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Double screening
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Double reading (DR) in screening mammography increases cancer detection and lowers recall rates, but has sustainability challenges due to workforce shortages. Artificial intelligence (AI) as an independent reader (IR) in DR may provide a cost-effective solution with the potential to improve screening performance.
13p
visharma
20-10-2023
4
2
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Non-invasive prenatal testing (NIPT) is being applied more widely in Vietnam. However, the effects of NIPT on prenatal diagnosis have not been studied much in our country. This study aims to analyze the impact of NIPT on the changes in the number of routine screening tests for chromosomal abnormalities 21, 18, and 13 and the impact of NIPT on invasive prenatal diagnostic procedures and propose strategies to screen for fetal aneuploidy.
7p
vimclaren
20-10-2022
5
2
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Dementia is a neuro-degenerative condition resulting in cognitive and physical decline over time. In the early stages of the condition, physical decline may be slow, but in the later stages, it may become more pronounced.
10p
vinobelprisen
26-03-2022
12
5
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Systems for CRISPR-based combinatorial perturbation of two or more genes are emerging as powerful tools for uncovering genetic interactions. However, systematic identification of these relationships is complicated by sample, reagent, and biological variability.
10p
vigalileogalilei
27-02-2022
7
1
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X-chromosomal genes contribute to sex differences, in particular during early development, when both X chromosomes are active in females. Double X-dosage shifts female pluripotent cells towards the naive stem cell state by increasing pluripotency factor expression, inhibiting the differentiation-promoting MAP kinase (MAPK) signaling pathway, and delaying differentiation.
41p
viarchimedes
26-01-2022
7
0
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Clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins (CRISPR/Cas) is an acquired immune system found in bacteria and archaea that can specifically silence or degrade a foreign single or double strand nucleic acid to protect it from infection. In recent years, the CRISPR/Cas9 system has rapidly been evolved into a genome editing technology, in which the Cas9 endonuclease can be targeted to specific DNA sequences by guide RNAs (gRNAs) that are easily programmable.
16p
tudichquannguyet
29-11-2021
21
1
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Screening for lung cancer has used chest radiography (CR), low dose computed tomography (LDCT) and sputum cytology (SC). Estimates of the lead time (LT), i.e., the time interval from detection of lung cancer by screening to the development of symptoms, have been derived from longitudinal studies of populations at risk, tumor doubling time (DT), the ratio between its prevalence at the first round of screening and its annual incidence during follow-up, and by probability modeling derived from the results of screening trials.
8p
vimichigan2711
26-03-2021
9
1
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In the present investigation, an attempt was made to assess the compatibility of six agrochemicals such as Fungicides (Metalaxyl and Tricyclazole), Insecticides (Profenophos and Chloranthraniliprole) and Herbicides (Glyphosate and Atrazine) against five potassium releasing bacterial and two fungal isolates from Rajendranagar, Hyderabad. Compatibility tests indicated that glyphosate has much severe effect on microbial biomass at low, recommended and double doses.
7p
cothumenhmong9
18-01-2021
14
2
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In the present study, 15 genotypes of Brassica juncea including white rust resistant and double low quality were characterized and allelic differentiation was determined using 453 SSRs and 139 (30.7%) showed polymorphism with 308 alleles. Polymorphic information content ranged from 0.101 to 0.668, with the average value of 0.474, revealing that much variation was present among these genotypes.
11p
caygaocaolon8
07-11-2020
12
2
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Meganucleases are important tools for genome engineering, providing an efficient way to generate DNA double-strand breaks at specific loci of interest. Numerous experimental efforts, ranging from in vivo selection to in silico modeling, have been made to re-engineer meganucleases to target relevant DNA sequences.
11p
vikentucky2711
26-11-2020
10
0
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Extended spectrum beta lactamase producers are posing a major obstacle in the therapeutic outcome of patients. They cause enzymatic hydrolysis of the beta lactum ring, resulting in resistance to penicillins and cephalosporins. The rise in ESBL producers results in prolonged treatment which leads to increased hospital stay and financial burden on the patient. It is necessary for all the hospitals to monitor ESBL producers to formulate preventive and therapeutic measures accordingly. The study was conducted in a tertiary care hospital during the period from December 2015 to November 2016.
7p
angicungduoc8
07-11-2020
15
1
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Two field experiments were conducted at Hyderabad and Aurangabad in India under water stress at flowering and well watered condition during the rabi season (2018). The objective of the study was to assess the drought tolerance traits in maize DHL’s x Tester (Top cross hybrids).
10p
caygaocaolon6
30-07-2020
7
1
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Metallo-β-lactamases (MβLs) production in gram negative bacilli is an emerging health problem worldwide. We aimed to determine the occurrence of MβLs among gram negative bacilli (GNB) by phenotypic and genotypic methods in Mansoura University hospital, Egypt. We conducted a prospective study on 107 GNB isolates recovered from different clinical specimens collected from different patients. Species identification and antibiotic susceptibility profile was determined by MicroScan Wa1kAway system.
10p
nguaconbaynhay6
24-06-2020
7
0
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Immunochemical fecal occult blood tests (iFOBTs) are increasingly used for colorectal cancer (CRC) screening. In our preceding observational study, sensitivity for detecting advanced colorectal neoplasms by iFOBT was 70.8% among users of low-dose acetylsalicylic acid compared with 35.9% among non-users (p = 0.001), whereas there were only very small differences in specificity.
9p
vimanila2711
25-06-2020
17
0
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To date, no single colorectal cancer (CRC) screening strategy has been determined to be applicable worldwide. In China, a CRC screening protocol that combines double fecal immunochemical tests (FITs) and a high-risk factor questionnaire (HRFQ) as the first stage of screening and colonoscopy as the second stage of screening (scenario A) was adapted by the Chinese Ministry of Health in 2006.
8p
viputrajaya2711
22-06-2020
7
0
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The aim of this study was to analyze the extended spectrum of β lactamase (ESBL), metallo β lactamase (MBL) and AmpC production in Pseudomonas aeruginosa in various clinical samples. A Total of 100 clinical isolates of P. aeruginosa were collected from different clinical specimen and confirmed by standard tests. Antibiotic susceptibility was determined by the Kirby-Bauer disc diffusion method. ESBL screening was done using 3rd generation cephalosporins and confirmatory combined double disc test, imipenem-EDTA double disc synergy test for MBL enzyme and AmpC test using Cefoxitin disc.
9p
trinhthamhodang1213
30-05-2020
11
1
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In the current study prevalence and characterization of extended spectrum betalactamase(ESBL) production of Escherichia coli was detected from broilers of West Bengal, India. A total of 248 cloacal swabs samples were examined for E.coli by standard bacteriological techniques. E.coli isolates were serotyped and also screened for extended spectrum beta-lactamase by double disc diffusion assay and by PCR detection of blaCTX-M, blaSHV, and blaTEM genes.
9p
caygaocaolon4
04-04-2020
15
2
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Rural Indian women are extensively involved in agricultural activities. Grain cleaning and grading for women in rural area is a big problem because they use traditional sieve for cleaning and grading manually in sitting posture. This posture increases the fatigue and drudgery of farm women while cleaning and grading which results in aches and pains in the back and cervical region. This is time consuming method and output realized is less.
10p
caygaocaolon4
04-04-2020
15
2
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Iron deficiency prevalence rates frequently exceed 50 % in young children in low-income countries. The World Health Organization (WHO) recommended universal supplementation of young children where anaemia rates are >40 %. However, large randomized trials have revealed that provision of iron to young children caused serious adverse effects because iron powerfully promotes microbial growth.
9p
videshiki2711
21-02-2020
39
1
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The CRISPR/Cas9 system has been used predominantly for precise editing of the plant genomes. In the present study, we have made an application of CRISPR/Cas9 system for targeted mutagenesis in rice(Oryza sativa L.) targeting the Phytochrome and Flowering Time 1 (PFT1) gene known to be involved in disease susceptibility in Arabidopsis for rootinfecting hemibiotrophic fungal pathogen Fusarium oxysporum. Hence, to confirm the role of OsPFT1 gene in rice sheath blight disease, CRISPR-Cas9 gene editing tool is being employed for generating OsPFT1 gene knock out in rice.
9p
chauchaungayxua3
07-02-2020
8
0
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