Direct oral anticoagulation
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Anticoagulants are commonly associated with hemorrhagic complications. However, rare hypersensitivity drug reactions associated with direct oral anticoagulants (DOACs) in form of cutaneous reactions such as urticaria as well as angioedema can have significant burden owing to increase in morbidity and mortality.
5p viintuit 26-09-2023 1 0 Download
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Coronavirus Disease 2019 (COVID-19) is a pandemic afecting all countries in the world. Italy has been particularly aficted by the health emergency, and since the peak phase has passed, major concern regarding medium to long term complications due to COVID-19 is arising. Little is known in literature regarding thromboembolic complications once healed after COVID-19.
4p vimichigan2711 26-03-2021 13 2 Download
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Apixaban effectively lowers the risk of ischemic stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Systemic exposure to a given apixaban dose depends on multiple clearance pathways.
6p vimax2711 27-03-2020 12 1 Download
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A historical cohort analysis of the Japan medical data center (JMDC) claims databases was performed to compare the incidence rates of bleeding events with warfarin (WF) versus direct oral anticoagulant (DOAC) treatment in patients with non-valvular atrial fibrillation. The aim of this study is to clarify the risk factors for bleeding events in younger patients newly treated with WF or DOAC in clinical practice setting.
8p vihasaki2711 12-11-2019 16 0 Download
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Direct oral anticoagulants (DOACs) are used in anticoagulant therapy. The purpose of this study was to evaluate the association of DOAC-induced gastrointestinal (GI) and nervous system hemorrhage using the FDA's Adverse Event Reporting System (FAERS) database and the Japanese Adverse Drug Event Report (JADER) database.
9p vinasaki2711 12-11-2019 13 0 Download