Diagnostic screening
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Lung cancer is one of the most common type of cancer and, despite significant advances in screening and diagnosis approaches, a large proportion of patients at diagnosis still present advanced stages of the disease with distant metastasis and bad prognosis. Finding and validating biomarkers of lung cancer is therefore essential.
10p vishanshan 27-06-2024 1 1 Download
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Deleterious BRCA1/2 (BRCA) mutation raises the risk for BRCA mutation-related malignancies, including breast, ovarian, prostate, and pancreatic cancer. Germline variation of BRCA exhibits substantial ethnical diversity.
13p vishanshan 27-06-2024 2 1 Download
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Despite the existence of numerous studies investigating the diagnostic potential of blood microRNAs for colorectal cancer, the microRNAs under consideration vary widely, and comparative analysis of their diagnostic value is lacking. Consequently, this systematic review aims to identify the most effective microRNA blood tumor markers to enhance clinical decision-making in colorectal cancer screening.
15p vikoch 27-06-2024 1 1 Download
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Colorectal cancer (CRC) is the second leading cause of death among cancers in the United States. Although individuals diagnosed early have a greater than 90 % chance of survival, more than one-third of individuals do not adhere to screening recommendations partly because the standard diagnostics, colonoscopy and sigmoidoscopy, are expensive and invasive.
10p vioraclene 31-03-2024 1 1 Download
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Ebook "Chemical diagnostics: From bench to bedside" is concluded with the case of successful applications in the medical field. By using few drops of blood, newborn screening can identify babies with various genetic diseases soon after birth. Mass spectrometry has played a key role in metabolomics diagnostics in the clinics, allowing unambiguous identification of metabolites and their isoforms. Quantification at high precision can be achieved through various approaches.
204p tudohanhtau1006 29-03-2024 4 1 Download
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The diagnostic rate of Mendelian disorders in sequencing studies continues to increase, along with the pace of novel disease gene discovery. However, variant interpretation in novel genes not currently associated with disease is particularly challenging and strategies combining gene functional evidence with approaches that evaluate the phenotypic similarities between patients and model organisms have proven successful.
20p viellison 28-03-2024 1 1 Download
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Population screening for genetic risk of adult-onset preventable conditions has been proposed as an attractive public health intervention. Screening unselected individuals can identify many individuals who will not be identified through current genetic testing guidelines.
12p vicwell 29-02-2024 2 1 Download
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Next-generation sequencing (NGS) based population screening holds great promise for disease prevention and earlier diagnosis, but the costs associated with screening millions of humans remain prohibitive. New methods for population genetic testing that lower the costs of NGS without compromising diagnostic power are needed.
12p vicwell 29-02-2024 5 1 Download
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The diagnostic yield of genetic testing for inherited cardiac diseases is up to 40% and is primarily indicated for screening of at-risk relatives. Here, we evaluate the role of genomics in diagnosis and management among consecutive individuals attending a specialised clinic and identify those with the highest likelihood of having a monogenic disease.
14p vicwell 29-02-2024 4 1 Download
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Ebook "Clinical biochemistry" gives an overview of the acquisition of data, as well as concentrating on clinical aspects of the subject, giving detailed coverage of all conditions where clinical biochemistry is used in diagnosis and management. In common with other diagnostic specialties clinical biochemistry now uses an increasing number of techniques involving the 'new biology': these are covered in this book.
426p manmanthanhla0201 27-02-2024 3 1 Download
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Over-the-counter medication overdose is a difficult diagnostic challenge for many physicians as common drug screening assays cannot detect these substances. We present a case of acute psychosis, serotonin syndrome, and anticholinergic overdose-like properties in the setting of Coricidin HBP Cough & Cold tablets, known by their street name Triple-C.
4p vilazada 31-01-2024 4 2 Download
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Colposcopy is a tool for triaging screen positive women regardless of method used for cervical cancer screening. The objective of this study was to evaluate the diagnostic performance of colposcopy in the diagnosis of histologic cervical intraepithelial neoplasia 2+ (CIN 2+) at Jigme Dorji Wangchuck National Referral Hospital (JDWNRH), Thimphu, Bhutan.
8p vialfrednobel 23-12-2023 5 3 Download
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Part 1 book "Practical veterinary diagnostic imaging" includes content: Essential mathematics and physics, the principles of physics used in radiography, inside the atom, the X ray tube, diagnostic equipment, production of X rays, the effects of radiation, control of the primary beam and scatter, radiographic film, intensifying screens and cassettes.
120p oursky07 24-10-2023 5 3 Download
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A recent theory supports that high-grade serous epithelial ovarian cancer derives from the fimbrial end of the fallopian tube and during the last decade, a few studies have examined the fallopian tube cytology.
8p vischultz 20-10-2023 5 1 Download
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Part 1 book "Christensen’s physics of diagnostic radiology" includes content: Radiation, production of X-rays, X-ray generators, basic interactions between X-rays and matter, attenuation, X-ray beam restrictors, luminescent screens, physical characteristics of X-ray film & film processing, photographic characteristicsof X-ray film, fluoroscopic imaging, viewing & recording fluoroscopic image.
207p oursky06 17-10-2023 5 1 Download
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The prognosis of patients with colorectal cancer is related to early detection. However, commonly used screening markers lack sensitivity and specificity. In this study, we identified diagnostic methylation sites for colorectal cancer.
12p vioracle 29-09-2023 8 3 Download
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Advanced diagnostic systems and screening services for health care have made it possible to improve the detection of congenital cardiovascular abnormalities, including coronary artery variations. Many coronary artery fistulas are congenital, and this can also be reported in patients with normal heart anatomy.
3p viintuit 26-09-2023 2 0 Download
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Existing screening tools for early detection of autism are expensive, cumbersome, time- intensive, and sometimes fall short in predictive value. In this work, we sought to apply Machine Learning (ML) to gold standard clinical data obtained across thousands of children at-risk for autism spectrum disorder to create a low-cost, quick, and easy to apply autism screening tool.
8p visteverogers 24-06-2023 4 2 Download
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The study sought to characterize the evaluation of patients who present following detection of an abnormal pulse using Apple Watch. Materials and Methods: We conducted a retrospective review of patients evaluated for abnormal pulse detected using Apple Watch over a 4-month period.
5p vighostrider 25-05-2023 7 2 Download
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Primary open-angle glaucoma (POAG) continues to be a poorly understood disease. Although there were multiple researches on the identification of POAG biomarkers, few studies systematically revealed the immune-related cells and immune infiltration of POAG.
16p vihagrid 30-01-2023 9 3 Download