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Disorders associated
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Obstructive Sleep Apnea is a prevalent disorder that affects individuals across various age groups and lifestyles. Although OSA is commonly associated with obesity and sedentary lifestyles, it can also affect physically active individuals. Bodybuilding and obstructive sleep apnea should be interconnected due to factors such as changes in body composition and weight fluctuations.
6p
vikoch
27-06-2024
1
1
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Leptomeningeal metastasis (LM) of small cell lung cancer (SCLC) is a highly detrimental occurrence associated with severe neurological disorders, lacking effective treatment currently. Proteolysis-targeting chimeric molecules (PROTACs) may provide new therapeutic avenues for treatment of podophyllotoxin derivatives-resistant SCLC with LM, warranting further exploration.
12p
vishanshan
27-06-2024
2
1
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Helicobacter pylori is a bacterium associated with gastric diseases and disorders of the upper gastrointestinal tract. The gram-negative bacterium Helicobacter pylori is known as a persistent colonizer of the human stomach, and this bacteria is also involved in extra-intestinal diseases.
11p
vikoch
27-06-2024
2
1
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This study was to explore the causal associations of sleep traits including sleep duration, snoring, chronotype, sleep disorders, getting up in the morning, sleeplessness/insomnia and nap during day with the risk of thyroid cancer based on Mendelian randomization (MR) analysis.
11p
vishanshan
27-06-2024
1
1
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Determine the rate of Autism Spectrum Disorder in children between the ages of 18 and 36 months by utilizing the M-CHAT-R scale at the clinic of Can Tho Children's Hospital. And identify the associated risk factors for that rate of Autism Spectrum Disorder.
8p
vikoch
27-06-2024
1
1
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Female gynecological cancers represent a serious public health problem, with 1,398,601 new diagnoses and 671,875 deaths per year worldwide. Antipsychotics are often used in psychiatric disorders, including schizophrenia, bipolar disorder, and major depression. It is estimated that the prescription of these drugs is linked to 1,800 deaths a year in the United States, but their association with cancer remains controversial.
10p
vikoch
27-06-2024
1
1
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Observational studies have explored the association of psychiatric disorders and the risk of brain cancers. However, the causal effect of specific mental illness on glioma remains elusive due to the lack of solid evidence.
10p
vikoch
27-06-2024
2
1
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Part 2 book Dermatology - An illustrated colour text" includes content: Disorders of nails; vascular and lymphatic diseases; urticaria and angioedema, blistering disorders, connective tissue diseases, vasculitis and the reactive erythemas; Skin changes in internal conditions, drug eruptions, associations with malignancy, neurocutaneous disorders and other syndromes.
145p
zizaybay1101
30-04-2024
3
2
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Ebook "Protein folding and misfolding: Neurodegenerative diseases" is to review the molecular events initiated by unfolded or misfolded proteins leading to cell death via the development of pathological inclusions, with special emphasis on the macromolecular associations of the malfolded proteins into characteristic ultrastructures found in the cases of neurological disorders, some of them are shown in this issue.
284p
ladongphongthanh1008
22-04-2024
3
2
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In ebook "Myosins: A superfamily of molecular motors" the association of myosins with diseases including neurological disorders, immunodeficiencies, cardiomyopathies, hearing and vision loss testify to the importance of understanding the biochemical properties and cellular roles of myosins. The 16 chapters in this volume summarize the tremendous progress made in studying members of the myosin superfamily in recent years and offer critical insight into what future research will yield.
498p
ladongphongthanh1008
22-04-2024
4
2
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Part 1 book 'Evidence-Based geriatric nursing protocols for best practice" includes content: Urinary incontinence; catheter associated urinary tract infection prevention; oral health care; managing oral hydration; nutrition; mealtime difficulties; family caregiving; issues regarding sexuality; substance misuse and alcohol use disorders; mistreatment detection; health care decision making,... and other contents.
360p
muasambanhan10
03-04-2024
3
2
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Rheumatoid arthritis is a common autoimmune disorder influenced by both genetic and environmental factors. Epigenome-wide association studies can identify environmentally mediated epigenetic changes such as altered DNA methylation.
12p
vibransone
28-03-2024
3
2
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Advanced age is associated with cognitive and physical decline and is a major risk factor for a multitude of disorders. There is also a gap in life expectancy between males and females. DNA methylation differences have been shown to be associated with both age and sex.
11p
vibransone
28-03-2024
2
2
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Classifying pathogenicity of missense variants represents a major challenge in clinical practice during the diagnoses of rare and genetic heterogeneous neurodevelopmental disorders (NDDs). While orthologous gene conservation is commonly employed in variant annotation, approximately 80% of known disease-associated genes belong to gene families.
12p
vibransone
28-03-2024
3
2
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Fecal microbiota transplantation (FMT) has demonstrated efficacy in treating inflammatory bowel diseases and irritable bowel syndrome in an increasing number of randomized controlled trials. Recently published data gives striking insights into the factors associated with FMT success paving the road for the use of precision medicine in gastrointestinal disorders.
4p
vibransone
28-03-2024
9
2
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Genome-wide association studies have shown unequivocally that common complex disorders have a polygenic genetic architecture and have enabled researchers to identify genetic variants associated with diseases. These variants can be combined into a polygenic risk score that captures part of an individual’s susceptibility to diseases.
11p
vibransone
28-03-2024
6
1
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Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex heritability and higher prevalence in males. The neonatal epigenome has the potential to reflect past interactions between genetic and environmental factors during early development and influence future health outcomes.
25p
vibransone
28-03-2024
5
1
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Disagreements over genetic signatures associated with disease have been particularly prominent in the field of psychiatric genetics, creating a sharp divide between disease burdens attributed to common and rare variation, with study designs independently targeting each.
14p
vioraclene
31-03-2024
2
2
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The bromodomain containing 1 (BRD1) gene has been implicated with transcriptional regulation, brain development, and susceptibility to schizophrenia and bipolar disorder. To advance the understanding of BRD1 and its role in mental disorders, we characterized the protein and chromatin interactions of the BRD1 isoforms, BRD1-S and BRD1-L.
20p
vioraclene
31-03-2024
3
1
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Patients with certain genetic diseases, such as autism spectrum disorder, have increased rates of de novo mutations within some protein-coding genes. We introduce the VARiant PRIoritization SuM (VARPRISM), a software package which incorporates functional variant prioritization information to improve the power to detect de novo mutations influencing disease risk.
11p
vioraclene
31-03-2024
1
1
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