Direct antiglobulin test

Hyperbilirubinaemia is a major cause of neonatal morbidity. Early identification of those infants most at risk might allow the development of targeted primary preventative therapy and follow-up. The objective of this study was to assess whether arterial umbilical cord bilirubin (aUCB) level at delivery predicts the development of neonatal jaundice in term deliveries.

6p vidr2711 19-02-2020 27 1   Download

Ineffective Hemopoiesis There is an accumulation of unconjugated bilirubin in plasma due to the death of nucleated red cells in the marrow (ineffective erythropoiesis). Other evidence for this includes raised urine urobilinogen, reduced haptoglobins and positive urine hemosiderin, and a raised serum lactate dehydrogenase. A weakly positive direct antiglobulin test due to complement can lead to a false diagnosis of autoimmune hemolytic anemia. Causes of Cobalamin Deficiency Cobalamin deficiency is usually due to malabsorption. The only other cause is inadequate dietary intake.

5p thanhongan 07-12-2010 56 2   Download