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Corresponding alkyl halides
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The therapeutic applications of 1,2,4-triazoles motivated us to synthesize some new derivatives. Two series of S -substituted derivatives (8a–8j, 12a–12i) of 5-{1-[(4-chlorophenyl)sulfonyl]-3-piperidinyl}-4-phenyl-4H -1,2,4-triazol3-thiol (6) have been synthesized and evaluated for their biological potential.
20p
tudichquannguyet
29-11-2021
9
1
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A novel one-pot, solvent-free method for the synthesis of dithiocarbamates was developed through the reaction of corresponding alkyl halides, amines and carbon disulfide employing catalytic amount of benzyl trimethyl ammonium hydroxide (Triton-B).
8p
tocectocec
25-05-2020
10
1
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Phase-transfer-catalyzed alkylation of glycinate Schiff base with racemic secondary alkyl halides proceeded with excellent levels of synand enantioselectivities under the influence of a chiral quaternary ammonium bromide and 18- crown-6. The alkylation product can be selectively converted to the corresponding anti isomer, allowing the preparation of all the stereoisomers of β-alkyl-α-amino acid derivatives.
12p
heoxinhkute
19-07-2010
81
5
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