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Drug databases
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Precision oncology involves analysis of individual cancer samples to understand the genes and pathways involved in the development and progression of a cancer. To improve patient care, knowledge of diagnostic, prognostic, predisposing, and drug response markers is essential.
16p
vibransone
28-03-2024
4
2
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We present PhenCards (https://phencards.org), a database and web server intended as a one-stop shop for previously disconnected biomedical knowledge related to human clinical phenotypes. Users can query human phenotype terms or clinical notes. PhenCards obtains relevant disease/phenotype prevalence and co-occurrence, drug, procedural, pathway, literature, grant, and collaborator data.
9p
vibransone
28-03-2024
7
1
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Ebook "Applied bioinformatics: An introduction" introduces readers to the basic principles of bioinformatics and the practical application and utilization of computational tools, without assuming any prior background in programming or informatics. It provides a coherent overview of the complex field and focuses on the implementation of online tools, genome databases and software that can benefit scientists and students in the life sciences.
297p
tachieuhoa
28-01-2024
7
2
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Ebook "Pattern recognition in bioinformatics: 5th IAPR international conference, PRIB 2010 Nijmegen, The Netherlands, September 22-24, 2010 proceedings" has two main objectives: the creation and maintenance of biological databases and the analysis of life sciences data in order to unravel the mysteries of biological function. Computer science methods such as pattern recognition, machine learning, and data mining have a great deal to offer the field of bioinformatics.
458p
tachieuhoa
28-01-2024
4
2
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HER2-positive breast cancer (BC) invasiveness and drug-resistance issue is the critical treatment obstacle recently. We investigated the total and phosphorylated status EZH2 expression in database and BC tissue microarray. We demonstrated for the first time that EZH2 is distributed both in cytoplasm and nucleus of breast cancer cells in a phosphorylation site-specific manner.
11p
visharma
20-10-2023
6
2
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Multiple myeloma (MM) is a fatal malignant tumor in hematology. Mitophagy plays vital roles in the pathogenesis and drug sensitivity of MM. We acquired transcriptomic expression data and clinical index of MM patients from NCI public database, and 36 genes involved in mitophagy from the gene set enrichment analysis (GSEA) database.
18p
vioracle
29-09-2023
3
2
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To understand the current situation of China's health food, and to provide a reference for the development of Healthcare Industry. Methods: Create a database of China's health food information from China Food and Drug Administration website.
5p
viisac
23-09-2023
1
1
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All default electronic health record and drug reference database vendor drug-dose alerting recommendations (single dose, daily dose, dose frequency, and dose duration) were silently turned on in inpatient, outpatient, and emergency department areas for pediatric-only and nonpediatric-only populations.
6p
visteverogers
24-06-2023
8
2
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The Food & Drug Administration (FDA) is considering the permanent exemption of premarket notification requirements for several Class I and II medical device products, including several artificial Intelligence (AI)– driven devices. The exemption is based on the need to rapidly more quickly disseminate devices to the public, estimated cost-savings, a lack of documented adverse events reported to the FDA’s database.
3p
vighostrider
25-05-2023
2
2
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Non-steroid anti-inflammatory drugs (NSAIDs) have been proposed as part of a multimodal postoperative analgesia in patients operated for colorectal cancer. However, whether these drugs are prescribed and taken by the patients have not been evaluated. The aim of this study was to quantify the postoperative use of NSAIDs in these patients.
5p
viisaacnewton
26-04-2022
11
1
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Massive genome sequencing data have inspired new challenges in personalized treatments and facilitated oncological drug discovery. We present a comprehensive database, My Personal Mutanome (MPM), for accelerating the development of precision cancer medicine protocols.
18p
viarchimedes
26-01-2022
8
1
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The comparative efficacy of ancillary drugs on sevoflurane related emergence agitation (EA) in children undergoing ophthalmic surgery remains controversial. Methods: The databases were retrieved in an orderly manner from the dates of their establishment to October, 2018, including PubMed, The Cochrane Library and Web of Science.
11p
vidietmarhopp
29-12-2021
10
0
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This study aimed to identify potential circular ribonucleic acid (circRNA) signatures involved in the pathogenesis of early-stage lung adenocarcinoma (LAC). The circRNA sequencing dataset of early-stage LAC was downloaded from the Gene Expression Omnibus database.
11p
vimahuateng
26-11-2021
15
1
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In the second part, recent database of compounds provided worldwide and drug-like parameters which are helpful in supporting for the virtual screening process will be discussed. This information will provide a good platform to estimate the advance of applying these techniques in the new drug-lead identification and optimization.
26p
spiritedaway36
25-11-2021
6
1
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Immune checkpoint inhibitors-induced myocarditis presents unique clinical challenges. Here, we assessed post-marketing safety of cytotoxic T-lymphocyte-associated protein-4 (CTLA-4), programmed cell death-1 (PD-1), and programmed death-ligand 1 (PD-L1) inhibitors by mining the real-world data reported in two international pharmacovigilance databases.
9p
vianrose2711
27-04-2021
9
1
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In this study, we draw a big picture of personalized medicine research in cancer research of the –omics data era, including –omics databases, challenges of data fusion to solve two major problems in personalized medicine, i.e., personalized diagnosis and treatment. These problems are approached as patient stratification and drug response prediction based on the –omics data by computational methods.
8p
nguaconbaynhay11
16-04-2021
13
2
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Interstitial lung diseases (ILDs), a diverse group of diffuse lung diseases, mainly affect the lung parenchyma. The low-throughput ‘omics’ technologies (genomics, transcriptomics, proteomics) and relative drug information have begun to reshaped our understanding of ILDs, whereas, these data are scattered among massive references and are difficult to be fully exploited.
6p
vimichigan2711
26-03-2021
14
2
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Rheumatoid arthritis (RA) patients failing disease modifying antirheumatic drugs (DMARDs) may undergo anti-Tumor Necrosis Factor (anti-TNF) therapy. Using the Quebec health services administrative databases, we examined the rates of musculoskeletal (MSD)-related hospitalizations among RA patients receiving anti-TNF, DMARDs, and neither of those therapies (non-users).
10p
vioregon2711
22-02-2021
8
1
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Biomarkers and target-specific phenotypes are important to targeted drug design and individualized medicine, thus constituting an important aspect of modern pharmaceutical research and development. More and more, the discovery of relevant biomarkers is aided by in silico techniques based on applying data mining and computational chemistry on large molecular databases.
17p
viwyoming2711
16-12-2020
15
1
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Discovering novel interactions between HIV-1 and human proteins would greatly contribute to different areas of HIV research. Identification of such interactions leads to a greater insight into drug target prediction. Some recent studies have been conducted for computational prediction of new interactions based on the experimentally validated information stored in a HIV-1-human protein-protein interaction database.
22p
vikentucky2711
26-11-2020
13
1
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