Diverse synthetic

In ebook "Synthetic and biophysical studies on the tridachiahydropyrone family of natural products" methodology for the palladium-catalysed cyanation of vinyl halides with acetone cyanohydrin was developed. Conditions were optimised using β-bromostyrene, and shown to be applicable to a range of diverse substrates.

147p tracanhphuonghoa1007 22-04-2024 4 3   Download

Ebook "Organo-di-metallic compounds (or reagents): Synergistic effects and synthetic applications" presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science.

210p nhanphanguyet 28-01-2024 2 2   Download

Carbon dots (CDs) are the most promising members of the carbon family with superior properties such as ultrasmall size, high solubility, low cytotoxicity, and inherent fluorescence endows their potential for diverse applications.

10p vicedric 08-02-2023 4 4   Download

The CRISPR/Cas9 system provides bacteria and archaea with molecular immunity against invading phages and conjugative plasmids. Recently, CRISPR/Cas9 has been used for targeted genome editing in diverse eukaryotic species.

11p viaristotle 29-01-2022 9 0   Download

In maize hybrid breeding, complementary pools of parental lines with reshuffled genetic variants are established for superior hybrid performance. To comprehensively decipher the genetics of heterosis, we present a new design of multiple linked F1 populations with 42,840 F1 maize hybrids, generated by crossing a synthetic population of 1428 maternal lines with 30 elite testers from diverse genetic backgrounds and phenotyped for agronomic traits.

29p viarchimedes 26-01-2022 9 0   Download

Isatin, 1H -indoline-2,3-dione, an endogenous compound, is also a synthetically versatile molecule that possesses a diversity of biological activities including anticonvulsant, antibacterial, antifungal, antiviral, anticancer, and cytotoxic properties. Based on the promising cytotoxic activity studies on N -substituted isatin derivatives, a series of 18 derivatives of 2-(2,3-dioxo-2,3-dihydro-1H -indol-1-yl)-N -phenylacetamide were designed, synthesized, and characterized according to their analytical and spectral data.

9p langthannam 29-12-2021 10 0   Download

A simple and efficient method for the synthesis of 6-aryl-3-oxo-2,3-dihydropyridazine-4-carbohydrazide derivatives was developed. The synthesis was achieved via one-pot multicomponent reaction of arylglyoxals, dialkylmalonates, and hydrazine hydrate in pyridine at room temperature. This procedure features high regioselectivity, generally good to excellent yields, the use of easily available starting materials, and operational simplicity. This chemistry provides an efficient and promising synthetic strategy for diversity-oriented construction of the 6-arylpyridazinone skeleton.

10p langthannam 29-12-2021 12 0   Download

This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural aspects of TPase inhibitors is also included to facilitate understanding of diverse approaches to monitor the design of new inhibitors. TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.

28p langthannam 29-12-2021 9 0   Download

The isocoumarins are naturally occurring lactones that constitute an important class of natural products exhibiting an array of biological activities. A wide variety of these lactones have been isolated from natural sources and, due to their remarkable bioactivities and structural diversity, great attention has been focused on their synthesis. This review article focuses on their structural diversity, biological applications, and commonly used synthetic modes.

26p langthannam 29-12-2021 11 0   Download

The tetrahydropyridine (THP) ring system has received considerable focus due to its excellent ability to act as a pharmacophore. It is recognized as a major constituent in natural alkaloids. THP derivatives have been reported for a diverse range of biological activities. Recent synthetic works contain syntheses of monosubstituted, disubstituted, trisubstituted, highly functionalized, and condensed structures. In this review, we summarize the recent literature dealing with the bioactive nature of this important heterocycle.

26p tudichquannguyet 29-11-2021 6 0   Download

In diverse plant taxa, whole-genome duplication (WGD) events are major sources of phenotypic novelty. Studies of gene expression in synthetic polyploids have shown immediate expression and functional partitioning of duplicated genes among different tissues. Many studies of the tissue-specific homeolog expression partitioning have focused on allopolyploids that have very different parental genomes, while few studies have focused on autopolyploids or allopolyploids that have similar parental genomes.

10p vitzuyu2711 29-09-2021 5 1   Download

Synthetic hexaploid wheat (SHW) is a reconstitution of hexaploid wheat from its progenitors (Triticum turgidum ssp. durum L.; AABB x Aegilops tauschii Coss.; DD) and has novel sources of genetic diversity for broadening the genetic base of elite bread wheat (BW) germplasm (T. aestivum L). Understanding the diversity and population structure of SHWs will facilitate their use in wheat breeding programs.

12p vitzuyu2711 29-09-2021 14 1   Download

Sequencing of microbiomes has accelerated the characterization of the diversity of CRISPR-Cas immune systems. However, the utilization of next generation short read sequences for the characterization of CRISPRCas dynamics remains limited due to the repetitive nature of CRISPR arrays.

12p visilicon2711 20-08-2021 9 1   Download

The aim of the study to provide basic potential of protease from bacillus species for diverse application biomedical as well as industrial use has been reported. Total 46 research article have been selected for the study and read out and make out a list of various industrial applications are screened under alkaline protease & industry, protein hydrolysis, food and feed industry, cowhide industry, cleasner, Photographic industry, element industry, silk degumming and clinical trials.

15p chauchaungayxua12 29-07-2021 15 1   Download

The human population on the planet is estimated to reach 9 billion by 2050; this requires significant increase of food production to meet the demands. Intensified farming systems have been identified as a viable means to increase grain production. Crop production inputs include carbon investment in the form of energy, for the manufacture and use of farm machinery, synthetic fertilizers, crop protection chemicals such as herbicides, insecticides and fungicides, groundwater irrigation and the direct use of fuel in farm operations.

26p caygaocaolon11 21-04-2021 24 2   Download

Modules of interacting components arranged in specific network topologies have evolved to perform a diverse array of cellular functions. For a network with a constant topological structure, its function within a cell may still be tuned by changing the number of instances of a particular component (e.g., gene copy number) or by modulating the intrinsic biochemical properties of a component (e.g., binding strength or catalytic efficiency).

12p vijisoo2711 27-10-2020 9 1   Download

The presence of heterocyclic moiety in diverse compounds, strongly indicative of the desired effect on physiological activity, and it reflects on efforts to find useful synthetic drugs.

12p tocectocec 25-05-2020 13 0   Download

Cancer is the most deadly disease in the world and cancer deaths are increasing rapidly in developed and developing countries. There are many types of cancer affecting people of all ages with no discrimination of age and sex. Treatment options are synthetic drugs and naturally derived drugs. The synthetic drugs have many side effects and are not preferred and there is a dire need to have a natural anticancer drug with novel mechanism of action.

15p caygaocaolon4 04-04-2020 12 0   Download

Bacteria grow very rapidly under warmth and moisture. Many plant extracts from roots, stem, leaves, flowers, fruits and seeds of diverse species of plants exhibit anti-bacterial properties. These can be used for treating the textiles and the relatively lower incidence of the adverse reaction of these treatments coupled with reduced cost can be exploited as an effective eco-friendly alternative to the synthetic antimicrobial agents for textile applications.

6p caygaocaolon4 04-04-2020 16 1   Download

Bananas (Musa spp.) are mostly diploid or triploid with various combinations of genomes inherited from their ancestors. Inter simple sequence repeat (ISSR) markers were used for evaluation of genetic diversity of some synthetic Banana Hybrids. A total of 10 primers were evaluated for banana hybrids based on ISSR polymorphism. Diversity analysis carried out by using ISSR markers in some Banana hybrids revealed the confirmation of the hybridization along with the phylogenetic relationship of the hybrids with their parents. Out of the 10 primers studied, six primers exhibited scorable markers.

12p caygaocaolon4 01-04-2020 15 1   Download