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Computational predictor
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We aimed to identify preoperative predictors of aggressive pathology for cT1 solid renal cell carcinoma (RCC) by combining clinical features with qualitative and quantitative CT parameters, and developed a nomogram model.
13p
vikoch
27-06-2024
2
1
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Stopgain substitutions are the third-largest class of monogenic human disease mutations and often examined first in patient exomes. Existing computational stopgain pathogenicity predictors, however, exhibit poor performance at the high sensitivity required for clinical use.
11p
viellison
28-03-2024
3
2
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To quantify variation in public health system engagement with tribal organizations across a national sample of communities and to identify predictors of engagement. Social network analysis measures were computed to indicate the extent of tribal organization participation in public health networks and to understand the sectors and social services that engage with tribal organizations in public health activities. Two-part regression models estimated predictors of tribal engagement.
10p
vigamora
25-05-2023
4
2
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Advanced Computer Architecture - Lecture 16: Instruction level parallelism. This lecture will cover the following: correlating branch predictors; tournament predictor; high performance instruction delivery – branch target buffer; hardware intensive approaches; predictor increases misprediction rate;...
52p
haoasakura
30-05-2022
12
4
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Advanced Computer Architecture - Lecture 17: Instruction level parallelism. This lecture will cover the following: high-performance instructions delivery - multiple issue; high-performance processors; branch target buffer; integrated instruction fetch units; return address predictors; multiple instruction-issue processors;...
42p
haoasakura
30-05-2022
13
4
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Advanced Computer Architecture - Lecture 15: Instruction level parallelism. This lecture will cover the following: dynamic branch prediction; branch prediction buffer; examples of branch predictor; predicated execution can reduce number of branches, number of mispredicted branches;...
41p
haoasakura
30-05-2022
9
3
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Cell-penetrating peptides (CPPs) are short peptides (5–30 amino acids) that can enter almost any cell without significant damage. On account of their high delivery efficiency, CPPs are promising candidates for gene therapy and cancer treatment. Accordingly, techniques that correctly predict CPPs are anticipated to accelerate CPP applications in future therapeutics. Recently, computational methods have been reportedly successful in predicting CPPs. Unfortunately, the predictive performance of existing methods is not satisfactory and reliable so as to accurately identify CPPs.
11p
vilarryellison
29-10-2021
7
0
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Post-translational modification is considered an important biological mechanism with critical impact on the diversification of the proteome. Although a long list of such modifications has been studied, succinylation of lysine residues has recently attracted the interest of the scientific community. The experimental detection of succinylation sites is an expensive process, which consumes a lot of time and resources. Therefore, computational predictors of this covalent modification have emerged as a last resort to tackling lysine succinylation.
10p
vilarryellison
29-10-2021
9
0
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Identifying mRNA targets of miRNAs is critical for studying gene expression regulation at the wholegenome level. Multiple computational tools have been developed to predict miRNA:mRNA interactions. Nonetheless, many of these tools are developed in various small datasets, which each represent a limited sample space.
17p
visilicon2711
20-08-2021
11
1
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Osteoporosis is a common comorbidity in non-cystic fibrosis (non-CF) bronchiectasis patients. We determined whether desaturation during 6-min walk test (6MWT) can be a predictor for osteoporosis risk.
9p
vimontana2711
05-04-2021
4
1
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Multidetector computed tomography (MDCT) angiography is a useful examination to detect the source of the bleeding in patients with hemoptysis. The aim of the study was to prospectively evaluate the role and clinical efficacy of MDCT angiography before bronchial artery embolization (BAE) for the management of hemoptysis, and to investigate the predictors of early recurrence.
10p
vimichigan2711
26-03-2021
13
1
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The aim of a recent research project was the investigation of the mechanisms involved in the onset of type 2 diabetes in the absence of familiarity. This has led to the development of a computational model that recapitulates the aetiology of the disease and simulates the immunological and metabolic alterations linked to type-2 diabetes subjected to clinical, physiological, and behavioural features of prototypical human individuals.
19p
viwyoming2711
16-12-2020
7
1
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Computational methods for the prediction of protein features from sequence are a long-standing focus of bioinformatics. A key observation is that several protein features are closely inter-related, that is, they are conditioned on each other.
14p
vikentucky2711
26-11-2020
9
1
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Transient protein-protein interactions (PPIs), which underly most biological processes, are a prime target for therapeutic development. Immense progress has been made towards computational prediction of PPIs using methods such as protein docking and sequence analysis.
12p
vikentucky2711
26-11-2020
8
0
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As one of the most common post-transcriptional modifications (PTCM) in RNA, 5-cytosine-methylation plays important roles in many biological functions such as RNA metabolism and cell fate decision.
21p
vikentucky2711
24-11-2020
9
1
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The identification of immunogenic regions on the surface of antigens, which are able to be recognized by antibodies and to trigger an immune response, is a major challenge for the design of new and effective vaccines. The prediction of such regions through computational immunology techniques is a challenging goal, which will ultimately lead to a drastic limitation of the experimental tests required to validate their efficiency.
12p
vioklahoma2711
19-11-2020
13
2
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The β-Lactamase (BL) enzyme family is an important class of enzymes that plays a key role in bacterial resistance to antibiotics. As the newly identified number of BL enzymes is increasing daily, it is imperative to develop a computational tool to classify the newly identified BL enzymes into one of its classes.
12p
viconnecticut2711
29-10-2020
10
2
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Replanning in intensity-modulated radiotherapy (IMRT) has been reported to improve quality of life and loco-regional control in patients with nasopharyngeal cancer (NPC). Determination of the criteria for replanning is, however, urgently needed. We conducted a prospective study to determine when and for what type of patients is replanning preferred through weekly repeat computed tomography (CT) imaging during the course of IMRT.
9p
vijennie2711
29-09-2020
16
1
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Over the decades, personality factors (attitude, self-efficacy, anxiety and computer experience) have pervaded the underpinning determinants of behavioural intentions to accept and use emerging technologies, chiefly in purviews where integration is into the working processes that may be pro traditional. The chasm in the literature has been how these technology personality factors extensively relate within and among themselves in a definite model exclusive to these factors, and their overall variance explained in usage intentions.
26p
kequaidan1
05-11-2019
33
1
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Wittman (1941) developed a prognosis scale for predicting outcome of electroshock therapy in schizophrenia, which consisted of 30 variables rated from social history and psychiatric examination. The predictors ranged from semi-objective matters (such as duration of psychosis) to highly interpretive judgments (such as anal-erotic vs. oral-erotic character). None of the predictor variables was psychometric.
32p
loixinloi
08-05-2013
34
1
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