Diagnosis and differential diagnosis

Pulmonary sclerosing (Pneumocytoma) is a rare benign pulmonary tumor of primitive epithelial origin. Because of the unspecific radiological features mimicking malignancies and their histological heterogeneity, the differential diagnosis with adenocarcinoma and carcinoid tumors is still challenging.

6p viling 11-10-2024 2 0   Download

The differential diagnosis between primary mesenteric lymphoma and others peritoneum diseases such as peritoneal carcinomatosis, malignant primary peritoneal mesotheliomas, tuberculous peritonitis, sarcomatosis, diffuse peritoneal leiomyomatosis or benign splenosis, constitutes a major problem in imaging techniques.

5p viling 11-10-2024 2 0   Download

The WHO Classification of Soft Tissue and Bone Tumours currently recognizes four categories of undifferentiated small round cell sarcoma: Ewing sarcoma, round cell sarcoma with EWSR1-non-ETS fusions including NFATc2 and PATZ1, CIC-rearranged sarcoma, and sarcoma with BCOR genetic alterations. These neoplasms frequently pose significant diagnostic challenges due to rarity and overlapping morphologic and immunohistochemical findings.

13p maitrangytb_94 24-07-2024 9 2   Download

Molecular knowledge regarding the primary esophageal achalasia is essential for the early diagnosis and treatment of this neurodegenerative motility disorder. Therefore, there is a need to find the main microRNAs (miRNAs) contributing to the mechanisms of achalasia. This study was conducted to determine some patterns of deregulated miRNAs in achalasia. This case-control study was performed on 52 patients with achalasia and 50 nonachalasia controls. The miRNA expression profiling was conducted on the esophageal tissue samples using the next-generation sequencing (NGS).

13p thiencuuchu 27-11-2021 9 2   Download

Document presentation of content: Introduction & key points, disease burden & endemicity, risk groups, diagnosis and differential diagnosis, management of strongyloidiasis, literature references, useful websites, queries and feedback from you.

15p vovanvovan2013 13-05-2016 56 1   Download

Document presentation of content: Methodology, literature review, and rationale, pathophysiology, epidemiology, natural history, risk factors, diagnosis and differential diagnosis, management of varices and hemorrhage, guidelines, further reading, and websites.

17p vovanvovan2013 13-05-2016 43 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Increased serum HO-1 in hemophagocytic syndrome and adult-onset Still's disease: use in the differential diagnosis of hyperferritinemia...

9p thulanh12 13-10-2011 46 2   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Differential diagnosis of Salmonella gallinarum and S. pullorum using PCR-RFLP

7p hoami_266 15-09-2011 46 6   Download

Endometriosis is a common gynaecological condition that sometimes presents to general surgeons as a lump in the abdomen. It can pose a diagnostic dilemma and should be in the differential diagnosis of lumps in the abdomen in females. Diagnosis is usually made on histology. We discuss a case of recurrent abdominal wall endometriosis following caesarian section. The incidence, pathophysiology, course, diagnosis, treatment and prevention of this condition are also reviewed.

3p truongthiuyen1 08-06-2011 59 5   Download

Food Poisoning S. aureus is among the most common causes of food-borne outbreaks of infection in the United States. S. aureus food poisoning results from the inoculation of toxin-producing S. aureus into food by colonized food handlers. Toxin is then elaborated in such growth-promoting food as custards, potato salad, or processed meats. Even if the bacteria are killed by warming, the heat-stable toxin is not destroyed. The onset of illness is rapid, occurring within 1–6 h of ingestion.

5p colgate_colgate 21-12-2010 69 4   Download

Diagnosis A diagnosis of botulism must be considered in patients with symmetric descending paralysis who are afebrile and mentally intact. The bulbar musculature is involved initially, but sensory findings are absent and, early on, deep tendon reflexes remain intact. The differential diagnosis of botulism and distinguishing features are listed in Table 134-2. Depending on season and other epidemiologic factors, West Nile virus infection may also be a consideration.

7p colgate_colgate 21-12-2010 101 5   Download

Differential Diagnosis The differential diagnosis between DIC and severe liver disease is challenging and requires serial measurements of the laboratory parameters of DIC. Patients with severe liver disease are at risk for bleeding and manifest laboratory features including thrombocytopenia (due to platelet sequestration, portal hypertension, or hypersplenism), decreased synthesis of coagulation factors and natural anticoagulants, and elevated levels of FDP due to reduced hepatic clearance. However, in contrast to DIC, these laboratory parameters in liver disease do not change rapidly.

5p thanhongan 07-12-2010 133 3   Download

Approach to the Patient: Thrombocytopenia The history and physical examination, results of the CBC, and review of the peripheral blood smear are all critical components in the initial evaluation of the thrombocytopenic patients (Fig. 109-2). The overall health of the patient and whether he/she is receiving drug treatment will influence the differential diagnosis. A healthy young adult with thrombocytopenia will have a much more limited differential diagnosis than an ill hospitalized patient who is receiving multiple medications.

5p thanhongan 07-12-2010 81 3   Download

The diagnosis of Hodgkin's disease is established by review of an adequate biopsy specimen by an expert hematopathologist. In the United States, most patients have nodular sclerosing Hodgkin's disease, with a minority of patients having mixed-cellularity Hodgkin's disease. Lymphocyte-predominant and lymphocyte-depleted Hodgkin's disease are rare. Mixed-cellularity Hodgkin's disease or lymphocyte-depletion Hodgkin's disease are seen more frequently in patients infected by HIV (Fig. 105-11).

5p thanhongan 07-12-2010 82 4   Download

Evaluation of an adequate biopsy by an expert hematopathologist is sufficient to make a diagnosis of follicular lymphoma. The tumor is composed of small cleaved and large cells in varying proportions organized in a follicular pattern of growth (Fig. 105-7). Confirmation of B cell immunophenotype and the existence of the t(14;18) and abnormal expression of BCL-2 protein are confirmatory. The major differential diagnosis is between lymphoma and reactive follicular hyperplasia. The coexistence of diffuse large B cell lymphoma must be considered.

5p thanhongan 07-12-2010 76 4   Download

Chronic lymphocytic leukemia. The peripheral white blood cell count is high due to increased numbers of small, well-differentiated, normal-appearing lymphocytes. The leukemia lymphocytes are fragile, and substantial numbers of broken, smudged cells are usually also present on the blood smear. If the primary presentation is lymphadenopathy and a lymph node biopsy is performed, pathologists usually have little difficulty in making the diagnosis of small lymphocytic lymphoma based on morphologic findings and immunophenotype.

6p thanhongan 07-12-2010 74 2   Download

Definition and Differential Diagnosis PRCA is characterized by anemia, reticulocytopenia, and absent or rare erythroid precursor cells in the bone marrow. The classification of PRCA is shown in Table 102-4. In adults, PRCA is acquired. An identical syndrome can occur constitutionally: Diamond-Blackfan anemia, or congenital PRCA, is diagnosed at birth or in early childhood and often responds to glucocorticoid treatment; a minority of patients have etiologic mutations in a ribosomal RNA processing gene called RPS19.

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Anemia of Acute and Chronic Inflammation/Infection (the Anemia of Chronic Disease) The anemia of chronic disease—which encompasses inflammation, infection, tissue injury, and conditions (such as cancer) associated with the release of proinflammatory cytokines—is one of the most common forms of anemia seen clinically and probably the most important in the differential diagnosis of iron deficiency, since many of the features of the anemia are brought about by inadequate iron delivery to the marrow, despite the presence of normal or increased iron stores.

5p thanhongan 07-12-2010 76 3   Download

The second condition is the anemia of chronic inflammation with inadequate iron supply to the erythroid marrow. The distinction between true irondeficiency anemia and the anemia associated with chronic inflammation is among the most common diagnostic problems encountered by clinicians (see below). Usually the anemia of chronic inflammation is normocytic and normochromic. The iron values usually make the differential diagnosis clear, as the ferritin level is normal or increased and the percent transferrin saturation and TIBC are typically below normal.

5p thanhongan 07-12-2010 76 3   Download

Noninvasive Breast Cancer Breast cancer develops as a series of molecular changes in the epithelial cells that lead to ever more malignant behavior. Increased use of mammography has led to more frequent diagnosis of noninvasive breast cancer. These lesions fall into two groups: ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (lobular neoplasia). The management of both entities is controversial. Ductal Carcinoma In Situ (DCIS) Proliferation of cytologically malignant breast epithelial cells within the ducts is termed DCIS.

5p konheokonmummim 03-12-2010 72 4   Download