Drug confinement

The recent pharmaceutical interest toward confinement effects on the physical state, solubility and release of drugs has paved the way to new material designs for drug delivery. Deeper understanding on how the pore size or the additional functionalities of the nanocarriers can influence the bioavailability of the cargo is nonetheless needed to explore further the potential of nanocarriers in this area.

8p vironald 15-12-2022 11 2   Download

Carbon-based nanoparticles and nanostructures, such as carbon nanotubes (CNTs), have drawn great attention in both academia and industry due to their wide potential applica‐ tions. Owing to their well-defined one-dimensional (1D) interior, CNTs serve as desirable materials for encapsulating molecules, such as water [1-4], ionic liquid [5], drug molecules [6], and biomolecules [7].

210p lyly_5 22-03-2013 44 4   Download

"In China, illicit drug use is an administrative offense and Chinese law dictates that drug users 'must be rehabilitated.' In reality, police raids on drug users often drive them underground, away from methadone clinics, needle exchange sites, and other proven HIV prevention services. And every year Chinese policy send tens of thousands of drug users to mandatory frug treatment centers, often for years, without trial or due process" -- p. [4] of cover.An Unbreakable CycleDrug Dependency Treatment, Mandatory Confinement, and HIV/AIDSin China’s Guangxi ProvinceI. Executive Summary ...........

48p konbetocroi 07-01-2013 47 2   Download

These findings along with a freely mobile prostate, normal serum acid phosphatase and normal skeletal radiographs suggested organ-confined disease and provided enough evidence to initiate radical treatment. In 1953, Colby retrospectively reviewed 100 prostatectomy specimens for presumed prostate cancer and of these 42 were performed solely on the basis of an abnormal digital rectal examination (DRE) (Colby 1953).

288p ti_du_hoang 10-08-2012 42 4   Download

The administration of general anaesthetics and neuromuscular blocking drugs is generally confined to trained specialists. Nevertheless, nonspecialists are involved in perioperative care and will benefit from an understanding of how these drugs act. Doctors from a variety of specialties use local anaesthetics and the pharmacology of these drugs is discussed in detail.

21p bigbaby87 03-09-2010 104 13   Download

This account is confined to therapy directed primarily at the skin. • Pharmacokinetics of the skin • Topical preparations:Vehicles for presenting drugs to the skin; Emollients, barrier preparations and dusting powders;Topical analgesics; Antipruritics; Adrenocortical steroids; Sunscreens • Cutaneous adverse drug reactions • Individual disorders: Psoriasis.Acne, Urticaria, Skin infections It is easy to do more harm than good with potent drugs, and this is particularly true in skin diseases.

18p bigbaby87 03-09-2010 68 13   Download