DNA interaction

This book is divided into five parts: Part I introduces molecular genetic methods to study bacterial nucleoids; Part II highlights the study of bacterial nucleoid with whole genome analysis method; Part III discusses molecular biology methods to study nucleoid structuring factors; Part IV looks at imaging bacterial nucleoid; and Part V explores biophysics of the bacterial nucleoid.

369p vimeyers 29-05-2024 1 1   Download

In this study, a facile synthesis and grafting method is reported for tetradentate Cu(II) Schiff base complex onto the surface of graphene oxide (GO). The Schiff base Cu-complex was synthesized through the condensation reaction between 2,3-diamino pyridine and 2-hydroxy-1-naphthaldehyde, followed by the addition of Cu(II) ion to afford N2O2-Cu(II) complex.

17p dianmotminh02 03-05-2024 3 1   Download

Ebook "Biophysics of DNA-protein interactions: From single molecules to biological systems" would focus on the specific topic of the biophysics of DNA-protein interactions, and would include the use of new approaches, including both bulk methods as well as single molecule methods. This would make the book attractive to anyone working in the general area of DNA-protein interactions, which is of course a much wider market than just single molecule biophysicists or even biophysicists.

354p ladongphongthanh1008 22-04-2024 7 2   Download

Ebook "CtBP family proteins" are unique in several aspects. They were the first among proteins containing a metabolic enzyme fold to be implicated in transcriptional regulation. The vertebrate CtBPs exhibit distinct nuclear and cytosolic activities. The crystal struaures of CtBPl and molecular modeling studies have illuminated the molecular basis of its dual activity and the interaction with target peptides.

131p ladongphongthanh1008 22-04-2024 5 2   Download

The discovery of synthetic lethal interactions between poly (ADP-ribose) polymerase (PARP) inhibitors and BRCA genes, which are involved in homologous recombination, led to the approval of PARP inhibition as a monotherapy for patients with BRCA1/2-mutated breast or ovarian cancer.

12p vibransone 28-03-2024 3 2   Download

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex heritability and higher prevalence in males. The neonatal epigenome has the potential to reflect past interactions between genetic and environmental factors during early development and influence future health outcomes.

25p vibransone 28-03-2024 5 1   Download

Twin studies are powerful models to elucidate epigenetic modifications resulting from gene–environment interactions. Yet, commonly a limited number of clinical twin samples are available, leading to an underpowered situation afflicted with false positives and hampered by low sensitivity.

15p vioraclene 31-03-2024 6 2   Download

Krüppel-type zinc finger genes (ZNF) constitute a large yet relatively poorly characterized gene family. ZNF genes encode proteins that recognize specific DNA motifs in gene promotors. They act as transcriptional co-activators or -repressors via interaction with chromatin remodeling proteins and other transcription factors.

10p vioraclene 31-03-2024 1 1   Download

Colorectal adenocarcinomas are characterized by abnormal mitochondrial DNA (mtDNA) copy number and genomic instability, but a molecular interaction between mitochondrial and nuclear genome remains unknown. Here we report the discovery of increased copies of nuclear mtDNA (NUMT) in colorectal adenocarcinomas, which supports link between mtDNA and genomic instability in the nucleus.

15p vioraclene 31-03-2024 4 1   Download

Basal cell carcinoma (BCC) of the skin is the most common form of human cancer, with more than 90% of tumours presenting with clear genetic activation of the Hedgehog pathway. However, polygenic risk factors affecting mechanisms such as DNA repair and cell cycle checkpoints or which modulate the tumour microenvironment or host immune system play significant roles in determining whether genetic mutations culminate in BCC development.

12p vibransone 28-03-2024 3 2   Download

Ebook "Nano-bio probe design and its application for biochemical analysis" eview the concept of nano-bio probe design for biochemical analysis on the basis of their recent published works. A unique biochemical analysis technology based on fluorescence polarization enhanced by nanoparticles is described here with successful applications in environmental monitoring, rapid and sensitive sensing protease activity and high-throughput screening of inhibitors.

83p coduathanh1122 27-03-2024 1 1   Download

Ebook "Modern molecular biology: Approaches for Unbiased discovery in cancer research" is to provide an overview of modern molecular biological approaches to unbiased discovery in cancer research. Advances in molecular biology allowing unbiased analysis of changes in cancer initiation and progression will be overviewed. These include the strategies employed in modern genomics, gene expression analysis, and proteomics.

196p cotieubac1004 15-03-2024 1 0   Download

Ebook "Cell and tissue engineering" introduces the principles and new approaches in cell and tissue engineering. It includes both the fundamentals and the current trends in cell and tissue engineering, in a way useful both to a novice and an expert in the field. The book is composed of 13 chapters all of which are written by the leading experts. It is organized to gradually assemble an insight in cell and tissue function starting form a molecular nano-level, extending to a cellular micro-level and finishing at the tissue macro-level.

287p manmanthanhla0201 26-02-2024 3 1   Download

Ebook "Analytics of Protein–DNA interactions (Advances in biochemical engineering/biotechnology, Volume 104)" focuses on the fascinating possibilities that emerged during the last years to study protein–DNA interactions in vitro. As an essential part of transcriptional activity during development and in tumorgenesis a separate chapter describing the analysis of DNA modification especially methylation of cytosines at their carbon-5 position was included.

212p manmanthanhla0201 27-02-2024 4 2   Download

Ebook "Biocompatible graphene for bioanalytical applications" highlights the latest advances in the use of graphene and bio-compatible-material-decorated graphene to detect various targets (e.g. DNA, RNA, amino acids, peptides, proteins, enzymes, antigens, glucose, DA, AA, UA, ATP, NADH, gas, ions, etc.). It focuses on the specific interaction of these substances with graphene (or modified graphene) and the efficient transduction of the target recognition event into detectable signals via various techniques.

122p nhanphanguyet 28-01-2024 4 2   Download

Ebook "Eriophyoid mites: Progress and prognoses" dealing with their DNA, species interactions, adventiveness, host specificity, potential as boi-contol agents of weeds, chemical control, behaviour, their role in fungal pathogen epidemiology, influence in forests and on ornamentals, collecting and mounting techniques and their interaction with crops are presented here. This is an extensive and valuable contribution to eriophyoid science and a must for present and future researchers in this field.

306p tachieuhoa 28-01-2024 3 2   Download

Part 2 book "Animal microbiology" includes content: Viral structure and classification, viral replication, heredity and evolution of virus, virus–cell interactions, pathogenesis of viruses, detection of virus infection; double stranded DNA viruses; herpesvirales; single stranded DNA viruses; retroviruses; double stranded RNA viruses; mononegavirales, minus strand RNA viruses of segmentation, nidovirales; picornavirales, other viruses of positive sense RNA, prion; bacteriophage.

190p muasambanhan04 14-01-2024 3 2   Download

Ebook "Plant chromatin dynamics: Methods and protocols" provides a comprehensive collection of protocols that can be used to study plant chromatin structure and composition. Chapters divided into three sections detail the profiling of chromatin features in relation to epigenetic regulation, investigate the interaction between chromatin modifications and gene regulation, and explore the 3D spatial organization of the chromatin inside the nucleus.

650p lucchinguyen 28-12-2023 6 3   Download

Disco-interaction protein 2 homologue B (DIP2B) plays an important role in DNA methylation. There have been many reports on DIP2B in various diseases, but neither the diagnostic value nor the prognostic value of DIP2B across cancer types has been deeply explored.

20p vischultz 20-10-2023 3 2   Download

Long noncoding RNAs (lncRNAs) are considered key players in the formation and development of tumors. Herein, Gene Expression Profiling Interactive Analysis (GEPIA) was employed as a bioinformatics technology.

15p visharma 20-10-2023 6 2   Download