Computational biologists

Ebook "The gene ontology handbook" provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO.

298p tachieuhoa 28-01-2024 8 3   Download

Ebook "Data integration in the life sciences: 7th international conference, DILS 2010 Gothenburg, Sweden, August 25-27, 2010 proceedings" brings together data and knowledge management researchers from the computer science research community with bioinformaticians and computational biologists, to improve the understanding of how emerging data integration techniques can address requirements identified in the life sciences.

224p tachieuhoa 28-01-2024 6 2   Download

Ebook "Philosophy of systems biology: Perspectives from scientists and philosophers" features reflections and original work by experts from across the disciplines including systems biologists, philosophers, and interdisciplinary scholars investigating the social and educational aspects of systems biology. In response to the same set of questions, the experts develop and defend their personal perspectives on the distinctive character of systems biology and the challenges that lie ahead.

273p lucchinguyen 28-12-2023 4 2   Download

The recent shift of computational biologists from bioinformatics service providers to leaders of cutting-edge programs highlights the accompanying cultural and conceptual changes that should be implemented by funding bodies and academic institutions.

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Increasingly, biologists and biochemists use computational tools to design experiments to probe the function of proteins and/or to engineer them for a variety of different purposes. The most effective strategies rely on the knowledge of the three-dimensional structure of the protein of interest.

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The inference of homologies among DNA sequences, that is, positions in multiple genomes that share a common evolutionary origin, is a crucial, yet difficult task facing biologists. Its computational counterpart is known as the multiple sequence alignment problem.

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The rapid advancements in the field of genome sequencing are aiding our understanding on many biological systems. In the last five years, computational biologists and bioinformatics specialists have come up with newer, better and more efficient tools towards the discovery, analysis and interpretation of different genomic variants from high-throughput sequencing data.

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Over the last decade, next generation sequencing (NGS) has become widely available, and is now the sequencing technology of choice for most researchers. Nonetheless, NGS presents a challenge for the evolutionary biologists who wish to estimate evolutionary genetic parameters from a mixed sample of unlabelled or untagged individuals, especially when the reconstruction of full length haplotypes can be unreliable.

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Computational biologists daily face the need to explore massive amounts of genomic data. New visualization techniques can help researchers navigate and understand these big data. Horizon Charts are a relatively new visualization method that, under the right circumstances, maximizes data density without losing graphical perception.

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Histone modifications play important roles in gene regulation, heredity, imprinting, and many human diseases. The histone code is complex and consists of more than 100 marks. Therefore, biologists need computational tools to characterize general signatures representing the distributions of tens of chromatin marks around thousands of regions.

18p viconnecticut2711 28-10-2020 11 0   Download

With its highly developed capacity to detect patterns in data, Perl has become one of the most popular languages for biological data analysis. But if you're a biologist with little or no programming experience, starting out in Perl can be a challenge. Many biologists have a difficult time learning how to apply the language to bioinformatics. The most popular Perl programming books are often too theoretical and too focused on computer science for a non-programming biologist who needs to solve very specific problems....

394p hoa_can 28-01-2013 63 10   Download

This book was conceived as a result of many years research with students and postdocs in molecular simulation, and shaped over several courses on the subject given at the University of Groningen, the Eidgen¨ossische Technische Hochschule (ETH) in Z¨urich, the University of Cambridge, UK, the University of Rome (La Sapienza), and the University of North Carolina at Chapel Hill, NC, USA.

626p camnhung_1 13-12-2012 60 11   Download

Knowing nature is a complex, multiple, and highly political process. This is clearly illustrated by looking at the knowledge and management of a piece of land, seemingly isolated but impacting and impacted by decision- making processes, politics, and technology around the world. A barren stretch of ground in the Sahelian region of West Africa holds diverse meanings to different people and institutions. Livestock herders value it for its proximity to a water point and for the grass it will grow once the rains come.

374p camchuong_1 11-12-2012 69 3   Download

The handbook is written for mature readers with a great deal of rigorous experience with either doing scientific research or writing scientific software. However no specific background in computer science, statistics, or biology is required to understand most of the chapters. In order to accommodate the readers who wish to become professional computational biologists in the future we also provide appendices that contain educationally sound glossaries of terms and descriptions of major sequence analysis algorithms.

570p banhkem0908 24-11-2012 78 5   Download

This book is about how to construct and use computational models of specific parts of the nervous system, such as a neuron, a part of a neuron or a network of neurons. It is designed to be read by people from a wide range of backgrounds from the biological, physical and computational sciences. The word ‘model’ can mean different things in different disciplines, and even researchers in the same field may disagree on the nuances of its meaning.

0p taurus23 27-09-2012 46 6   Download

Bioinformatics is a growing multidisciplinary field of science comprising biology, computer science, and mathematics. It is the theoretical and computational arm of modern biology. In other words, bioinformatics is a tool in the hands of biologists for analyzing huge amount of biological data available on mainstream public databases. Currently, bioinformatics has gained variety of applications in agriculture, medicine, engineering, and natural science. This book discusses a small portion of these applications along with basic concepts and fundamental techniques in bioinformatics....

736p greengrass304 15-09-2012 91 15   Download

The biological sciences have become more quantitative and information-driven since emerging computational and mathematical tools facilitate collection and analysis of vast amounts of biological data. Complexity analysis of biological systems provides biological knowledge for the organization, management, and mining of biological data by using advanced computational tools. The biological data are inherently complex, nonuniform, and collected at multiple temporal and spatial scales.

316p chuyenphimbuon 21-07-2012 60 13   Download

Scientists at Michigan Stale University are asking a most challengrng question. Can a computQr program be considered alive? The members of the Digital Evolution Laboratory say yes. Computer scientists at the laboratory have created a program calted Avida that has intrigued not only scientists and engineers, but biologists and philosophers as wetl.

10p kathy206 30-07-2010 61 6   Download

Scientists at Michigan Slate University are asking a most challenging question. Can a computer program be considered alive? The members oi the Digital Evolution Laboratory say yes. Computer scientists at the laboratory have creaied a program called Avida that has intrigued not only scientists and engineers, but biologists and philosophers as well.

10p kathy206 30-07-2010 63 4   Download