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Contact map
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We address the question of whether the Thom-Boardman symbol of a map germ is an invariant with respect to bi-Lipschitz right equivalence. We give a counterexample showing that in general the answer is negative. We prove that the rank of a map germ is a bi-Lipschitz contact invariant. Consequently, the first Thom-Boardman symbol and its length are bi-Lipschitz contact invariants.
8p
vimelindagates
18-07-2022
19
2
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Robustness and evolutionary stability of gene expression in the human genome are established by an array of redundant enhancers. Results: Using Hi-C data in multiple cell lines, we report a comprehensive map of promoters and active enhancers connected by chromatin contacts, spanning 9000 enhancer chains in 4 human cell lines associated with 2600 human genes.
14p
vielonmusk
30-01-2022
11
0
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HiC-Pro is an optimized and flexible pipeline for processing Hi-C data from raw reads to normalized contact maps. HiC-Pro maps reads, detects valid ligation products, performs quality controls and generates intra- and inter-chromosomal contact maps. It includes a fast implementation of the iterative correction method and is based on a memory-efficient data format for Hi-C contact maps.
11p
viaristotle
29-01-2022
13
0
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We present MUSTACHE, a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. MUSTACHE employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in contact maps.
17p
viarchimedes
26-01-2022
12
0
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Hi-C and capture Hi-C (CHi-C) are used to map physical contacts between chromatin regions in cell nuclei using high-throughput sequencing. Analysis typically proceeds considering the evidence for contacts between each possible pair of fragments independent from other pairs.
13p
vigiselle2711
30-08-2021
8
1
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The document "Lectures on Symplectic Geometry" has contents: ymplectic manifolds, Symplectomorphisms, local forms, contact manifolds, compatible almost complex structures, ̈Kahler manifolds, hamiltonian mechanics,...
225p
phannguyenhaminhths
18-08-2021
9
1
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Proximity ligation based techniques, like Hi-C, involve restriction digestion followed by ligation of formaldehyde cross-linked chromatin. Distinct chromatin states can impact the restriction digestion, and hence the visibility in the contact maps, of engaged loci.
15p
vijeeni2711
24-07-2021
6
0
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Hi-C is a molecular biology technique to understand the genome spatial structure. However, data obtained from Hi-C experiments is biased. Therefore, several methods have been developed to model Hi-C data and identify significant interactions.
10p
vijeeni2711
24-07-2021
8
0
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In diploid cells, it is important to construct maternal and paternal Hi-C contact maps respectively since the two homologous chromosomes can differ in chromatin three-dimensional (3D) organization.
13p
vijeeni2711
30-06-2021
8
1
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This present optimized optical system; more data on aberration measurement; micro lens array; customized lens manufacturing; high order aberration map is on; ultra high precision KER Data; contact lens fitting assistance guide... Huvitz Việt Nam (Hotline: 094 686 1123) là nhà phân phối chính thức Thiết bị ngành Kính Mắt và Nhãn khoa của Hãng Huvitz - Hàn Quốc tại Việt Nam. http://huvitzvn.com https://www.facebook.com/huvitzvn
2p
domanhhung6291@gmail.com
07-05-2021
33
0
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As genome sequencing is becoming routine in biomedical research, the total number of protein sequences is increasing exponentially, recently reaching over 108 million. However, only a tiny portion of these proteins (i.e. ~75,000 or < 0.07%) have solved tertiary structures determined by experimental techniques.
12p
viwyoming2711
16-12-2020
11
1
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The structures of biological macromolecules provide a framework for studying their biological functions. Three-dimensional structures of proteins, nucleic acids, or their complexes, are difficult to visualize in detail on flat surfaces, and algorithms for their spatial superposition and comparison are computationally costly.
11p
viwyoming2711
16-12-2020
18
1
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Hi-C and its variant techniques have been developed to capture the spatial organization of chromatin. Normalization of Hi-C contact map is essential for accurate modeling and interpretation of high-throughput chromatin conformation capture (3C) experiments.
25p
vikentucky2711
24-11-2020
13
2
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Despite the rapid progress of protein residue contact prediction, predicted residue contact maps frequently contain many errors. However, information of residue pairing in β strands could be extracted from a noisy contact map, due to the presence of characteristic contact patterns in β-β interactions.
19p
viconnecticut2711
28-10-2020
11
1
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The spatial configuration of chromosomes is essential to various cellular processes, notably gene regulation, while architecture related alterations, such as translocations and gene fusions, are often cancer drivers. Thus, eliciting chromatin conformation is important, yet challenging due to compaction, dynamics and scale.
15p
vicolorado2711
22-10-2020
11
0
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Genome-wide ligation-based assays such as Hi-C provide us with an unprecedented opportunity to investigate the spatial organization of the genome. Results of a typical Hi-C experiment are often summarized in a chromosomal contact map, a matrix whose elements reflect the co-location frequencies of genomic loci.
18p
vicolorado2711
22-10-2020
37
0
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In the present paper we obtain sharp estimates for the squared norm of the second fundamental form in terms of the mapping function for contact 3 -structure CR-warped products isometrically immersed in Sasakian space form.
8p
tuongvidanh
06-01-2019
20
2
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ASIA Investment marketview Q3 2010 presents market overview, economic update, features, retail, industrial, luxury residential, major micromarkets by sector, terminology & definitions, contacts, ASIA offices, Asia map.
64p
votinhdon91
11-09-2014
30
7
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The troponin (Tn) complex is formed by TnC, TnI and TnT and is respon-sible for the calcium-dependent inhibition of muscle contraction. TnC and TnI interact in an antiparallel fashion in which the N domain of TnC binds in a calcium-dependent manner to the C domain of TnI, releasing the inhibitory effect of the latter on the actomyosin interaction. While the crys-tal structure of the core cardiac muscle troponin complex has been deter-mined, very little high resolution information is available regarding the skeletal muscle TnI–TnC complex. ...
0p
awards
05-04-2013
30
1
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If the process for selling goods on World of Good by eBay seems daunting to you, be aware that the company has anticipated this and has developed a program to help Sellers and Producer Groups who don’t have the time, experience, Internet connection, or otherwise lack capacity to complete the process outlined above. This initiative is called the Marketplace Access Program (MAP) and puts sellers in contact with what World of Good by eBay calls MAP Agents. Map Agents are experienced eBay sellers who help qualified WorldofGood.
0p
dangsuynghi
15-03-2013
54
7
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