Disease effectively

Pancreatic lipase is one of the safest targets of anti-obesity drugs. To date, orlistat is the only pancreatic lipase inhibitor approved for the long-term treatment of obesity. Therefore, there is an elevated need to find new drugs for this disease.

6p viharuno 03-01-2025 0 0   Download

Periodontitis is the most common form of periodontal disease, greatly affecting the aesthetics, function as well as patient’s quality of life. This study aims to compare the effect of two nonsurgical periodontal modalities: one-stage full-mouth and partial-mouth protocols for periodontitis.

7p viharuno 03-01-2025 0 0   Download

Physical activity (PA) plays a vital role in both physical and mental development of adolescents. This study aims to determine adolescent physical activity status and several related factors and to preliminarily evaluate its effect on the development of adolescent height and weight.

8p viuchiha 03-01-2025 0 0   Download

The core list presents a list of minimum medicine needs for a basic health‐care system, listing the most efficacious, safe and cost‐effective medicines for priority conditions. Priority conditions are selected on the basis of current and estimated future public health relevance, and potential for safe and cost‐effective treatment. The complementary list presents essential medicines for priority diseases, for which specialized diagnostic or monitoring facilities, and/or specialist medical care, and/or specialist training are needed.

45p kikyou751998 23-05-2012 444 38   Download

The current study sought to determine: If there is a correlation between conventional measures of lung function such as Forced Expiratory Volume in one second (FEV1) and less conventional measures such as airways expired NO level (eNO), electrodermal measures, TCM enquiry and BHT; If any of the lung function measures are able to distinguish between asthmatic and healthy subjects; If the use of a rye grass extract is better than placebo in improving requirements for bronchodilator medication, peak flow, forced expiratory volume in one second or quality of life in mild to moderate childhood a...

262p runthenight05 01-03-2023 10 5   Download

The thesis is structured as follows: In Chapter 1, the scientific literature is summarized within the scope of this study. Chapter 2 provides a comprehensive overview of the principles of the applied computational approaches in this study. Chapter 3 identifies the important residues of the LsIA/α7 nAChR complex that affect the interactions between the toxin and the membrane protein due to C-terminal carboxylation of LsIA. The effects of C-terminal modification of LsIA on interactions with α3β2 nAChR, involved in cardiovascular diseases, were also investigated in Chapter 4.

234p runthenight04 02-02-2023 11 3   Download

The plants are vigorous, dome shaped and compact. These guavas are cultivated across the Allahabad, Uttar Pradesh region in the northern belt of India. Apple guava is cultivated today on almost 1000 hectares of land mainly under Kaushambi and Kaurihar -II districts of Allahabad] . The fruit is known for its medical properties such that during the winter season because it neutralizes disease symptoms.

5p chauchaungayxua11 23-03-2021 32 3   Download

The objectives of the thesis: Identify the pathogenicity potential and classificate at species level of Colletotrichum spp. isolated from hot chilli in Vietnam; produce stable oligochitosan-silica nano, which potentially highly induced effectively the systemic resistance against anthranose disease on hot chilli, based on the combination of low molecular weight chitosan with nano silica.

28p capheviahe27 23-02-2021 30 4   Download

Finger millet or ragi is the primary food source for millions of people in tropical dry land regions of Africa and Asia. Two field experiments were conducted to study the genotypic variation for silicon accumulation and the effect of foliar applied silicic acid on growth, nutrient uptake and blast disease resistance of ragi. Study showed a significant varietal variation for Si accumulation with an average Si content of 1.67 % in the above ground part.

11p angicungduoc6 22-07-2020 13 3   Download

Describing the epidemiological characteristics of Chronic obstructive pulmonary disease in Que Vo and Thuan Thanh districts, Bac Ninh province in 2015. Analyzing some factors related to Chronic obstructive pulmonary disease in the studied area. Evaluating the effectiveness of a number of intervention measures against Chronic obstructive pulmonary disease in Que Vo district, Bac Ninh province.

28p cothumenhmong6 17-07-2020 27 2   Download

A field experiment was conducted at Boodamanahalli village, (Bangalore rural district) to know the effect of tikka disease, caused together by Cercospora arachidicola and Cercosporidium personatum on biochemical parameters viz., total sugars, total phenols and total proteins as influenced by different sowing dates in groundnut. It included two varieties, TMV-2 a highly susceptible one and GBPD-4 a resistant with nine sowing dates starting from December 2008 to August 2009 at monthly intervals.

9p chauchaungayxua6 26-06-2020 19 2   Download

The efficacy of some fungicides like carbendazim 12 % + mancozeb 63 % WP, difenoconazole 25 EC, propiconazole 25 EC along with commonly used fungicides viz., mancozeb 75 WP, propineb 70 WP, copper-oxy-chloride 50 % WP and one botanical Azadirachta indica (neem) leaf extract (20%) were tested against early blight of tomato cv. Abhinav at Agricultural Research Station, Ladol, Gujarat. A variant with no application of fungicide was used as a control. All fungicide treatments reduce the disease intensity as compared to untreated check.

7p nguaconbaynhay5 16-05-2020 18 2   Download

Schistosomiasis is an endemic disease in Egypt caused by the trematode Schistosoma which has different species. c the best known form of chronic disease with a wide range of clinical manifestations. The pathogenesis of schistosomiasis is related to the host cellular immune response. This leads to granuloma formation and neo angiogenesis with subsequent periportal fibrosis manifested as portal hypertension, splenomegaly and esophageal varices. Intestinal schistosomiasis is another well identified form of chronic schistosomal affection.

8p kethamoi1 17-11-2019 30 2   Download

General objective of the study: Survey and assessment of hemorrhage appear on a mudskipper farm in Bac Lieu province. Identifying characteristics of Pathology in fish pathogens which proposed solutions to prevent and treat the disease effectively.

27p change05 08-06-2016 39 5   Download

Researching this thesis with a view to: describe the knowledge, attitude and practice (KAP) of farmer exposure to pesticides; determine disease model and describe some factors related to farmer health in cultivating tea; construction and appreciate of effect of interfere model on human health protection suitably for current conditions in Thai Nguyen.

24p nguyenthiminh32 12-07-2014 131 5   Download

Eukaryotic ribonuclease (RNase) H2 consists of one catalytic and two accessory subunits. Several single mutations in any one of these subunits of human RNase H2 cause Aicardi–Goutie`res syndrome. To examine whether these mutations affect the complex stability and activity of RNase H2, three mutant proteins of His-tagged Saccharomyces cerevisiaeRNase H2 (Sc-RNase H2*) were constructed. Sc-G42S*, Sc-L52R*, and Sc-K46W* contain single mutations in Sc-Rnh2Ap*, Sc-Rnh2Bp*, and Sc-Rnh2Cp*, respectively....

14p research12 29-04-2013 40 1   Download

Diagnostic tests by molecular biology is made for studying the relations among Fusarium species for linking production of proteins, degree of relationship and occurrence of malformation. Determination of proteins for isolates causing-disease by SDS-PAGE explained there’s specific band for each fungus and there are common bands among some isolates of fungi. Since, band with MW 30 KDa represented only in F. proliferatum and F. oxysporum and F. subgluti-nans respectively. This band considered as specific band for these isolates, which released high patho-genisity effect.

7p zingzing09 24-04-2013 59 3   Download

Cyclin-dependent kinase-5 (Cdk5) is a serine/threonine kinase activated by its neuron-specific activator, p35, or its truncated form, p25. It has been proposed that the deregu-lation of Cdk5 activity by association with p25 in human brain tissue disrupts the neuronal cytoskeleton and may be involved in neurodegenerative diseases such as Alzheimer’s disease.

8p research12 23-04-2013 32 2   Download

Intravenous iron, used for the treatment of anemia in chronic renal failure andother diseases, represents a possible source of free iron in tissue cells, particularly in the liver. In this study we examined the effect of different sources of intravenous iron (IVI) on the labile iron pool (LIP) which represents the nonferritin-bound, redox-active iron that is implicated in oxidative stress and cell injury. Furthermore, we examined the role of the LIP for the synthesis of ferritin.

8p tumor12 20-04-2013 49 4   Download

Mitochondrial cytochromecoxidase is a key protonmotive component of the respiratory chain. Mutations in the mito-chondrially-encoded subunits of the complex have been reported in associationwith a range of diseases. In this work we used yeast and bacterial mutants to assess the effect of humanmutations insubunit 1 (L196I) andsubunit 3 (G78S, A200T,DF94–F98, F251L and W249Stop).

9p tumor12 20-04-2013 35 1   Download