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Dorsolateral prefrontal cortex
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Neuropsychiatric disorders afflict a large portion of the global population and constitute a significant source of disability worldwide. Although Genome-wide Association Studies (GWAS) have identified many disorderassociated variants, the underlying regulatory mechanisms linking them to disorders remain elusive, especially those involving distant genomic elements.
15p
viellison
28-03-2024
5
2
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Circular RNAs (circRNAs) are implicated in various biological processes. As a layer of the gene regulatory network, circRNA expression is also an intermediate phenotype bridging genetic variation and phenotypic changes. Thus, analyzing circRNA expression variation will shed light on molecular fundamentals of complex traits and diseases.
16p
vigalileogalilei
27-02-2022
10
1
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Despite the considerable success of comprehensive tobacco control efforts, tobacco use remains one of the greatest preventable causes of death and disease today. Over half of all smokers in the US make quit attempts every year, but over 90% relapse within 12 months, choosing the immediate reinforcement of smoking over the long-term benefits of quitting.
14p
vigeorgia2711
30-11-2020
12
3
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Lateral (top) and medial (bottom) views of the cerebral hemispheres. The numbers refer to the Brodmann cytoarchitectonic designations. Area 17 .corresponds to the primary visual cortex, 41–42 to the primary auditory cortex, 1– 3 to the primary somatosensory cortex, and 4 to the primary motor cortex. The rest of the cerebral cortex contains association areas.
29p
socolanong
25-04-2012
75
3
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