of isoconversional methodology. The book introduces the reader to the kinetics of physical and chemical condensed phase processes that occur as a result of changing temperature and discusses how isoconversional analysis can provide important kinetic insights into them. The book will help the readers to develop a better understanding of the methodology, and promote its efficient usage and successful development.

247p tudohanhtau1006 29-03-2024 8 1   Download