![](images/graphics/blank.gif)
Determining androgenic
-
Increasing interest has been devoted to the expression and possible role of sex hormone receptors in gastric cancer, but most of these findings are controversial. In the present study, the expression profile of sex hormone receptors in gastric cancer and their clinicopathological and prognostic value were determined in a large Chinese cohort.
10p
vijisoo2711
30-09-2020
14
0
Download
-
AZD3514 inhibits and down regulates the androgen receptor (AR) and has undergone clinical trials in prostate cancer. To provide proof-of-mechanism (POM) in patients, an immunohistochemistry (IHC) method for determination of AR in circulating tumour cells (CTC) was developed and validated.
8p
virose2711
25-09-2020
8
2
Download
-
Gross cystic disease fluid protein 15 (GCDFP-15), which is regulated by the androgen receptor (AR), is a diagnostic marker for mammary differentiation in histopathology. We determined the expression of GCDFP-15 in breast cancer subtypes, its potential prognostic and predictive value, as well as its relationship to AR expression.
10p
vilisa271
22-09-2020
7
1
Download
-
To determine whether the effect of androgen deprivation therapy (ADT) on the risk of biochemical failure varies at different doses of radiation in patients treated with definitive external beam radiation for intermediate risk prostate cancer (IRPC).
8p
vialabama2711
21-09-2020
8
0
Download
-
5α-reductase inhibitors (5-ARIs) inhibit the pathway of converting the testosterone to dihydrotestosterone and are widely used in benign prostatic hyperplasia patients. Since androgen receptor activation may play a role in urothelial tumorigenesis, we conducted this retrospective cohort study to determine whether 5α-reductase inhibitors (5-ARIs) administration is associated with bladder cancer mortality, bladder cancer recurrence and upper tract urothelial carcinoma mortality, using the Taiwan National Health Insurance database.
7p
viamsterdam
18-09-2020
15
1
Download
-
Recruitment of cofactors in the interaction of the androgen receptor (AR) and AR ligands plays a critical role in determining androgenic/antiandrogenic effects of the AR ligand on signaling, but the functions of key cofactors, including nuclear receptor coactivator (NCOA), remain poorly understood in prostate cancer cells treated with AR ligands.
8p
vinaypyidaw2711
26-08-2020
12
2
Download
-
Anti-Androgen Receptor (AR) therapy holds promise for a subset of AR expressing triple-negative breast cancer (TNBC) patients. However, current AR assays are suboptimal in detecting the dynamic range of AR expression, contributing to its controversial role in TNBC disease prognosis.
11p
vimale2711
21-08-2020
11
1
Download
-
Determine acute and subchronic toxicity of TD0014 in experimental animals; evaluate androgenic activity and effects on erectile function of TD0014 in experimental animals; evaluate the effects of TD0014 on sodium valproate-induced reproductive decline in male rats.
27p
tamynhan0
15-06-2020
4
1
Download
-
The prognostic relevance of circulating tumour cells (CTCs) in metastatic breast cancer (MBC) patients has been confirmed by several clinical trials. However, predictive blood-based biomarkers for stratification of patients for targeted therapy are still lacking.
9p
vikuala271
13-06-2020
10
1
Download
-
Flutamide is a potential antineoplastic drug classified as an anti-androgen. It is a therapy for men with advanced prostate cancer, administered orally after which it undergoes extensively first pass metabolism in the liver with the production of several metabolites.
15p
vijiraiya2711
27-05-2020
16
1
Download
-
An anther culture method was used for the production of doubled haploids (DHs) in Lithuanian barley and potato cultivars that were directly regenerated from embryoids (Caredda’s method) were applied to determine androgenic potential according to the green regenerant yield and other morphogenetic factors.
6p
vitamix
15-02-2019
14
0
Download
-
The aim of this study was to determine the androgenic capacity of some eggplant (Solanum melongena L.) varieties and breeding lines, and to establish the effectiveness of androgenesis induction in the less responsive genotypes by crossing with more responsive genotypes that have a high ability for haploid embryo formation.
7p
sony2711
01-02-2019
44
2
Download
-
Obesity is associated with a high prevalence of erectile dysfunction; how-ever, the pathophysiological link between obesity and erectile dysfunction remains poorly understood. In this minireview, we have attempted to eval-uate the existing literature pertaining to obesity and erectile dysfunction to determine whether a common pathophysiological link exists.
13p
viettel02
20-02-2013
31
2
Download
-
For men with metastatic prostate cancer who are willing to accept the adverse impact on over- all survival and gynaecomastia in the hope of retaining sexual function, anti-androgen mono- therapy with bicalutamide (150 mg) 14 is appropriate. Healthcare professionals should begin androgen withdrawal and stop bicalutamide treatment in men with metastatic prostate cancer who are taking bicalutamide monotherapy and who do not maintain satisfactory sexual function.
41p
khongmuonnghe
07-01-2013
39
3
Download
-
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: "Expanded risk groups help determine which prostate radiotherapy sub-group may benefit from adjuvant androgen deprivation therapy...
8p
toshiba10
15-10-2011
37
2
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)