![](images/graphics/blank.gif)
Disease diagnoses
-
To evaluate the results of cerebral hemorrhage surgery due to cerebrovascular accident at Viet Tiep Hospital. Patients and methods: The study included 31 patients diagnosed with cerebral hemorrhage due to cerebrovascular accident, who were treated with surgery at Viet Tiep Hospital from January 2023 to June 2023.
6p
viwalton
02-07-2024
1
0
Download
-
Autologous stem-cell transplantation (ASCT) remains a beneficial approach for patients with newly diagnosed multiple myeloma (NDMM) in the age of novel therapeutic agents. Nevertheless, limited real-world data is available to establish criteria for identifying high-risk ASCT patients.
11p
vishanshan
27-06-2024
1
1
Download
-
The numbers of registered clinical trials show an upward trend. Age disparities between trial participants and diagnosed disease population are present in BPCRL cancer trials and appear to be increasing over time. Equitable participation in clinical trials on the basis of age is crucial for advancing medical knowledge and evaluating the safety and efficacy of new treatments that are generalizable to aging populations.
8p
vishanshan
27-06-2024
2
1
Download
-
Smoking is a major risk factor for multiple gastrointestinal cancers, and adversely affects peptic ulcer disease, gastroesophageal reflux, pancreatitis and Crohn’s disease. Despite key recommendations for diagnosing and treating tobacco use disorder in healthcare settings, the degree to which this is implemented in Gastroenterology (GI) clinics is unknown.
10p
vishanshan
27-06-2024
1
1
Download
-
Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio, and duodenal carcinoma, are frequently diagnosed in an advanced stage and are associated with poor overall survival.
12p
vishanshan
27-06-2024
1
1
Download
-
In this study, we attempted to non-invasively diagnose glioma development and the presence of IDH mutations using multivariate analysis of the plasma mid-infrared absorption spectra for a comprehensive and sensitive view of changes in blood components associated with the disease and genetic mutations.
14p
vikoch
27-06-2024
1
1
Download
-
Pediatric low-grade glioma (pLGG) is essentially a single pathway disease, with most tumors driven by genomic alterations affecting the mitogen-activated protein kinase/ERK (MAPK) pathway, predominantly KIAA1549::BRAF fusions and BRAF V600E mutations. This makes pLGG an ideal candidate for MAPK pathway-targeted treatments.
11p
vikoch
27-06-2024
1
1
Download
-
Endocrine conditions requiring surgical intervention in the pediatric age group are uncommon. When diagnosed, they are the source of great in terest and, often, considerable debate. This is understandable, since few centers and even fewer individual surgeons can draw on vast experience of this subject. The great divergence of opinion regarding management is also understandable in that pediatric endocrine lesions often differ considerably from their adult counterparts in histology, natural history and response to treatment.
155p
vimeyers
29-05-2024
2
2
Download
-
Patients diagnosed with high-grade serous ovarian cancer (HGSOC) who received initial debulking surgery followed by platinum-based chemotherapy can experience highly variable clinical responses. A small percentage of women experience exceptional long-term survival (long term (LT), 10+ years), while others develop primary resistance to therapy and succumb to disease in less than 2 years (short term (ST)).
17p
vibransone
28-03-2024
2
1
Download
-
Classifying pathogenicity of missense variants represents a major challenge in clinical practice during the diagnoses of rare and genetic heterogeneous neurodevelopmental disorders (NDDs). While orthologous gene conservation is commonly employed in variant annotation, approximately 80% of known disease-associated genes belong to gene families.
12p
vibransone
28-03-2024
3
2
Download
-
Gut microbiome dysbiosis has been demonstrated in subjects with newly diagnosed and chronic inflammatory bowel disease (IBD). In this study we sought to explore longitudinal changes in dysbiosis and ascertain associations between dysbiosis and markers of disease activity and treatment outcome.
13p
vioraclene
31-03-2024
4
2
Download
-
Clinical laboratory (lab) tests are used in clinical practice to diagnose, treat, and monitor disease conditions. Test results are stored in electronic health records (EHRs), and a growing number of EHRs are linked to patient DNA, offering unprecedented opportunities to query relationships between genetic risk for complex disease and quantitative physiological measurements collected on large populations.
16p
vibransone
28-03-2024
4
2
Download
-
Clinical interpretation of genetic variants in the context of the patient’s phenotype is becoming the largest component of cost and time expenditure for genome-based diagnosis of rare genetic diseases. Artificial intelligence (AI) holds promise to greatly simplify and speed genome interpretation by integrating predictive methods with the growing knowledge of genetic disease.
19p
vibransone
28-03-2024
3
2
Download
-
Genomic variants which disrupt splicing are a major cause of rare genetic diseases. However, variants which lie outside of the canonical splice sites are difficult to interpret clinically. Improving the clinical interpretation of non-canonical splicing variants offer a major opportunity to uplift diagnostic yields from whole genome sequencing data.
11p
viellison
28-03-2024
2
2
Download
-
Small intestinal neuroendocrine tumors (SI-NETs) are the most common neoplasms of the small bowel. The majority of tumors are located in the distal ileum with a high incidence of multiple synchronous primary tumors. Even though up to 50% of SI-NET patients are diagnosed with multifocal disease, the mechanisms underlying multiple synchronous lesions remain elusive.
12p
viellison
28-03-2024
1
1
Download
-
The cerebrospinal fluid (CSF) features a unique immune cell composition and is in constant contact with the brain borders, thus permitting insights into the brain to diagnose and monitor diseases. Recently, the meninges, which are filled with CSF, were identified as a neuroimmunological interface, highlighting the potential of exploring central nervous system (CNS) immunity by studying CNS border compartments.
12p
viellison
28-03-2024
5
2
Download
-
The HCMC Oncology Hospital is a leading hospital in South Vietnam for diagnosing and treating cancer diseases. Therefore, this article aims to identify malnutrition status and related factors in gastric cancer patients undergoing chemotherapy treatment at HCMC Oncology Hospital in 2022. We also provided information or counseling in the high-risk groups.
11p
vilarry
12-03-2024
2
2
Download
-
In this article, we report a case of a female patient having generalized cutaneous lesions. She was initially diagnosed with SLE and received treatment at Department of Allergy, Center of Dermato-Venerology and Allergy, 108 Military Central Hospital.
4p
vilarry
12-03-2024
5
2
Download
-
Copy-number variations (CNVs) have been associated with rare and debilitating genomic disorders (GDs) but their impact on health later in life in the general population remains poorly described. Methods Assessing four modes of CNV action, we performed genome-wide association scans (GWASs) between the copy-number of CNV-proxy probes and 60 curated ICD-10 based clinical diagnoses in 331,522 unrelated white British UK Biobank (UKBB) participants with replication in the Estonian Biobank.
24p
vicwell
29-02-2024
3
2
Download
-
To diagnose the full spectrum of hereditary and congenital diseases, genetic laboratories use many different workfows, ranging from karyotyping to exome sequencing. A single generic high-throughput workflow would greatly increase efciency. We assessed whether genome sequencing (GS) can replace these existing workflows aimed at germline genetic diagnosis for rare disease.
11p
vicwell
29-02-2024
4
2
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)