DDR system

Genome stability is maintained by the DNA damage repair (DDR) system composed of multiple DNA repair pathways of hundreds of genes. Germline pathogenic variation (PV) in DDR genes damages function of the affected DDR genes, leading to genome instability and high risk of diseases, in particular, cancer.

17p vishanshan 27-06-2024 2 1   Download

DNA damage repair (DDR) system is vital in maintaining genome stability and survival. DDR consists of over 160 genes in 7 different pathways to repair specific type of DNA damage caused by external and internal damaging factors. The functional importance of DDR system implies that evolution could play important roles in maintaining its functional intactness to perform its function.

10p vitzuyu2711 29-09-2021 5 1   Download

Results showed that hourly variations of flow rate corresponded to the water consumption trend. Average discharge flow rate was equivalent to 38.5 ± 4.4 L/cap/day, which was much lower than that on DdRs (64.2 ± 25.0 L/cap/day). In contrast, pollutant concentrations on DdDs were higher than those on DdRs and fluctuated slightly in a day and among days in a week

8p cumeo3000 01-08-2018 17 0   Download

Upon completing this lesson, you will be able to: Configure legacy DDR, given a functioning remote access router and a physical ISDN connection Use show commands to identify the anomalies in the legacy DDR configurations, given a functioning remote access router and a physical ISDN connection Use debug commands to identify the anomalies in the legacy DDR configurations, given a functioning remote access router and a physical ISDN connection

28p trinhvang 25-01-2013 56 3   Download

Upon completing this module, you will be able to: Configure ISDN BRI, ISDN PRI, and legacy DDR, given a functioning remote access router and a physical ISDN connection Use show commands to identify the anomalies in the ISDN BRI, ISDN PRI, and legacy DDR configurations, given a functioning remote access router and a physical ISDN connection Use debug commands to identify the anomalies in the ISDN BRI, ISDN PRI, and legacy DDR configurations, given a functioning remote access router and a physical ISDN connection...

22p trinhvang 25-01-2013 39 4   Download