Decreased survival
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Neoadjuvant chemoradiotherapy (nCRT) and surgery have been recommended as the standard treatments for locally advanced esophageal squamous cell carcinoma (ESCC). In addition, nodal metastases decreased in frequency and changed in distribution after neoadjuvant therapy. This study aimed to examine the optimal strategy for lymph node dissection (LND) in patients with ESCC who underwent nCRT.
10p vikoch 27-06-2024 2 1 Download
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To assess prognostic value of pre-operative ipsilateral split renal function (SRF) on disease-free survival (DFS) and its association with aggressive pathological features in renal cell carcinoma (RCC) patients.
7p vileonardodavinci 23-12-2023 3 3 Download
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Preoperative sarcopenia is a predictor of poor survival in cancer patients. We hypothesized that sarcopenia could progress as occult metastasis arose, especially after highly invasive surgery for highly aggressive malignancy. This study aimed to evaluate the associations of postoperative changes in skeletal muscle mass volume with survival outcomes in patients who underwent surgery for perihilar cholangiocarcinoma.
10p vileonardodavinci 23-12-2023 3 2 Download
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Lung cancer is the third most frequent tumor and the main cause of death by tumor in Spain. Although the incidence and mortality are still significantly higher in men than in women, the disparity between the sexes is decreasing.
12p vileonardodavinci 23-12-2023 4 3 Download
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Efforts have been made to investigate the role of salvage radiotherapy (RT) in treating recurrent ovarian cancer (ROC). Stereotactic ablative radiation therapy (SABR) is a state-of-the-art therapy that uses intensity modulation to increase the fractional dose, decrease the number of fractions, and target tumors with high precision.
7p vialfrednobel 23-12-2023 5 4 Download
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Delay in the diagnosis of childhood cancer is one of the major health problem that contribute to decreased survival rates of children particularly in developing nations. Despite advances in the field of pediatric oncology, cancer remains a leading cause of death in children.
7p visharma 20-10-2023 5 2 Download
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Although the incidence of late-onset colorectal cancer (LOCRC) has decreased, the incidence of earlyonset colorectal cancer (EOCRC) is still rising dramatically. Heterogeneity in the genomic, biological, and clinicopathological characteristics between EOCRC and LOCRC has been revealed.
19p vioracle 29-09-2023 3 2 Download
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The age-stage, two-sex life table method was used for data analysis. The results indicated that EPF treatments affected the population growth rate of the aphids by causing prolongation of the development time, decrease in survival rate, shortening of adult longevity, and decrease in reproduction. The intrinsic rate of increase (r) and the finite rate of increase (λ) reflecting combined effects of all life history parameters were the highest in the control group and the lowest in M.
12p lyhuyenthu 31-01-2023 5 2 Download
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We aim to investigate the prognostic value of weight loss during radiotherapy (RT) among patients with nasopharyngeal carcinoma (NPC). High RT-PWL7 was significantly associated with decreased DFS, OS, and DMFS for NPC patients.
10p vikolindagrabar 27-07-2022 2 1 Download
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For patients with locally advanced (T3-4/N+) rectal cancer (LARC), the standard treatment is neoadjuvant chemoradiotherapy combined with total mesorectal resection, which greatly decreases local recurrence but does not improve overall survival.
8p viangelamerkel 27-07-2022 6 1 Download
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Previous studies have demonstrated that ICU (intensive care unit) survivors have decreased long-term survival rates compared to the general population. However, knowledge about how to identify ICU survivors with higher risk of death and the adjustable factors associated with mortality is still lacking.
9p viisaacnewton 25-04-2022 11 2 Download
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The red panda has been classifed as an endangered species due to the decreased number in the world and disease is considered as a great threat to the health and survival of the cubs in captivity.
6p vidarwin 22-02-2022 12 1 Download
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Acute liver injury in patients with ARDS decreases survival but early stages may be easily missed due to the lack of sufficient biomarkers signalling its onset. Accordingly, we tested in ARDS patients the hypotheses that microRNA-122, the foremost liver-related microRNA (miR), 1) is an sensitive and specific early predictor for potential liver injury and 2) analysed its impact on 30-day-survival.
12p vampires36 30-12-2021 10 0 Download
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Results revealed that non-sterile formulations exerted high numbers of total fungi and bacteria along the storage period; however, Az. chroococcum (A101) numbers were decreased over incubation time.
8p schindler 30-12-2021 11 0 Download
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This study was conducted to investigate the influence of tree thinning on habitat variables and small rodents in a natural deciduous forest in South Korea. We focused on the populations of the small forest-dwelling rodents, striped field mouse Apodemus agrarius and Korean field mouse A. peninsulae. Populations were monitored for 2 years in a natural deciduous forest subject to tree thinning. The coverage of ground vegetation and number and volume of downed trees were significantly increased after thinning.
7p dolomite36 30-12-2021 10 0 Download
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The mortality rate of patients with unresectable gastric cancer (UGC) has decreased with the development of chemotherapies and surgical techniques. However, the survival rate remains low. We retrospectively examined the prognostic significance of the pretreatment skeletal muscle mass index (SMI) and nutritional and inflammatory factors in patients with UGC.
11p vimahuateng 26-11-2021 9 2 Download
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Remyelination occurred at the fourth week of following withdrawal of cuprizone from diet. The level of mature and activated T cells, regulatory T cells, T helper cells and mature B cells increased during demyelination and decreased when cuprizone removed from diet. Further, both type 1 and type 2 cytokines together with the proinflammatory cytokines increased. The level of oligodendrocyte maturation and survival genes showed differential gene expression in parallel to that of demyelination and remyelination.
13p thiencuuchu 27-11-2021 9 1 Download
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The management of unresectable locally advanced colon cancer (LACC) remains controversial, as resection is not feasible. The goal of this study was to evaluate the treatment outcomes and toxicity of neoadjuvant chemoradiotherapy (NACRT) followed with surgery and adjuvant chemotherapy in patients with unresectable radically LACC.
13p vianrose2711 27-04-2021 9 1 Download
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LncRNA WT1-AS inhibits gastric cancer, while its role in other cancers is unknown. We investigated the role of WT1-AS in non-small cell lung cancer (NSCLC). Therefore, overexpression of WT1-AS may inhibit the cell proliferation and EMT to decrease cell migration and invasion of NSCLC cells by downregulating UCA1.
9p vianrose2711 27-04-2021 8 2 Download
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During the past decades, numerous efforts have been made to decrease the death rate among lung cancer patients. Nonetheless, the improvement in long-term survival has been limited and lung cancer is still a devastating disease.
4p vianthony2711 16-04-2021 12 1 Download