Dipeptidyl peptidase IV
-
Nghiên cứu dưới đây cho thấy tác dụng ức chế in vitro của các cao chiết lá chùm ruột (Phyllanthus acidus) đối với hoạt động của các enzym liên quan đến bệnh đái tháo đường và cao huyết áp như α-glucosidase, α-amylase, dipeptidyl peptidase IV (DPP-IV) và angiotensin-converting enzyme (ACE). Các chiết xuất cao từ lá chùm ruột của cao ethanol toàn phần (TP) và các cao phân đoạn như ether ethylic (EE), ethyl acetate (EA), n-butanol (BU) và nước (WA) đã được thử nghiệm với các enzyme trên.
4p viisac 14-09-2023 5 3 Download
-
Dipeptidyl peptidase-IV (DPP-IV) is suggested to contribute to the pathogenesis of several autoimmune diseases. The aim of this study was to evaluate the association of DPP-IV presence in blood plasma and mononuclear cells with the disease activity in rheumatoid arthritis (RA).
7p vioregon2711 22-02-2021 9 1 Download
-
CD26/dipeptidyl peptidase IV (DPPIV) is a multifunctional membrane protein with a key role in T-cell biology and also serves as a marker of aggressive cancers, including T-cell malignancies. Methods: Versican expression was measured by real-time RT-PCR and Western blots. Gene silencing of versican in parental Karpas 299 cells was performed using transduction-ready viral particles.
11p vijennie2711 29-09-2020 12 1 Download
-
It is still difficult to detect and diagnose early adenocarcinoma of the esophagogastric junction (EGJ) using conventional endoscopy or image-enhanced endoscopy.
9p vikuala271 13-06-2020 5 0 Download
-
The patterns and determinants of saxagliptin use among patients with type 2 diabetes mellitus (T2DM) are unknown in real-world settings. We compared the characteristics of T2DM patients who were new initiators of saxagliptin to those who were new initiators of non-dipeptidyl peptidase-4 (DPP-4) inhibitor oral anti-diabetic drugs (OADs) and identified factors associated with saxagliptin use.
16p vienzym2711 03-04-2020 8 0 Download
-
The present work was carried out for the production of dipeptidyl peptidase IV (DPP IV; EC 3.4.14.5) using Aspergillus Penicillium, and Rhizopus strains under solid state fermentation conditions.
7p vivant2711 01-02-2019 20 1 Download
-
Dipeptidyl peptidase IV (DP IV, CD26) plays an essential role in the activation and proliferation of lymphocytes, which is shown by the immunosuppressive effects of syn-thetic DP IV inhibitors. Similarly, both human immuno-deficiency virus-1 (HIV-1) Tat protein and the N-terminal peptide Tat(1–9) inhibit DP IV activity and T cell prolifer-ation. Therefore, the N-terminal amino acid sequence of HIV-1 Tat is important for the inhibition of DP IV.
10p fptmusic 16-04-2013 29 2 Download
-
The prolyl oligopeptidase (POP) family of serine proteases includes prolyl oligopeptidase, dipeptidyl peptidase IV, acylaminoacyl peptidaseandoligopeptidase B.The enzymes of this family specifically hydrolyze oligopeptides with less than 30 amino acids.Many of the POP family enzymes have evoked pharmaceutical interest as they have roles in the regulationof peptide hormones and are involved in a variety of diseases such as dementia, trypanosomiasis and type 2 diabetes.
11p dell39 03-04-2013 52 2 Download
-
The dipeptidyl peptidase IV gene family contains the four peptidases dipept-idyl peptidase IV, fibroblast activation protein, dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Dipeptidyl peptidase IV and fibroblast activation protein are involved in cell–extracellular matrix interactions and tissue re-modeling.
14p inspiron33 26-03-2013 37 3 Download
-
Dipeptidyl peptidase IV (DPP IV, CD26, EC 3.4.14.5) serves as a model aimed at elucidating protein sorting signals. We identify here, by MS, sev-eral tyrosine-phosphorylated proteins in a rat liver Golgi⁄endosome (G⁄E) fraction including DPP IV. We show that a pool of DPP IV is tyrosine-phosphorylated.
12p inspiron33 26-03-2013 43 4 Download
-
We previously showed that the rat dipeptidyl peptidase IV (rDPP IV) monoclonal antibody (mAb) 6A3 greatly inhibits the pericellular polymeric fibronectin-mediated metastatic cancer cell adhesion to rDPP IV. L 311 QWLRRI in rDPP IV has been proposed as the putative fibronectin-binding site.
12p viettel02 20-02-2013 40 2 Download
-
Of the 600+ known proteases identified to date in mammals, a significant percentage is involved or implicated in pathogenic and cancer processes. The dipeptidyl peptidase IV (DPIV) gene family, comprising four enzyme members [DPIV (EC 3.4.14.5), fibroblast activation protein, DP8 and DP9] and two nonenzyme members [DP6 (DPL1) and DP10 (DPL2)], are inter-esting in this regard because of their multiple diverse functions,
19p mobifone23 18-01-2013 31 3 Download
-
Kato et al. Organic and Medicinal Chemistry Letters 2011, 1:7 http://www.orgmedchemlett.
7p dauphong13 10-02-2012 50 4 Download
-
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cells
12p dauphong2 23-12-2011 37 2 Download
-
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Dipeptidyl peptidase IV activity and/or structure homologs: Contributing factors in the pathogenesis of rheumatoid arthritis?
17p thulanh12 13-10-2011 43 3 Download