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Cytotoxic enterotoxin
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This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors and cellular transport processes of Clostridium botulinum neurotoxins, Clostridium botulinum C3 toxin, Clostridium difficile toxins, binary clostridial enterotoxins, anthrax toxins and diphtheria toxin.
261p
vimeyers
29-05-2024
5
1
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Bacterial toxins have evolved to an effective therapeutic option for cancer therapy. The Clostridium perfringens enterotoxin (CPE) is a pore-forming toxin with selective cytotoxicity. The transmembrane tight junction proteins claudin-3 and -4 are known high affinity CPE receptors. Their expression is highly upregulated in human cancers, including breast, ovarian and colon carcinoma.
14p
vimale2711
21-08-2020
14
2
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The Genus Aeromonas belongs to facultative, anaerobic gram negative bacteria. Several mesophilic species of Aeromonas cause septicaemia in a variety of aquatic organisms and gastrointestinal diseases in humans. The virulence of Aeromonas is considered multifactorial and are known to possess aerolysins, hemolysins, proteases, phospholipases, lipases, adhesions and enterotoxins. Therefore, the importance of present work lies in detecting the virulence genes in Aeromonas sobria isolated from diseased fish, rohu.
7p
nguaconbaynhay3
07-02-2020
14
1
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