Cyclophilin B

The molecular pathogenesis of endometrial cancer is not completely understood. CypB upregulated in many cancers, however, its role in endometrial carcinoma has not been studied. Here, we determine the effect of CypB on the growth of endometrial cancer.

8p vimahuateng 26-11-2021 10 1   Download

Cyclophilins facilitate the peptidyl-prolyl isomerization of atrans-isomer to a cis-isomer in the refolding process of unfolded proteins to recover the natural folding state with cis-proline conformation.Todate, only short peptideswitha cis-formproline have been observed in complexes of human and Escherichia coliproteins of cyclophilin A, which is present in cytoplasm. The crystal structures analyzed in this study show two complexes inwhich peptides having atrans-form proline, i.e.

10p awards 05-04-2013 26 2   Download

Variations in the number of SMEs reflect changes in the structure as well as the ownership of business and industry in general. Much of the increase in SME registrations in the EU in the 1990s reflected the downsizing and restructuring of large companies. Previously ‘internalised’ services and processes were moved out of companies focusing on their ‘core’ business. Similarly, in transition economies, privatisation and restructuring have led to the creation of new small firms.

37p bi_ve_sau 05-02-2013 50 2   Download