Coumarin antibiotic

Novobiocin is a coumarin antibiotic, which affects also eukaryotic cells inhibiting activity of Heat shock protein 90 (Hsp90). The Hsp90 represents a molecular chaperone critical for stabilization and activation of many proteins, particularly oncoproteins that drive cancer progression.

6p vienzym2711 03-04-2020 8 2   Download

Coumarin and its derivatives are heterocyclic compounds which gives toxic effects when it is used in higher quantity. In lower amount it is also toxic to marine plants and animals like fish, phytoplanktons, zooplanktons etc. According to various data it is confirmed that coumarin can be harmful for human being also though it is used in cosmetics, pharmaceutical industries and various medicines like anti-cancer and anti-coagulant.

5p quenchua2 15-12-2019 7 0   Download