Dynamic model selection

Heteronuclear NMR relaxation measurements and hydro-gen exchange data have been used to characterize protein dynamics in the presence or absence of stabilizing solutes from hyperthermophiles. Rubredoxin from Desulfovibrio gigaswas selected as a model protein and the effect of diglycerol phosphate on its dynamic behaviour was studied. The presence of 100 mMdiglycerol phosphate induces a fourfold increase in the half-life for thermal denaturation ofD.

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Whereas current building codes legally apply to seismic design of tall buildings, their prescriptive provisions do not adequately address many critical aspects. Performance-based engineering provides a desirable alternative.

19p tranduyphung 24-08-2011 194 17   Download