Diseases worldwide

Asthma, a pervasive chronic inflammatory ailment of the respiratory system, remains a global health conundrum. The Global Burden of Disease Study (GBD) of 2019 underscores its widespread impact, revealing that asthma afflicts 262 million individuals worldwide, translating into an age-standardized prevalence of 3,416 per 100,000 population.

11p vinara 11-01-2025 1 1   Download

Synovial sarcoma is the fourth most common type of soft-tissue sarcoma, accounting for 2.5%-10.5% of all primary soft-tissue neoplasms worldwide. This disease most often affects the extremities, 80%-95% of cases, of adolescents and young adults (15-40 years of age).

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Chronic kidney disease (CKD) is increasingly recognized as a major health problem worldwide. Objectives: (1) To evaluate the malondialdehyde concentration and kynurenine and tryptophan ratio for differences between CKD patients and healthy controls. (2) To analyze the relationship and correlation between these biomarker indexes and some risk factors of CKD.

7p vihatake 06-01-2025 7 2   Download

Hypertension is the leading disease in Vietnam and the leading risk factor for noncommunicable diseases worldwide. It is a manageable and treatable condition, according to the guidelines of the Ministry of Health and the clinical practice recommendations of the Vietnam Society of Cardiovascular and the Vietnam Society of Hypertension.

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Hemoglobinopathy is the most common monogenic disease worldwide. The aims of the current study were: (1) to investigate some hematological characteristics of patients with hemoglobinopathies; and (2) to detect the mutation of α-globin and β-globin genes, as well as the association between genotype and degree of anemia.

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Hepatitis B infection remains a global health problem, with progression to acute-chronic hepatitis, severe liver failure, and death making hepatitis B one of the most serious infections worldwide. The disease is most widely transmitted from an infected mother to her baby, after exposure to infected blood or body fluids or unsafe sexual contact.

6p viharuno 03-01-2025 1 1   Download

Neurodegenerative disorders, such as Huntington’s, Alzheimer’s, and Parkinson’s diseases, affect millions of people worldwide and currently there are few effective treatments and no cures for these diseases. Transgenic mice expressing human transgenes for huntingtin, amyloid precursor protein, and other genes associated with familial forms of neurodegenerative disease in humans provide remarkable tools for studying neurodegeneration because they mimic many of the pathological and behavioural features of the human conditions. ...

15p awards 06-04-2013 39 4   Download

Streptococcus pneumoniaeis one of the major pathogens worldwide. The use of currently available antibiotics to treat pneumococcal diseases is ham-pered by increasing resistance levels; also, capsular polysaccharide-based vaccination is of limited efficacy. Therefore, it is desirable to find targets for the development of new antimicrobial drugs specifically designed to fight pneumococcal infections.

13p inspiron33 23-03-2013 46 3   Download

Tuberculosis (TB) continues to be a major cause of morbidity and mortal-ity worldwide. The increasing emergence and spread of drug-resistant TB poses a significant threat to disease control and calls for the urgent devel-opment of new drugs. The tryptophan biosynthetic pathway plays an important role in the survival of Mycobacterium tuberculosis.

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Colorectal cancer (CRC) is a major public health issue worldwide, and novel tumor markers may contribute to its efficient management by helping in early detection, prognosis or surveillance of disease. The aim of our study was to identify new serum biomarkers for CRC, and we followed a phased biomarker discovery and validation process to obtain an accurate preliminary assessment of potential clinical utility.

15p cosis54 08-12-2012 52 2   Download

Streptococcal disease caused by Streptococcus iniae is without doubt one of the major bacterial diseases in fish. It has been reported to cause significant mortality in more than 12 different aquaculture species. Its distribution is worldwide in both freshwater and marine environments. The annual impact to aquaculture has been estimated to be over US$100 million. However, in the past, very few reports have described its presence in Asia.

15p vohnongnguyen 23-03-2010 207 44   Download