Correlated response

One-third of diffuse large B-cell lymphoma (DLBCL) patients suffer relapse after standard treatment. Eukaryotic initiation factor 3a (eIF3a) is a key player in the initial stage of translation, which has been widely reported to be correlated with tumorigenesis and therapeutic response. This study aimed to explore the biological role of eIF3a, evaluate its prognostic and therapeutic potential in DLBCL.

16p vishanshan 27-06-2024 2 1   Download

Pyroptosis is a type of programmed cell death mediated by the gasdermin family. Gasdermin B (GSDMB), as a member of gasdermin family, can promote the occurrence of cell pyroptosis. However, the correlations of the GSDMB expression in colorectal cancer with clinicopathological predictors, immune microenvironment, and prognosis are unclear.

13p vishanshan 27-06-2024 1 1   Download

In the context of breast cancer (BC), the correlation between lymphocytes and clinical outcomes, along with treatment response, has garnered attention. Despite this, few investigations have delved into the interplay among distinct peripheral blood lymphocyte (PBL) types, immune attributes, and their clinical implications within the BC landscape.

10p vikoch 27-06-2024 3 1   Download

The purpose of this paper is to examine the correlations of IFRS implementation and corporate social responsibility on Earnings quality of Indonesia and Malaysia Oil Plantations companies, during the full convergences of IFRS period (2012- 2016). The logistics industry is becoming increasingly competitive, and supply chains becoming increasingly complex. This research is using data from the annual financial report issued by the company that is registered at the Indonesian stock exchange and Malaysia stock exchange, from 2012 to 2016.

11p longtimenosee09 08-04-2024 6 1   Download

Ebook Physical logical security convergence: Powered by enterprise security management - Part 2 includes contents: Chapter 8 the new security model: the trusted enterprise; chapter 9 ESM architecture; chapter 10 log collection; chapter 11 real-time event correlation, analysis, and response; chapter 12 event storage and forensic analysis; chapter 13 bridging the chinese wall; chapter 14 physical and logical access; chapter 15 intelligent video analytics; chapter 16 environmental sensors; chapter 17 protecting critical infrastructure: process control and SCADA; chapter 18 final thoughts.

342p longtimenosee05 31-03-2024 0 0   Download

Angiosarcoma is an aggressive tumor. Recent case series describe exceptional responses to checkpoint blockade in this disease. Methods: Herein, we explored the genomic correlates of 48 angiosarcomas from the Angiosarcoma Project (12,499 variants analyzed in 6603 genes; whole-exome sequencing) versus 10,106 pan-cancer tumors in The Cancer Genome Atlas including 235 sarcomas but no angiosarcoma.

6p vibransone 28-03-2024 4 2   Download

The T cell-inflamed tumor microenvironment, characterized by CD8 T cells and type I/II interferon transcripts, is an important cancer immunotherapy biomarker. Tumor mutational burden (TMB) may also dictate response, and some oncogenes (i.e., WNT/β-catenin) are known to mediate immunosuppression.

19p vibransone 28-03-2024 3 2   Download

The research examines a model that describes the correlation between sustainability awareness, green supply chain management (GSCM) practices (green purchasing, consumer engagement and investment recovery) and firms’ performance (FP). Survey responses from 210 manufacturing firms influential in Indonesia, this research has developed many significant observations.

9p longtimenosee06 27-03-2024 2 2   Download

Currently, over half of breast cancer cases are unrelated to known risk factors, highlighting the importance of discovering other cancer-promoting factors. Since crosstalk between gut microbes and host immunity contributes to many diseases, we hypothesized that similar interactions could occur between the recently described breast microbiome and local immune responses to influence breast cancer pathogenesis.

17p vibransone 28-03-2024 3 1   Download

The study found that Vietnamese tourists mainly visit Korea because destination image, cultural similarity, culinary background, and Hallyu. Path analysis reveals that responsiveness and price do not correlate with customer satisfaction.

16p vibego 02-02-2024 1 0   Download

Ebook "Autophagy: Molecular biology intelligence unit" provide tremendous insight into autophagy, particularly at the mechanistic level. Autophagy is a process in which a cell carries out “self eating” either in response to starvation or various hormonal cues. This process occurs in all eukaryotic cells. It plays a normal role in cellular physiology but has received tremendous attention in the last few years because it has been shown to correlate with various diseases in humans.

325p tachieuhoa 28-01-2024 4 2   Download

To quantify the dose-response relationship of changes in pelvic bone marrow (PBM) functional MR radiomic features (RF) during concurrent chemoradiotherapy (CCRT) for patients with cervical cancer and establish the correlation with hematologic toxicity to provide a basis for PBM sparing.

12p vileonardodavinci 23-12-2023 4 2   Download

Lenvatinib is appropriate for reducing the production of nitric oxide (NO) and facilitating as block angiogenesis. However, to our knowledge, there are no data that support the correlation between NO and clinical response in patients who received lenvatinib therapy for HCC.

10p vialfrednobel 23-12-2023 7 3   Download

Difference in clinical responses to cancer therapy in each patient is from several factors. Gastrointestinal microbiota is one of the reasons. However, this correlation remains unknown. This study aims to explore correlation between gastrointestinal microbiota profile and clinical outcomes in Thai advanced non-small cell lung cancer (NSCLC) according to epidermal growth factor receptor (EGFR) status.

15p vialfrednobel 23-12-2023 5 3   Download

Composition of the intestinal microbiota has been correlated to therapeutic efficacy of immune check‑point inhibitors (ICI) in various cancer entities including melanoma. Prediction of the outcome of such therapy, how‑ever, is still unavailable.

11p vialfrednobel 23-12-2023 2 2   Download

Measuring scales are an indispensable tool in rehabilitation interventions, especially when you want to intervene with Traditional medicine methods on post-stroke patients. Appropriate scales are a prerequisite to assessing treatment response, the degree of recovery, and the value of the intervention method.

10p vikissinger 21-12-2023 5 2   Download

Immune checkpoint inhibitor (ICI) therapy has become a viable treatment strategy in bladder cancer. However, treatment responses vary, and improved biomarkers are needed. Crucially, the characteristics of immune cells remain understudied especially in squamous diferentiated bladder cancer (sq-BLCA). Here, we quantitatively analysed the tumour-immune phenotypes of sq-BLCA and correlated them with PD-L1 expression and FGFR3 mutation status.

15p vischultz 20-10-2023 5 1   Download

To assess construct validity and responsiveness of the Expanded Prostate Cancer Index Composite Instrument (EPIC-26) relative to the Short-Form Six-Dimension (SF-6D) and Assessment of Quality of Life 6-Dimension (AQoL-6D) in patients following treatment for prostate cancer.

13p vischultz 20-10-2023 2 1   Download

Thermal therapy induces an immune response in patients with hepatocellular carcinoma (HCC), but the dynamic characteristics of the natural killer (NK) cell immune response post-thermal ablation remain unclear.

14p vischultz 20-10-2023 1 1   Download

The scavenger receptor CD36 was reported to be highly expressed on tumor-infiltrating CD8+ T cells, but the clinical role remains obscure. This study aims to explore the infiltration and clinical value of CD36+CD8+ T cells in NSCLC.

13p vischultz 20-10-2023 2 1   Download