Control of gene expression

There are many evidences showing the fact that some hard conditions from environment, namely abiotic stress, could make several significantly negative impacts on crop production. However, some plant species can overcome these bad situations by complicated mechanisms. This study has shown the result of the construction the recombinant vector carrying CodA gene which could encode an enzyme, named choline oxidase, and is controlled by Rd29A promoter.

8p vilarry 01-04-2024 5 1   Download

We present an assay to experimentally test the regulatory effects of genetic variants within transcripts using CRISPR/ Cas9 followed by targeted sequencing. We applied the assay to 32 premature stop-gained variants across the genome and in two Mendelian disease genes, 33 putative causal variants of eQTLs, and 62 control variants in HEK293T cells, replicating a subset of variants in HeLa cells.

10p vibransone 28-03-2024 7 2   Download

Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes (T2D). However, the underlying biological mechanisms for many of these associations remain unknown. GWAS signals close to the glucokinase regulatory protein gene (GCKR) have been reported for lipid and glucose metabolism traits and the risk of T2D.

14p vioraclene 31-03-2024 3 2   Download

Expression quantitative trait loci (eQTL) databases represent a valuable resource to link diseaseassociated SNPs to specific candidate genes whose gene expression is significantly modulated by the SNP under investigation.

16p vioraclene 31-03-2024 4 2   Download

Part 1 book "Essential cell biology" includes content: Cells - The fundamental units of life, chemical components of cells energy, catalysis and biosynthesis, protein structure and function, DNA and chromosomes, DNA replication and repair, from DNA to protein - How cells read the genome, control of gene expression, how genes and genomes evolve, analyzing the structure and function of genes.

398p muasambanhan08 01-03-2024 2 1   Download

Ebook "Untranslated gene regions and other non-coding elements: Regulation of eukaryotic gene expression" pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.​

63p manmanthanhla0201 26-02-2024 5 1   Download

Part 1 book "Molecular cell biology" includes content: Life begins with cells, chemical foundations, protein structure and function, basic molecular genetic mechanisms, biomembranes and cell architecture, integrating cells into tissues, transport of ions and small molecules across cell membranes, cellular energetics, molecular genetic techniques and genomics, molecular structures of genes and chromosomes, transcriptional control of gene expression.

490p muasambanhan07 18-02-2024 2 2   Download

Ebook "Regulation of gene expression in plants: The role of transcript structure and processing" presents some of the most recent, novel and fascinating examples of transcriptional and posttranscriptional control of gene expression in plants and, where appropriate, provides comparison to notable examples of animal gene regulation.

216p tachieuhoa 28-01-2024 6 2   Download

Breast cancer (BC) is one of the malignant diseases threatening the life and health of women worldwide. The CYP4B1 gene was abnormally expressed in BC and was associated with the prognosis of BC patients. This study aimed to explore the relationship between CYP4B1 single nucleotide polymorphisms (SNPs) and BC risk in Chinese women.

14p vialfrednobel 23-12-2023 6 3   Download

Part 1 book "Alberts - Essential cell biology" includes content: Cells - the fundamental units of life; chemical components of cells; energy, catalysis, and biosynthesis; protein structure and function; DNA and chromosomes; DNA replication, repair, and recombination; from DNA to protein - how cells read the genome; control of gene expression; how genes and genomes evolve; modern recombinant DNA technology.

383p muasambanhan01 13-12-2023 4 2   Download

Part 2 book "Control of pig reproduction VIII" includes content: Sperm survival following colloid centrifugation varies according to the part of the sperm-rich fraction used, the role of gene discovery, QTL analyses and gene expression in reproductive traits in the pig, nutritional and lactational effects on follicular development in the pig, intra-follicular regulatory mechanisms in the porcine ovary ,... and other contents.

172p oursky10 04-12-2023 3 2   Download

Endocrine-resistant breast cancers have elevated expression of XBP1, where it drives endocrine resistance by controlling the expression of its target genes. Despite the in-depth understanding of the biological functions of XBP1 in ER-positive breast cancer, efectors of endocrine resistance downstream of XBP1 are poorly understood. The aim of this study was to identify the XBP1-regulated genes contributing to endocrine resistance in breast cancer.

16p vischultz 20-10-2023 1 1   Download

Part 3 book "Biochemistry" includes content: The biosynthesis of amino acids, nucleotide biosynthesis, the biosynthesis of membrane lipids and steroids, the integration of metabolism, DNA replication, repair, and recombination, RNA synthesis and processing, protein synthesis, the control of gene expression in prokaryotes, the control of gene expression in eukaryotes.

336p oursky07 24-10-2023 9 3   Download

Part 1 book "Molecular cell biology" includes content: Molecules, cells, and model organisms; chemical foundations; protein structure and function; culturing and visualizing cells 1fundamental molecular genetic mechanisms; molecular genetic techniques, biomembrane structure; genes, genomics, and chromosomes; transcriptional control of gene expression; post transcriptional gene control.

514p oursky06 17-10-2023 4 1   Download

Part 2 book "Molecular cell biology" includes content: Transmembrane transport of ions and small molecules; cellular energetics; moving proteins into membranes and organelles; vesicular traffic, secretion, and endocytosis; signal transduction and protein–coupled receptors; signaling pathways that control gene expression; cell organization and movement i: microfilaments; cell organization and movement II- microtubules and intermediate filaments; the eukaryotic cell cycle... and other contents.

448p oursky06 17-10-2023 3 1   Download

Part 1 book "Animal cell technology, from biopharmaceuticals to gene therapy" includes content: Introduction to animal cell technology, animal cells - basic concepts, cloning and expression of heterologous proteins in animal cells, cell metabolism and its control in culture, culture media for animal cells, post-translational modification of recombinant proteins, mechanisms of cell proliferation and cell death in animal cell culture in vitro, mathematical models for growth and product synthesis in animal cell culture.

259p oursky05 20-09-2023 7 3   Download

Part 1 book "Molecular biology of the cell" includes content: Cells and genomes; cell chemistry and bioenergetics; proteins DNA, chromosomes, and genomes; DNA, replication, repair, and recombination; how cells read the genome - from DNA to protein; control of gene expression; analyzing cells, molecules, and systems; visualizing cells.

599p oursky02 06-08-2023 6 3   Download

Currently, searching for new protease inhibitors is of interest to many scientists around the world because they play an important role in controlling harmful proteases. As terrestrial bioactive resources are becoming increasingly depleted, studies are aimed at finding other sources, for example, the ocean.

10p vicaptainmarvel 21-04-2023 4 2   Download

Post-transcriptional regulation is the control of gene expression at the RNA level. After produced, the stability and distribution of the different transcripts are regulated by means of RNA-binding proteins (RBPs).

8p vicaptainmarvel 21-04-2023 11 2   Download

Researchers have been exploring the molecular mechanisms underlying the control of periodontal ligament stem cell (PDLSC) osteogenic differentiation. Recently, long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) were shown to function as competitive endogenous RNAs (ceRNAs) to regulate the effect of microRNAs (miRNAs) on their target genes during cell differentiation.

13p vinarcissa 21-03-2023 2 1   Download