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Downstream analysis
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Transcriptional Co-Activator with PDZ-Binding Motif (TAZ, also known as WWTR1) is a downstream effector of the Hippo pathway, involved in the regulation of organ regeneration and cell differentiation in processes such as development and regeneration.
12p
vikoch
27-06-2024
1
1
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In the study "Distribution, fate and ecological toxicity of some heavy metals in sediment: A case study from Day river downstream, Vietnam" the 50 surface sediment samples were collected along Day River downstream in July 2018 and January 2019 (25 sampling sites) to clarify the status, movement and potential risk of some heavy metals (Cr, Pb, Cu, Cd and Hg). The receptor model of Principal Component Analysis (PCA) was applied to track the source types of these metals.
11p
tukhauquantuong1011
22-04-2024
6
3
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Next-generation sequencing technologies have enabled a dramatic expansion of clinical genetic testing both for inherited conditions and diseases such as cancer. Accurate variant calling in NGS data is a critical step upon which virtually all downstream analysis and interpretation processes rely.
13p
vibransone
28-03-2024
4
2
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The study aimed to conduct a situational analysis of the shallot supply chain in Majalengka Regency, which experienced problems with production and price instability. Without a clear situational analysis, intervention becomes more difficult.
16p
longtimenosee07
29-03-2024
4
2
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The paper aim to investigate the current state of researches, current development, gaps and provide guidance for future research of innovation system and agricultural downstream supply chain research field. A systematic literature review (SLR) method was implemented to achieve the research objective. After applying some relevant keywords filter and including some relevant papers published in the field, 110 papers addressing the innovation system in agricultural downstream supply chain are identified for review analysis.
13p
longtimenosee06
27-03-2024
6
2
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This study aims to analyze the effects of supply chain influence on initial Public Offering (IPO) and its implications on long term underperformance which is peroxided with the IHSG of IPO shares on the Indonesia stock exchange. IPO in this study is in 2016 with an analysis of 5 years period (2016-2020). The method used is the Purposive Sampling Method.
16p
longtimenosee06
27-03-2024
5
1
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N-myc downstream-regulated gene-1 (NDRG1) is well-described as a potent metastasis suppressor, but its role in human breast cancer remains controversial and unclear. Therefore, the present study utilized a systematic review and meta-analysis approach to synthesize the association between NDRG1 protein expression and the aggressive characteristics of breast cancer.
11p
visharma
20-10-2023
4
2
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Quantify the downstream impact on patient wait times and overall length of stay due to small increases in encounter times caused by the implementation of a new electronic health record (EHR) system.
6p
visteverogers
24-06-2023
6
2
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The lymphatic and the blood vasculature are closely related systems that collaborate to ensure the organism’s physiological function. Despite their common developmental origin, they present distinct functional fates in adulthood that rely on robust lineage-specific regulatory programs.
10p
vihagrid
30-01-2023
4
3
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Transcriptome analysis to identify the downstream genes of androgen receptor in dermal papilla cells
Testosterone signaling mediates various diseases, such as androgenetic alopecia and prostate cancer. Testosterone signaling is mediated by the androgen receptor (AR). In this study, we fortuitously found that primary and immortalized dermal papilla cells suppressed AR expression, although dermal papilla cells express AR in vivo.
10p
vihagrid
30-01-2023
7
3
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Fourier-transform infrared spectroscopy (FTIR)is a well-established spectroscopic method in the analysis of small molecules and protein secondary structure. However, FTIR is not commonly applied for inline monitoring of protein chromatography.
8p
viginny
23-12-2022
9
2
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Plants are advantageous as biopharmaceutical manufacturing platforms because they allow the economical and scalable upstream production of proteins, including those requiring post-translational modifications, but do not support the replication of human viruses. However, downstream processing can be more labor-intensive compared to fermenter-based systems because the product is often mixed with abundant host cell proteins.
13p
viginny
23-12-2022
9
3
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Dimensionality reduction is an indispensable analytic component for many areas of single-cell RNA sequencing (scRNA-seq) data analysis. Proper dimensionality reduction can allow for effective noise removal and facilitate many downstream analyses that include cell clustering and lineage reconstruction.
21p
vielonmusk
30-01-2022
9
1
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Various efforts have been made to elucidate the cooperating proteins involved in maintaining chromatin interactions; however, many are still unknown. Here, we present 3CPET, a tool based on a non-parametric Bayesian approach, to infer the set of the most probable protein complexes involved in maintaining chromatin interactions and the regions that they may control, making it a valuable downstream analysis tool in chromatin conformation studies.
16p
viaristotle
29-01-2022
10
0
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Single-cell RNA sequencing (scRNA-seq) has broad applications across biomedical research. One of the key challenges is to ensure that only single, live cells are included in downstream analysis, as the inclusion of compromised cells inevitably affects data interpretation.
15p
viaristotle
29-01-2022
16
0
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Single-cell RNA-sequencing (scRNA-seq) technologies and associated analysis methods have rapidly developed in recent years. This includes preprocessing methods, which assign sequencing reads to genes to create count matrices for downstream analysis.
32p
viarchimedes
26-01-2022
16
0
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Recent advancements in next-generation sequencing have rapidly improved our ability to study genomic material at an unprecedented scale. Despite substantial improvements in sequencing technologies, errors present in the data still risk confounding downstream analysis and limiting the applicability of sequencing technologies in clinical tools.
13p
viarchimedes
26-01-2022
7
0
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Dropouts distort gene expression and misclassify cell types in single-cell transcriptome. Although imputation may improve gene expression and downstream analysis to some degree, it also inevitably introduces false signals. We develop DISC, a novel deep learning network with semi-supervised learning to infer gene structure and expression obscured by dropouts.
28p
viarchimedes
26-01-2022
8
0
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: RNA-Seq has become one of the most widely used applications based on next-generation sequencing technology. However, raw RNA-Seq data may have quality issues, which can significantly distort analytical results and lead to erroneous conclusions. Therefore, the raw data must be subjected to vigorous quality control (QC) procedures before downstream analysis. Currently, an accurate and complete QC of RNA-Seq data requires of a suite of different QC tools used consecutively, which is inefficient in terms of usability, running time, file usage, and interpretability of the results.
10p
vibeauty
23-10-2021
11
0
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Sequencing-based large screening of RNA-protein and RNA-RNA interactions has enabled the mechanistic study of post-transcriptional RNA processing and sorting, including exosome-mediated RNA secretion. The downstream analysis of RNA binding sites has encouraged the investigation of novel sequence motifs, which resulted in exceptional new challenges for identifying motifs from very short sequences (e.g., small non-coding RNAs or truncated messenger RNAs), where conventional methods tend to be ineffective.
17p
vibeauty
23-10-2021
10
0
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