Data reuse

Despite growing numbers of immune checkpoint blockade (ICB) trials with available omics data, it remains challenging to evaluate the robustness of ICB response and immune evasion mechanisms comprehensively. To address these challenges, we integrated large-scale omics data and biomarkers on published ICB trials, nonimmunotherapy tumor profiles.

8p vibransone 28-03-2024 7 2   Download

In this chapter, the following content will be discussed: Component-based approach: reuse, integration, reuse of components not originally designed as reusable components, reuse of application patterns; level of integration can be chosen basic integration reusing the applications “as is”, data level (using relational database connector), implementation in COM.

28p haojiubujain04 27-07-2023 10 4   Download

Ebook PHP and MySQL web development: Part 1 includes contents: Chapter 1 PHP crash course, Chapter 2 Storing and retrieving data, Chapter 3 Using arrays, Chapter 4 String manipulation and regular expressions, Chapter 5 Reusing code and writing functions, Chapter 6 Object-Oriented PHP, Chapter 7 Designing your web database, Chapter 8 Creating your web database, Chapter 9 Working with your MySQL database, Chapter 10 Accessing your MySQL database from the web with PHP, Chapter 11 Advanced MySQL, Chapter 12 Running an e-commerce site, Chapter 13 E-commerce security issues, Chapter 14 Implementi...

374p haojiubujain03 24-07-2023 9 6   Download

Although omics datasets represent valuable assets for hypothesis generation, model testing, and data validation, the infrastructure supporting their reuse lacks organization and consistency. Using nuclear receptor signaling transcriptomic datasets as proof of principle, we developed a model to improve the discoverability, accessibility, and citability of published omics datasets.

6p visteverogers 24-06-2023 3 2   Download

Automated clinical phenotyping is challenging because word-based features quickly turn it into a high-dimensional problem, in which the small, privacy-restricted, training datasets might lead to overfitting. Pretrained embeddings might solve this issue by reusing input representation schemes trained on a larger dataset.

8p visteverogers 24-06-2023 6 2   Download

In 2013, we released Project Tycho, an open-access database comprising 3.6 million counts of infectious disease cases and deaths reported for over a century by public health surveillance in the United States. Our objective is to describe how Project Tycho version 1 (v1) data has been used to create new knowledge and technology and to present improvements made in the newly released version 2.0 (v2).

10p visteverogers 24-06-2023 4 2   Download

Finding relevant datasets is important for promoting data reuse in the biomedical domain, but it is challenging given the volume and complexity of biomedical data. Here we describe the development of an open source biomedical data discovery system called DataMed, with the goal of promoting the building of additional data indexes in the biomedical domain.

9p visteverogers 24-06-2023 3 2   Download

Collider bias is a common threat to internal validity in clinical research but is rarely mentioned in informatics education or literature. Conditioning on a collider, which is a variable that is the shared causal descendant of an exposure and outcome, may result in spurious associations between the exposure and outcome.

7p vighostrider 25-05-2023 6 2   Download

The development of phenotypes using electronic health records is a resource-intensive process. Therefore, the cataloging of phenotype algorithm metadata for reuse is critical to accelerate clinical research.

7p vighostrider 25-05-2023 3 2   Download

Lecture Object-Oriented programming - Lesson 41: Standard template library. The main topics covered in this chapter include: C++ programmers commonly use many data structures and algorithms; so C++ standard committee added the STL to C++ standard library; STL is designed to operate efficiently across many different applications;...

38p linyanjun_2408 23-04-2022 14 1   Download

Single-cell RNA-seq datasets are often first analyzed independently without harnessing model fits from previous studies, and are then contextualized with public data sets, requiring time-consuming data wrangling. We address these issues with sfaira, a single-cell data zoo for public data sets paired with a model zoo for executable pre-trained models.

21p viarchimedes 26-01-2022 6 0   Download

Templates are an important part of C++ that allows a programmer to reuse existing code for new purposes. In some sense, templates ensure that you don’t have to continually “reinvent the wheel.” This lecture introduces how to implement and use template functions. The best time for the lecture is just before the students read chapter 6.

13p tradaviahe19 29-03-2021 28 2   Download

Scientists rarely reuse expert knowledge of phylogeny, in spite of years of effort to assemble a great “Tree of Life” (ToL). A notable exception involves the use of Phylomatic, which provides tools to generate custom phylogenies from a large, pre-computed, expert phylogeny of plant taxa.

17p viwyoming2711 16-12-2020 15 1   Download

In this chapter, the following content will be discussed: This chapter augments your database application development skills with stored procedures and triggers. Stored procedures provide reuse of common code, while triggers provide rule processing for common tasks.

29p larachdumlanat122 26-11-2020 12 1   Download

Genome-wide gene expression profiling of mammalian cells is becoming a staple of many published biomedical and biological research studies. Such data is deposited into data repositories such as the Gene Expression Omnibus (GEO) for potential reuse.

12p vioklahoma2711 19-11-2020 11 1   Download

This chapter augments your database application development skills with stored procedures and triggers. Stored procedures provide reuse of common code, while triggers provide rule processing for common tasks. Together, stored procedures and triggers support customization of database applications and improved productivity in developing database applications.

101p nanhankhuoctai9 23-06-2020 11 0   Download

The following will be discussed in this chapter: Principles of cellular networks, cellular geometries, frequency reuse, increasing capacity, macrocell and microcell, operation of cellular system, call stages, design factors, impairments, ist generation cellular networks, 2nd generation cellular networks.

73p nanhankhuoctai8 23-06-2020 20 3   Download

Quantification of mass flows in production lines and waste treatment lines, as well as quantification of energy consumption at a factory is always challenges in cleaner production and pollution control decision making. The case study has conducted at a representative steel making complex in Vietnam, simulating the material flows of water and waste streams, and energy balance (EB) for water production and wastewater treatment processes, by using STAN (subSTance flow ANalysis) and SANKEY software, respectively.

13p angicungduoc5 13-06-2020 39 0   Download

Lecture 28 - Software reuse. In this chapter, the following content will be discussed: Code restructuring, data restructuring; forward engineering; client-server architectures, object-oriented architectures; economics of reengineering; cost benefit analysis; software reuse; benefits of reuse.

20p nanhankhuoctai3 25-05-2020 13 0   Download

The current water shortage in Egypt is 13.5 Billion cubic meter per year (BCM/yr) and is expected to continuously increase. Currently, this water shortage is compensated by drainage reuse which consequently deteriorates the water quality. Therefore, this research was commenced with the objective of assessing different scenarios for 2025 using the Water Evaluation and Planning (WEAP) model and by implementing different water sufficiency measures. Field data were assembled and analyzed, and different planning alternatives were proposed and tested in order to design three future scenarios.

10p kequaidan1 16-11-2019 30 1   Download