Diversity and complexity

The rationale for this study is that the social enterprise sector provides an important locale in which to situate research that aims to identify the impact of ICTs on development. Recognising the complex dynamics and range of actors involved in this diverse and emerging area of development practice, this study chooses to focus on the social enterprise sector. It is specifically concerned with mapping the external influences, use and impact of ICT on social enterprises in Cambodia.

228p runthenight04 02-02-2023 22 3   Download

This thesis has proposed two systems: the RIM-OFDM system with diversity reception exploits simultaneously the frequency and spatial diversity to achieve better SEP performance than the conventional IM-OFDM with diversity reception; The RIM-OFDM system with CI attains higher reliability and flexibility than the conventional IM-OFDM-CI system. The low-complexity detectors were also proposed to reduce the complexity while still achieve nearly same performance of the ML detector.

26p gaocaolon6 30-07-2020 34 3   Download

Cycads occur in lowland forests and are threatened by their degradation, fragmentation and over-exploitation. Our results indicate that cycad population sizes were very small (less 100 individuals) with high propagules. These increased mating between closely related individuals growing in clumps. The allozyme data show although all studied cycads maintained high levels of genetic diversity, an average of 0.556 (0.491 in C. hoabinhensis to 0.598 in C. chevalieri ), the degree of inbreeding was high.

10p 12120609 01-06-2020 17 3   Download

In this study, the selective oximation of structurally diverse aromatic aldehydes (versus ketones) to the corresponding aldoxime derivatives was investigated using the combination system of NH2OH·HCl and bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides, MII(tu)2Cl2, in a mixture of CH3CN-H2O (1:1).

10p tocectocec 25-05-2020 13 2   Download

a2 -Macroglobulin (a2M) is an abundant glycoprotein with the intrinsic capacity for capturing diverse proteins for rapid delivery into cells. After internalization by the receptor-mediated endocytosis,a2M-protein complexes were rapidly degraded in the endolysosome system. Although this is an importantpathway for clearanceofbotha2Mandbiological targets, little is known about the nature ofa2M degradation in the endolysosome system.

10p tumor12 20-04-2013 33 3   Download

Multi-protein complexes are emerging as important entities of biological activity inside cells that serve to create func-tional diversity by contextual combination of gene products and, at the same time, organize the large number of different proteins into functional units. Many a time, when studying protein complexes rather than individual proteins, the bio-logical insight gained has been fundamental, particularly in cases in which proteins with no previous functional anno-tation couldbe placed intoa functional context derived from their
molecular environment. ...

9p tumor12 20-04-2013 38 2   Download

Originally the term ‘protein module’ was coined to distinguish mobile domains that frequently occur as building blocks of diverse multidomain proteins from ‘static’ domains that usually exist only as stand-alone units of single-domain proteins. Despite the widespread use of the term ‘mobile domain’, the distinction between static and mobile domains is rather vague as it is not easy to quantify the mobility of domains.

15p fptmusic 12-04-2013 44 1   Download

The protein tyrosine phosphatase PTP-Basophil (PTP-Bas) and itsmouse homologue, PTP-Basophil-like (PTP-BL), are high molecular mass protein phosphatases consisting of a number of diverse protein–protein interaction modules. Several splicing variants of these phosphatases are known to exist thus demonstrating the complexity of these molecules. PTP-Bas/BL serves as a central scaffolding protein facilita-ting the assembly of a multiplicity of different proteins mainly via five different PDZ domains. ...

10p fptmusic 12-04-2013 36 2   Download

Functional diversity of potassium channels in both prokaryotic and euk-aryotic cells suggests multiple levels of regulation. Posttranslational regula-tion includes differential subunit assembly of homologous pore-forming subunits. In addition, a variety of modulatory subunits may interact with the pore complex either statically or dynamically. Kv2.1 is a delayed recti-fier potassium channel isolated by expression cloning.

13p fptmusic 11-04-2013 36 2   Download

Cone snails comprise
500 species of venomous molluscs, which have evolved the ability to generate multiple toxins with varied and often exquisite selectivity. One class, the a-conotoxins, is proving to be a powerful tool for the differentiation of nicotinic acetylcholine receptors (nAChRs). These comprise a large family of complex subtypes, whose significance in physiological functions and pathological conditions is increasingly becoming apparent.

15p dell39 03-04-2013 47 4   Download

Recent studies suggest that diverse types of intronic and small non-coding RNAs play pivotal regulatory roles, often as a part of ribonucleoprotein (RNP) complexes, in a variety of cellular proces-ses such as transcription and translation. Thus, isolation and char-acterization of novel RNP complexes, such as micro RNPs, small nuclear RNPs, small nucleolar RNPs, and heteronuclear RNPs, are crucial to understand the biological systems.

20p galaxyss3 19-03-2013 44 2   Download

The pseudouridine synthase and archaeosine transglycosylase (PUA) domain is a compact and highly conserved RNA-binding motif that is widespread among diverse types of proteins from the three kingdoms of life. Its three-dimensional architecture is well established, and the structures of several PUA–RNA complexes reveal a common RNA recognition sur-face, but also some versatility in the way in which the motif binds to RNA.

13p media19 04-03-2013 33 2   Download

The mannose 6-phosphate⁄insulin-like growth factor II receptor has diverse ligand-binding properties contributing to its roles in lysosome biogenesis and growth suppression. Optimal receptor binding and internalization of mannose 6-phosphate (Man-6-P)-bearing ligands requires a dimeric struc-ture leading to bivalent high-affinity binding, presumably mediated by cooperation between sites on both subunits.

15p viettel02 22-02-2013 33 4   Download

Virtually every process in a cell is carried out by macromolecular com-plexes whose actions need to be perfectly orchestrated. The synchronization and regulation of these biological functions is indeed critical and is usually carried out by complex networks of transient protein interactions. Here, we review some of the many strategies that proteins in regulatory networks use to achieve the dynamic plasticity necessary to rapidly respond to diverse cellular needs.

16p viettel02 20-02-2013 30 4   Download

The LC8 family members of dynein light chains (DYNLL1 and DYNLL2 in vertebrates) are highly conserved ubiquitous eukaryotic homodimer pro-teins that interact, besides dynein and myosin 5a motor proteins, with a large (and still incomplete) number of proteins involved in diverse biologi-cal functions.

17p cosis54 04-01-2013 27 4   Download